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Arvind Balijepalli (Fed)

Project Leader

Dr. Balijepalli is a Project Leader in the Physical Measurement Laboratory at the National Institute of Standards and Technology (NIST). He received his Ph.D. at the University of Maryland, College Park. He joined NIST after completing a joint National Research Council postdoctoral fellowship between NIST and the National Institutes of Health. At NIST, he develops new chip-scale sensing techniques to enable measurements of fundamental biophysical phenomenon at multiple scales ranging from biomolecular interactions of proteins, nucleic acids and small molecules to measurements of dynamics in cell and tissue mimics.


Electronic Biophysical Measurements


Please contact Dr. Arvind Balijepalli at arvind.balijepalli [at] (arvind[dot]balijepalli[at]nist[dot]gov) to inquire about postdoctoral and collaborative opportunities.

Postdoctoral opportunities are available through a National Research Council (NRC) Fellowship, a 2-year program with application deadlines of February 1 and August 1 each year.

Additional information about the specific opportunities and the program are below:


High-performance dual-gate graphene pH sensors

Son Le, Seulki Cho, Alexander Zaslavsky, Curt A. Richter, Arvind Balijepalli
High precision biophysical measurements that are portable and performed without prior labeling of the molecules can greatly benefit several areas of

Diffusion-limited reactions in nanoscale electronics

Ryan Evans, Arvind Balijepalli, Anthony J. Kearsley
To quantify interactions between drug molecules and target receptors, a novel nanoscale electronics instrument is under development. The instrument consists of

Patents (2018-Present)

Closed-loop Controlled Chemical Apparatus

NIST Inventors
Arvind Balijepalli , Curt A. Richter and Son T. Le
A closed-loop controlled chemical apparatus includes: a compound sensor including: an analyte sensor and that: produces, by the analyte sensor, a voltage signal; a reference sensor in electrical communication with the analyte sensor; a transistor including a gate terminal such that a drain current

Agile Nucleic Acid Sensor And Measuring A Biomarker

NIST Inventors
Kevin Kiesler , Alokik Kanwal , Anthony J. Kearsley , Erica Romsos , Peter M. Vallone , Jacob Majikes and Arvind Balijepalli
An agile nucleic acid sensor includes: a DNA switch; an analysis substrate in electrostatic communication with the DNA switch and that produces a biomarker electrical signal; a transduction member that receives the biomarker electrical signal and produces a transduction signal; a sensor counter

Charge Detector And Process For Sensing A Charged Analyte

NIST Inventors
Arvind Balijepalli and Curt A. Richter
A charge detector includes: a charge sensor that senses a charged analyte and produces a charge signal in response to contact with the charged analyte; a transducer in electrical communication with the charge sensor and that: receives the charge signal from the charge sensor, receives a feedback

DNA Nanotechnology-Based Biomarker Measurement Platform

NIST Inventors
Arvind Balijepalli and Jacob Majikes
We developed a new approach that utilizes the precise addressability of DNA nanotechnology constructs to allow quantitative biomolecule sensing with high sensitivity, specificity and reproducibility. Novel approaches to engineering DNA nanostructures allow the realization of tunable gain elements
Created March 12, 2019, Updated December 8, 2022