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Histopathological Reactions of Calcium Phosphate Cement for Alveolar Ridge Augmentation Containing Hydroxyapatite-Coated Implants in Dog Mandibles

Published

Author(s)

A Sugawara, K Fujikawa, S K. Kusama, Shozo Takagi, Laurence Chow

Abstract

Previous studies have shown that a calcium phosphate cement (CPC), consisting of tetracalcium phosphate and dicalcium phosphate anhydrous, was highly biocompatible and more osteoconductive than presently used hydroxyapatite (Hap)-based materials. The objective of the present study was to evaluate the osteoconductivities of CPC that was used for the reconstruction of the defective alveolar ridge in conjunction with implant placements. Mature (4-5 years old) beagle dogs were used in this study. At the beginning of the experiment, all mandibular premolar teeth were extracted. After taking an impression of the exposed alveolar bone, a plaster model of each alveolar bone was formed from the impression. A self-cured resin block (thickness of less than 5 mm), that will be used as the model for the implant and ridge augmentation procedure, was prepared from the plaster model. A CPC block was duplicated from the resin block after pouring CPC paste into the impression model of the resin block. One month later, mucoperiosteal flaps were reflected and two commercially available Hap-coated cylindrical implants were placed on each side of the mandible. The exposed implants were surrounded by the CPC block, and the space between the CPC block and the implants or the crestal alveolar bone surface were filled with CPC paste. Six months after surgery, osteointegrated implants, surrounded by a CPC block and paste, were completely covered by natural bone.
Citation
Society for Biomaterials

Keywords

alveolar bone, calcium phosphate, cement, histopathology, implant, osteointegration

Citation

Sugawara, A. , Fujikawa, K. , Kusama, S. , Takagi, S. and Chow, L. (2021), Histopathological Reactions of Calcium Phosphate Cement for Alveolar Ridge Augmentation Containing Hydroxyapatite-Coated Implants in Dog Mandibles, Society for Biomaterials (Accessed February 23, 2024)
Created October 12, 2021