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Displaying 76 - 100 of 1412

Engineering ClpS for Selective and Enhanced N-terminal Amino Acid Binding

March 1, 2019
Author(s)
Jennifer A. Tullman, Zvi Kelman, John P. Marino
… a high specificity albeit modest affinity for the amino acid Phe at the N-terminus but also recognizes the residues … directed evolution, yeast display, amino acid binding, peptide sequencing … ClpS for Selective and Enhanced N-terminal Amino Acid Binding …

Effect of N-Terminal Glutamic Acid and Glutamine on Fragmentation of Peptide Ions

March 27, 2010
Author(s)
Bhaskar Godugu, Pedatsur Neta, Yamil Simon, Stephen Stein
… exception of peptides containing glutamine or glutamic acid at the N-terminus. To elucidate the mechanism by which … mass spectrometer. Loss of water from N-terminal glutamic acid and glutamine is observed at a lower voltage than any … by examining peptides with N-terminal pyroglutamic acid and N-acetyl peptides. Peptides with N-terminal proline …

The role of indoor surface pH in controlling the fate of acids and bases in an unoccupied residence

February 26, 2024
Author(s)
Jenna Ditto, Marc Webb, Han Huynh, Jie Yu, Glenn Morrison, Barbara Turpin, Michael Alves, Kathryn Mayer, Michael Link, Allen Goldstein, Dustin Poppendieck, Marina Vance, Delphine Farmer, Arthur Chan, Jonathan Abbatt
… surface basicity on the fate of gaseous and particulate acids and bases in an unoccupied house. In response to … cooking experiments, which represent realistic sources of acids and bases to the indoor environment but which emit 10 … ammonia, surface-associated water, acids, bases …

Controlled Mixing: An in situ Hybridization Assay of Peptide Nucleic Acids with DNA by Temperature Gradient Focusing

October 16, 2008
Author(s)
K M. Balss, David J. Ross, H Begley, K G. Olsen, Michael J. Tarlov
… acid hybrdization assay involving DNA and peptide nucleic acids (PNAs) employs temperature gradient focusing to … concentration method, mixing, peptide nucleic acids (PNA), separations … Mixing: An in situ Hybridization Assay of Peptide Nucleic Acids with DNA by Temperature Gradient Focusing …

CCQM-K142 Comparison of CRMs and Value-Assigned Quality Controls: Urea and Uric Acid in Human Serum or Plasma

March 21, 2019
Author(s)
David L. Duewer, Katrice A. Lippa, Blaza Toman, Tang Lin Teo, Qinde Liu, Pui Sze Cheow
… of CRMs and Value-Assigned Quality Controls: Urea and Uric Acid in Human Serum or Plasma” is the third Key … materials (CRMs). CRMs certified for urea and/or uric acid content in human serum or plasma were compared using … urea; five NMIs/DIs submitted 12 CRMs certified for uric acid. These materials represent most of the higher-order …

Parameterizing modified nucleic acids for molecular simulations in the AMBER MD software environment

January 6, 2026
Author(s)
Olivia Love, Rodrigo Galindo-Murillo, Daniel Roe, Pablo D. Dans, Thomas E. Cheatham III, Akanksha Manghrani, Christina Bergonzo
… Parameterizing modified nucleic acids is a difficult but necessary task for expanding the … necessary to perform parameterization of modified nucleic acids using modXNA. … molecular dynamics, force fields, modified nucleic acids … Parameterizing modified nucleic acids for molecular simulations in the AMBER MD software …

Proteomic and Lipidomic Plasma Evaluations Reveal Biomarkers for Domoic Acid Toxicosis in California Sea Lions

November 24, 2024
Author(s)
Amie Solosky, Iliana Claudio, Kaylie Kirkwood, Jessie Chappel, Michael Janech, Alison Bland, Frances Gulland, Benjamin Neely, Erin Baker
… Domoic acid is a neurotoxin secreted by the marine diatom genus … sea lions (Zalophus californianus) are exposed to domoic acid through the ingestion of fish that feed on toxic diatoms, resulting in domoic acid toxicosis (DAT), which can vary from mild to fatal. Sea …

Standard Reference Material 2378 Fatty Acids in Frozen Human Serum. A Clinical SRM based on Endogenous Supplementation of Polyunsaturated Fatty Acids

February 13, 2018
Author(s)
Bruce A. Benner Jr., Michele M. Schantz, Johanna Camara, Katherine E. Sharpless, James H. Yen, Lorna T. Sniegoski, Carissa D. Powers, Rosemary L. Schleicher
… Dietary fatty acids can be both beneficial and detrimental to human health … of Dietary Supplements are interested in circulating fatty acids (FAs) because they may be predictive of coronary heart … assigned for analytes of clinical interest. SRM 2378 Fatty Acids in Frozen Human Serum was introduced in 2015 to help …

Analysis of Potential Homemade Nitrate Ester Explosive By-products via Direct Analysis in Real Time Mass Spectrometry

December 9, 2015
Author(s)
Edward Sisco, Thomas Forbes
… (DART-MS) to detect five representative homemade nitrate ester explosive by-products. Instrumental parameters that … and sensitive method for the screening of homemade nitrate ester explosives and by-products, building upon previous results for the detection of nitrate ester explosives and their corresponding sugar alcohol …

Effect of Polymer Molecular Weight on the Adsorption of Polyacrylic Acid at the Alumina-Water Interface

November 1, 1998
Author(s)
D Santhiya, G Nandini, K A. Natarajan, S G. Malghan
… of alumina suspensions in the presence of polyacrylic acid as a dispersant have been studied. The adsorption … mechanisms of interaction between alumina and polyacrylic acid are discussed. … chemical interaction, hydrogen bonding, PAA, polyacrylic acid … Polymer Molecular Weight on the Adsorption of Polyacrylic Acid at the Alumina-Water Interface …

High-Throughput Screening of Cell Proliferation on Poly(L-lactic acid)/Poly(D,L-lactic acid) Blends

January 1, 2005
Author(s)
Carl Simon Jr., Naomi Eidelman, Scott B. Kennedy, Amit Sehgal, C A. Khatri, N. R. Washburn
… A gradient in polymer blend composition of poly(L-lactic acid) (PLLA) and poly(D,L-lactic acid) (PDLLA) was created in the form of a strip-shaped film … FTIR microspectroscopy, high-throughput assay, poly(lactic acid), polymer … Screening of Cell Proliferation on Poly(L-lactic acid)/Poly(D,L-lactic acid) Blends …

Unexpected Gas-Phase Nitrogen-Oxygen Smiles Rearrangement: CID of Deprotonated 2-(N-Methylanilino)ethanol and Morpholinylbenzoic Acid Derivatives

October 21, 2022
Author(s)
Yuxue Liang, Yamil Simon, Pedatsur Neta, Stephen E. Stein
… rearrangement also occurs for various morpholinylbenzoic acid derivatives with a multistep mechanism, where the … 2-(N-Methylanilino)ethanol, morpholinylbenzoic Acid, analysis, chemical analysis, chemical databases, … 2-(N-Methylanilino)ethanol and Morpholinylbenzoic Acid Derivatives …

Effects of Desialylation on Human alpha1-Acid Glycoprotein-Ligand Interactions

September 16, 2013
Author(s)
Richard Y. Huang, Jeffrey W. Hudgens
… Human α1-Acid Glycoprotein (AGP), an acute phase glycoprotein, exists … dynamics induced by the removal of terminal sialic acid. HDX-MS also reveals the changes in conformational … AGP, glycoprotein, human alpha1-acid, hydrogen/deuterium exchange, mass spectrometry, …

Acid-Assisted Consolidation of Powder Compacts: Cold-Welding or Cold Sintering

June 1, 1999
Author(s)
M P. Dariel, M Ratzker, F Eichmiller
… Silver powder that has been treated in dilute fluoroboric acid solution and compacted at room temperature displays … effect of silver in the presence of the fluoroboric acid, acting as a fluxing agent, or as cold liquid-phase … acid-assisted consolidation, cold sintering, cold welding, …
Displaying 76 - 100 of 1412
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