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Displaying 1 - 25 of 76

Engineering 3D Printed Scaffolds with Tunable Hydroxyapatite

June 15, 2022
Yoontae Kim, Eun Jin Lee, Anthony Kotula, Shozo Takagi, Laurence C. Chow, Styliani Alimperti
Bone grafting is a surgical procedure to bone repair due to trauma or diseases in the craniofacial and dental area. Current limitations of autogenous and allogeneic grafts are often associated with reduced host-graft integration due to geometrical confor

Mechanical Strength of Various Types of Calcium Phosphate Cements

October 12, 2021
Y Matsuya, S Matsuya, Joseph M. Antonucci, S. Takagi, Laurence Chow, A Akashi, A Akamine
It has been reported that organic or polymeric calcium phosphate cements can be made from reactive calcium phosphates with various organic acids or poly(alkenoic acids). Some of these cements are already commercially available for use as bioactive liners

Influence of Particle Size on DCPD Hydrolysis and Setting Properties of TTCP/DCPD Cement

February 19, 2017
Limin Sun, Laurence C. Chow, Shozo Takagi, Elena F. Burguera, Stanislav Frukhtbeyn
This study investigated the effects of particle size on the hydrolysis reaction of DCPD at pH 7 and 37 C and on the setting properties of a TTCP/DCPD cement. The kinetics of the hydrolysis reaction was controlled by a nucleation and growth mechanism

Gradient Nanofiber Scaffold Libraries for Screening Cell Response to Poly(e-caprolactone)-Calcium Phosphate Composites

March 1, 2013
Carl G. Simon Jr., Limin Sun, Laurence C. Chow, William Miles, Christopher K. Tison, Kaushik Chatterjee, Marian F. Young, Vinoy Thomas, Murugan Ramalingam
A 2-spinnerette approach has been developed for fabricating nanofiber scaffold gradients for use as 1) scaffold libraries for screening the effect of nanofiber properties on cell response and 2) templates for generating graded tissue interfaces. Although

A new approach to prepare well-dispersed CaF2 nanoparticles by spray drying technique

August 5, 2011
Limin Sun, Laurence C. Chow, John E. Bonevich, James W. Mitchell
Previously, a nano-sized calcium fluoride (CaF2) was prepared using a spray drying method by simultaneously feeding Ca(OH)2 and NH4F solutions to a two-liquid nozzle. The aim of the present study was to prepare better-dispersed nano CaF2 particles by co

In Vitro and in Vivo Characteristics of Fluorapatite-forming Calcium Phosphate Cements

August 1, 2010
Shozo Takagi, Stanislav A. Frukhtbeyn, Laurence C. Chow, Akiyoshi Sugawara, Kenji Fujikawa, Kidehiro Ogata, Makoto Hayashi, Bunnai Ogiso
This study reports for the first time in vitro and in vivo properties of fluorapatite (FA)-forming calcium phosphate cements (CPCs). The experimental cements contained from (0 to 3.3) mass % of F, corresponding to presence of FA at levels of approximately

Novel CaF2 Nanocomposite with High Strength and F Ion Release

May 3, 2010
Hockin D. Xu, Jennifer L. Moreau, Limin Sun, Laurence Chow
Secondary caries and restoration fracture remain the two most common problems. The objectives of this study were to develop stress-bearing, fluoride-releasing nanocomposites. Novel CaF2 nanoparticles (56-nm) were synthesized via spray-drying and

An Octacalcium Phosphate Forming Cement

April 16, 2010
Milenko Markovic, Laurence C. Chow
The osteoconductive and possibly osteoinductive characteristics of OCP increased the interest in preparation of bone graft materials that contain OCP in its composition. Calcium phosphate cements (CPCs) were prepared using a mixture of α tricalcium

Properties of Injectable Apatite-Forming Premixed Cements

April 10, 2010
Yasushi Shimada, Laurence Chow, Shozo Takagi, Junji Tagami
A previously reported, premixed calcium phosphate cements (CPC) forms hydroxyapatite (HA) as the only product, but had a setting time greater than 60 min. This study investigated properties of fast-hardening HA-forming premixed CPCs. All cements consisted

No Calcium Fluoride Found in Plaque Following a NaF Rinse

February 24, 2010
Gerald L. Vogel, Livia M. Tenuta, Gary E. Schumacher, Laurence C. Chow
Background: Plaque calcium fluoride or biological/bacterial calcium-fluoride deposits appear to be the source of cariostatic concentrations of fluoride in plaque fluid. Aims: (1) To quantify the amount of plaque calcium fluoride after a NaF rinse. (2) To

Injectable Calcium Phosphate Cements

October 16, 2008
Laurence C. Chow, Milenko Markovic, Shozo Takagi
Self-hardening calcium phosphate cements (CPC) have been the subject of considerable interest in biomaterials research, especially as a bone graft material. The first published CPCs consisted of tetracalcium phosphate (TTCP) and dicalcium phosphate

Properties of Calcium Phosphate Carbonate Cements

October 16, 2008
Milenko Markovic, Shozo Takagi, Laurence C. Chow
The physicochemical and mechanical properties of two calcium phosphate carbonate cements (CPCC-1 and CPCC-2) formed in solution reaction of (1) [alpha]-tricalcium phosphate ([alpha]-TCP),[alpha]-Ca 3(PO 4)d2^, with calcium carbonate, CaCO 3, and (2)

Reduced Hardening Time of Calcium Phosphate Cements

October 16, 2008
Milenko Markovic, S. Takagi, Laurence C. Chow
The first self-hardening calcium phosphate cement (CPC) consisting of tetracalcium phosphate (TTCP, Ca 4(PO 4) 2O) and dicalcium phosphate anhydrous (DCPA, CaHPO 4) or dicalcium phosphate dihydrate (DCPD, CaHPO 4 H x 2H 2O) was developed in 1987. The CPC

Ca Pre-Rinse Greatly Increases Plaque and Plaque Fluid F After a F Rinse

May 1, 2008
Gerald L. Vogel, Gary E. Schumacher, Laurence C. Chow, Shozo Takagi, Clifton M. Carey
This study examines if a Ca pre-rinse/F rinse increased plaque and plaque fluid F relative to the F rinse alone. Subjects (n = 13) accumulated plaque two days before rinsing with: (1) 12 mmol/L F (NaF), (2) 150 mmol/L Ca rinse, (3) the Ca rinse followed by