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Certification of Standard Reference Material® 955d, Toxic Elements and Metabolites in Frozen Human Blood



Lee L. Yu, Karen E. Murphy, Colleen E. Bryan Sallee, Thomas W. Vetter, Robert C. Hagwood, George C. Caceres, Stephen E. Long, J M. Jarrett, M A. Franklin, J Castro Georgi, D M. Jones, Robert Jones, Z Li, Y L. Sommer, D S. Tevis, K Wallon, C D. Ward, M Maras, S Erdahl, C Gilmer, M Wermers, H Woldeysus, K F. Mehigan, M Morrissette, Christopher D. Palmer, Patrick J. Parsons


Standard Reference Material (SRM) 955d is intended for use in validating analytical methods for measuring toxic elements and mercury species in human blood, and in value assigning locally produced control materials analyzed using the validated methods. A unit of SRM 955d consists of six vials of frozen human blood with two vials at each of three mass concentration levels. Each vial contains nominally 1.6 mL of whole blood. This publication documents the production, analytical measurements, and statistical evaluations leading to the certification of the SRM.
Special Publication (NIST SP) - 260-206
Report Number


Human blood, Standard Reference Material (SRM), Arsenic (As), Cadmium (Cd), Chromium (Cr), Cobalt (Co), Lead (Pb), Manganese (Mn), Mercury (Hg), Selenium (Se), Uranium (U), Ethylmercury (EtHg), Inorganic Mercury (iHg), Methylmercury (MeHg), Thyroglobulin (Tg), Blood spot testing


Yu, L. , Murphy, K. , Bryan, C. , Vetter, T. , Hagwood, R. , Caceres, G. , Long, S. , Jarrett, J. , Franklin, M. , Castro, J. , Jones, D. , Jones, R. , Li, Z. , Sommer, Y. , Tevis, D. , Wallon, K. , Ward, C. , Maras, M. , Erdahl, S. , Gilmer, C. , Wermers, M. , Woldeysus, H. , Mehigan, K. , Morrissette, M. , Palmer, C. and Parsons, P. (2020), Certification of Standard Reference Material® 955d, Toxic Elements and Metabolites in Frozen Human Blood, Special Publication (NIST SP), National Institute of Standards and Technology, Gaithersburg, MD, [online], (Accessed June 25, 2024)


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Created October 14, 2020, Updated October 15, 2020