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Clinical Quality Assurance Program


The National Institute of Standards and Technology (NIST) established a Clinical Quality Assurance Program (ClinQAP) to support the measurement needs of the clinical community. The ClinQAP provided three comparability improvement programs that focused on specific classes of analytes in human serum and plasma matrices.  The ClinQAP concluded in 2017, and parts of the ClinQAP community will now be served through the HAMQAP.


The Micronutrients Measurement Quality Assurance Program (MMQAP) was established in 1984 and provided comparability studies for laboratories that measure vitamins and carotenoids. The Vitamin D Metabolites Quality Assurance Program (VitDQAP) was initiated in 2009 as a collaboration with the National Institutes of Health Office of Dietary Supplements (NIH-ODS). Interlaboratory comparison studies of the VitDQAP were directed toward the measurement of 25-hydroxyvitamin D2, 25-hydroxyvitamin D3, and 3-epi-25-hydroxyvitamin D3 in selected serum and plasma matrices as well as method-appropriate control materials. Finally, the Fatty Acids in Human Serum and Plasma Quality Assurance Program (FAQAP) was established in 2012 to improve the comparability of fatty acids measurements and was also a collaboration with the NIH-ODS. In addition to providing comparability improvement programs, the ClinQAP also interacted with the measurement community to determine the emerging measurement challenges and provides interlaboratory assessments, as needed, to evaluate additional analytes and matrices.


If you are interested in learning more about current programs or providing feedback, please e-mail to hamqap [at] (HAMQAP).

Created January 6, 2014, Updated May 22, 2018