NOTICE: Due to a lapse in annual appropriations, most of this website is not being updated. Learn more.

Form submissions will still be accepted but will not receive responses at this time. Sections of this site for programs using non-appropriated funds (such as NVLAP) or those that are excepted from the shutdown (such as CHIPS and NVD) will continue to be updated.

U.S. flag

An official website of the United States government

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

Nanotechnology

Nanobiotechnology

Search Publications

Search Title, Abstract, Conference, Citation, Keyword or Author
  • Published Date
Displaying 51 - 75 of 141

Structural Insights into DNA-Stabilized Silver Clusters

May 10, 2019
Author(s)
Danielle Schultz, Robert G. Brinson, Fahriye N. Sari, Jeffrey Fagan, Christina Bergonzo, Nancy Lin, Joy Dunkers
The structure and dynamics of Ag complexes derived from single stranded DNA (ssDNA) is less understood than their double stranded (dsDNA) counterparts despite their great promise as fluorescent biological probes and sensors. In this work, we seek new

Bridging communities in the field of nanomedicine

April 30, 2019
Author(s)
Blanka Halamoda-Kenzaoui, Simon Baconnier, Thierry Bastogne, Didier Bazile, Patrick Boisseau, Gerrit Borchard, Sven E. Borgos, Luigi Calzolai, Karin Cederbrant, Gabriella di Felice, Tiziana Di Francesco, Marina Dobrovolskaia, Rog?rio Gaspar, Bel?n Gracia, Vincent A. Hackley, Lada Leyens, Neill Liptrott, Margriet Park, Anil Patri, Gert Roebben, Matthias Roesslein, Ren? Th?rmer, Patricia Urb?n L?pez, Val?rie Zuang, Susanne Bremer-Hoffmann
The workshop "Bridging communities in the field of nanomedicine" was hosted by the European Commission Joint Research Centre on 27-28 September 2017. It gathered experts from regulatory bodies, research institutions and industry to discuss the main

Strategies for robust and accurate measurement of nanomaterial bioaccumulation

April 17, 2019
Author(s)
Elijah J. Petersen, Monika Mortimer, Robert Burgess, Richard Handy, Shannon Hanna, Kay Ho, Monique E. Johnson, Susana Louriero, Selck Henriette, Janeck Scott-Fordsmand, David Spurgeon, Jason Unrine, Nico van den Brink, Ying Wang, Jason White, Patricia Holden
One of the key components for environmental risk assessment of engineered nanomaterials (ENMs) is data on bioaccumulation potential. Accurately measuring bioaccumulation can be critical for regulatory decision making regarding material hazard and risk, and

Highly mechanosensitive ion channels from graphene-embedded crown ethers

November 26, 2018
Author(s)
Alta Y. Fang, Kenneth Kroenlein, Demian Riccardi, Alexander Smolyanitsky
The ability to tune ionic permeation across nanoscale pores profoundly impacts diverse fields from nanofluidic computing to drug delivery. Here, we take advantage of complex formation between crown ethers and dissolved metal ions to demonstrate graphene

A Comparison Between The Solution Properties of Knotted Ring and Star Polymers

October 31, 2018
Author(s)
Luis F. Vargas Lara, Beatriz Pazmino, Jack F. Douglas
We computationally investigate the solution properties of knotted flexible ring and star polymers by combining molecular dynamics simulation (MD) and path-integral calculations. In particular, we consider knotted rings having a minimal crossing number mc

Determination of polypeptide conformation in water with nanoscale resolution in water

July 24, 2018
Author(s)
Georg Ramer, Francesco Ruggeri, Aviad Levin, Toumas Knowles, Andrea Centrone
The conformational structure and folding of proteins are central to many biological processes. However, misfolding of proteins and peptides can lead to toxic aggregates that are involved in Alzheimer’s and other neurodegenerative disorders. Methods to

A Spin-1 Representation for Dual-Funnel Energy Landscapes

July 20, 2018
Author(s)
Justin E. Elenewski, Kirill Velizhanin, Michael P. Zwolak
The interconversion between left- and right-handed helical folds of a polypeptide defines a dual-funneled free energy landscape. In this context, the funnel minima are connected through a continuum of unfolded conformations, evocative of the classical

Aqueous Ion trapping and transport in graphene-embedded 18-crown-6 ether pores

June 25, 2018
Author(s)
Alexander Smolyanitsky, Eugene Paulechka, Kenneth Kroenlein
Using extensive room-temperature molecular dynamics simulations, we investigate selective aqueous cation trapping and permeation in graphene-embedded 18-crown-6 ether pores. We show that in the presence of suspended water-immersed crown-porous graphene, K+

Enhancing optical microscopy illumination to enable quantitative imaging

March 18, 2018
Author(s)
Emil Agocs, Ravikiran Attota
There has been an increasing push to derive quantitative measurements using optical microscopes. While several aspects of microscopy have been identified to enhance quantitative imaging, non- uniform angular illumination asymmetry (ANILAS) across the field

Quantification of DNA/SWCNT Solvation Differences by Aqueous Two Phase Separation

January 8, 2018
Author(s)
Ming Zheng, Yoona Yang, Akshaya Shankar, Thibault Aryaksama, Anand Jagota
Single wall carbon nanotubes (SWCNTs) coated with single-stranded DNA can be effectively separated into various chiralities using an aqueous two phase (ATP) system. Partitioning is driven by small differences in the dissolution characteristics of the

PEGylation of zinc nanoparticles amplifies their ability to enhance olfactory responses to odorant

December 20, 2017
Author(s)
Melissa Singletary, Samantha Hagerty, Shinichiro Muramoto, Yasmine Daniels, William A. MacCrehan, Gheorghe Stan, June W. Lau, Oleg Pustovyy, Ludmila Globa, Edward E. Morrison, Iryna Sorokulova, Vitaly Vodyanoy
Responses of olfactory sensory neurons to odorants are intensely enhanced with the addition of small endogenous and engineered zinc nanoparticles, as shown by physiological experiments. The highest enhancement was recorded with 1.2 nm non-oxidized zinc

Spatial Distribution of Hydrophobic Drugs in Model Nanogel-core Star Polymers

December 5, 2017
Author(s)
Vivek M. Prabhu, Guangmin Wei, Robert D. Miller, Victoria A. Piunova, William Swope, Amber Carr
Star polymers with a cross-linked nanogel-core are promising carriers of cargo for therapeutic applications due the synthetic control of amphiphilicity of arms and the stability to infinite dilution. Three nanogel-core star polymers were investigated to

Nanowire Aptasensors for Electrochemical Detection of Cell-Secreted Cytokines

October 9, 2017
Author(s)
Ying Liu, Ali Rahimian, Sergiy Krylyuk, Tam Vu, Bruno Crulhas, Gulnaz Stybayeva, Dong-Sik Shin, Albert Davydov, Alexander Revzin, Meruyert Imanbekova
Cytokines are small proteins secreted by immune cells in response to pathogens/infections; therefore these proteins can be used in diagnosing infectious diseases. For example, release of a cytokine interferon (IFN)-γ from T-cells is used for blood-based

A Low Energy Route to DNA-wrapped Carbon Nanotubes via Replacement of Bile Salts

August 31, 2017
Author(s)
Ming Zheng, Jason K. Streit, Jeffrey A. Fagan
DNA-wrapped carbon nanotubes are a class of bio-nano hybrid molecules that exhibit extended bonding structures and have enabled carbon nanotube sorting, controlled assembly, and biosensing and bioimaging applications. The current method of synthesizing

MOSAIC: A Modular Single Molecular Analysis Interface for Decoding Multi-state Nanopore Data

October 31, 2016
Author(s)
Jacob H. Forstater, Kyle Briggs, Joseph W. Robertson, Jessica H. Benjamini, Olivier M. Marie-Rose, Canute I. Vaz, John J. Kasianowicz, Vincent Tabard-Cossa, Arvind Balijepalli
Single molecule measurements with nanometer-scale pores are being developed for a wide range of diagnostic and therapeutic applications.  Critical to the method is the ability to accurately and precisely detect the presence of an analyte, quantify its

Functionalized MoS2 nanorribon as a capacitive displacement sensor for DNA sequencing

September 13, 2016
Author(s)
Alex Smolyanitsky, Tsjerk A. Wassenaar, Eugene Paulechka, Kenneth Kroenlein
We propose an aqueous functionalized molybdenum disulfide nanoribbon suspended over a solid electrode as a capacitive displacement sensor aimed at determining the DNA sequence. The detectable sequencing events arise from the combination of Watson–Crick
Was this page helpful?