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Yannic Ramaye, Vikram Kestens, J. Charoud-Got, S. Mazoua, G. Auclair, Tae Joon Cho, Blaza Toman, Vincent A. Hackley, T. Linsinger
This report describes the production of ERM-FD306/SRM 1993, silica nanoparticles suspended in a borate buffer, certified for electrophoretic mobility and zeta potential measurements. This material was produced following ISO Guide 17034:2016 and is
Lee L. Yu, Karen E. Murphy, Colleen E. Bryan Sallee, Thomas W. Vetter, Robert C. Hagwood, George C. Caceres, Stephen E. Long, J M. Jarrett, M A. Franklin, J Castro Georgi, D M. Jones, Robert Jones, Z Li, Y L. Sommer, D S. Tevis, K Wallon, C D. Ward, M Maras, S Erdahl, C Gilmer, M Wermers, H Woldeysus, K F. Mehigan, M Morrissette, Christopher D. Palmer, Patrick J. Parsons
Standard Reference Material (SRM) 955d is intended for use in validating analytical methods for measuring toxic elements and mercury species in human blood, and in value assigning locally produced control materials analyzed using the validated methods. A
Justin M. Zook, Justin M. Wagner, Chen-Shan Chin, Qiandong Zeng, Alexander Dilthey, Tobias Marschall, Mikko Rautiainen, Erik Garrison, Shilpa Garg
Most human genomes are characterized by aligning individual reads to the reference genome, but accurate long reads and linked reads now enable us to construct accurate, phased de novo assemblies. We focus on a medically important, highly variable, 5
The Dictionary of Algorithms and Data Structures (DADS) is a publicly accessible dictionary of generally useful algorithms, data structures, algorithmic techniques, archetypal problems, and related definitions available at https://nist.gov/DADS/. DADS is
Huong Giang T. Nguyen, Christopher M. Sims, Blaza Toman, Jarod C. Horn, Roger D. van Zee, Mathias Thommes, Riaz Ahmad, Joeri F. Denayer, Gino V. Baron, Emilio Napolitano, Marek Bielewski, Enzo Mangano, Stefano Brandani, Broom Darren, M.J. Benham, Anne Dailly, Frieder Dreisbach, Satyannarayana Edubilli, Sasidhar Gumma, Jens Mollmer, Marcus Lange, Mi Tian, Tim Mays, T. Shigeoka, S. Yamakita, M. Hakuman, Y. Nakada, K. Nakai, Junyoung Hwang, Ronny Pini, Huan Jiang, Armin Ebner, Marjorie Nicholson, James Ritter, Judit Farrando Perez, Carlos Cuadrado, Joaquin Silvestre Albero, Christos Tampaxis, Theodore Steriotis, Daniela Rimnacova, Martina Svabova, Maryna Vorokhta, Hai Wang, Eric Bovens, Nicolas Heymans, Guy de Weireld
This paper reports the results of an international interlaboratory study led by the National Institute of Standards and Technology (NIST) on the measurement of high-pressure surface excess methane adsorption isotherms on NIST Reference Material RM 8850
This document is a companion of NIST Special Publication 260-136 (2020 Edition), intended for users of NIST reference materials, that explains how NIST evaluates and expresses measurement uncertainty associated with certified or with non-certified values
Debra L. Ellisor, William C. Davis, Rebecca S. Pugh
Biological reference materials (RMs) are essential for quality assurance, traceability of measurement results and for method validation. When addressing new measurement questions or emerging regulatory issues, rigorous large-scale CRM production may not be
Carlos R. Beauchamp, Johanna Camara, Jennifer Carney, Steven J. Choquette, Kenneth D. Cole, Paul C. DeRose, David L. Duewer, Michael Epstein, Margaret C. Kline, Katrice Lippa, Enrico Lucon, Karen W. Phinney, Maria Polakoski, Antonio Possolo, Katherine E. Sharpless, John R. Sieber, Blaza Toman, Michael R. Winchester, Donald Windover
The National Institute of Standards and Technology (NIST), formerly the National Bureau of Standards, was established by the U.S. Congress in 1901 and charged with establishing a measurement foundation to facilitate U.S. and international commerce. NIST
Frank W. DelRio, May L. Martin, Raymond L. Santoyo, Enrico Lucon
Background: About ten years ago, super-high energy Charpy specimens at the National Institute of Standards and Technology were removed from inventory due to unacceptable variability in absorbed energy, leading to the advent of new methods and materials to
Justin Zook, Nathanael David Olson, Marc Salit, Fritz Sedlazeck
New technologies and analysis methods are enabling genomic structural variants (SVs) to be detected with ever-increasing accuracy, resolution and comprehensiveness. To help translate these methods to routine research and clinical practice, we developed a
Justin M. Zook, Justin M. Wagner, Nathanael D. Olson, Steven L. Salzberg, Alaina Shumate, Aleksey V. Zimin, Daniela Puiu, Mihaela Pertea, Marc Salit
Thousands of experiments and studies use the human reference genome as a resource each year. This single reference genome, GRCh38, is a mosaic created from a small number of individuals, representing a very small sample of the human population. There is a
David R. Black, Marcus Mendenhall, Albert Henins, James Filliben, James Cline
The National Institute of Standards and Technology (NIST) certifies a suite of Standard Reference Materials (SRMs) to be used to evaluate specific aspects of instrument performance of both X-ray and neutron powder diffractometers. This report describes SRM
Digital polymerase chain reaction (dPCR) methodology has been asserted to be a "potentially primary" analytical approach for assigning DNA concentration. Currently available chamber dPCR (cdPCR) and droplet dPCR (ddPCR) platforms are thought capable of
Melissa M. Phillips, David M. Bunk, Carlos A. Gonzalez, Scott A. Jackson, Leah R. Kauffman, Katrice A. Lippa, Catherine A. Rimmer, Stephen Semancik, Michael R. Winchester, Laura J. Wood
John R. Sieber, John L. Molloy, Nathanael A. Heckert
The National Institute of Standards and Technology has issued its first Standard Reference Materials for elemental analysis of polyvinyl chloride. The custom designed PVC blends contain elements regulated in consumer products by the United States, the
Working with industry labs quickly introduces one to activities of standard development organizations, who publish test methods, and accrediting bodies, who audit labs for compliance with ISO/IEC 17025, and industry specific quality system requirements
Steven J. Choquette, David L. Duewer, Katherine E. Sharpless
The National Institute of Standards and Technology (NIST), formerly the National Bureau of Standards, was established by the U.S. Congress in 1901 and charged with establishing a measurement foundation to facilitate U.S. and international commerce. This
Ashley B. Green, David M. Bunk, Nien F. Zhang, Wendell Alejo
This Standard Reference Material (SRM) is intended primarily for use in the preparation of calibration solutions for a candidate reference measurement procedure for human serum albumin (HSA) in human urine. This candidate reference measurement procedure is
Lisa E. Kilpatrick, Ashley S. Boggs-Russell, William C. Davis, Stephen E. Long, James H. Yen, Karen W. Phinney
Previous reports have shown that vitamin D-binding protein (VDBP) concentrations increase with gestational age and reference ranges have been suggested for each trimester. However, these studies used immunoassays which may result in variations between
Jeremie Parot, Arnab K. Mukherjee, Martin Couillard, Maohui Chen, Shan Zou, Vincent A. Hackley, Linda Johnston
Cellulose nanocrystals derived from various types of cellulose biomass have significant potential for applications that take advantage of their availability from renewable natural resources and their high mechanical strength, biocompatibility and ease of
Tang Lin Teo, Katrice Lippa, Lindsey Mackay, Sharon Yong, Qinde Liu, Johanna Camara, Vincent Delatour, Tong Kooi Lee, Beatrice Lalere, Gavin O'Connor, Andr? Henrion, Megumi Kato, Jane L. Fernandes, Masahiko Numata, Ha-Jeong Kwon, Ji-Seon Jeong, Bei Xu, Jintana Nammoommoy, Dewei Song, Wagner Wollinger
Over two decades, the Organic Analysis Working Group (OAWG) of the Consultative Committee for Amount of Substance (CCQM) has organised a number of comparisons for clinically relevant small molecule organic biomarkers. These comparisons are hinged upon the
M. L. De Leoz, David L. Duewer, Scientists Multiple, Stephen E. Stein
Glycosylation is a topic of intense current interest in the development of biologic drugs since it is related to drug safety and efficacy. This work describes results of an interlaboratory study on the glycosylation of NISTmAb, a monoclonal antibody
Katrice Lippa, David L. Duewer, Michael Nelson, Stephen Davies, Lindsey Mackay
Metrological traceability for organic measurements is a documented unbroken chain of calibrations with stated uncertainties that link the chemical result for a sample and a measurement procedure to a primary calibrator in appropriate SI units (e.g., mass
Craig R. Copeland, Bojan R. Ilic, Samuel M. Stavis
We study the experimental variation of a localization microscope due to temporal and thermal factors, enabling elucidation of the discrepancy between transillumination brightfield and epi-illumination fluorescence of an aperture array for magnification