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Physical Measurement Laboratory

Microsystems and Nanotechnology Division

Patents

Searches Patent Title, Abstract, Body, Technology Type, and NIST Inventors
Displaying 1 - 19 of 19

Nucleic Acid Nanostructures

NIST Inventors
Jacob Majikes and Veronika Szalai
Embodiments of the present invention relate to methods and composition of a nucleic acid tile with addressable locations for placement of molecular species that can function as sensors, reporters, or enhancers of measurement systems. Embodiments of the present invention may also include a nucleic

Thin Film Magnetic Magnitude Sensor

NIST Inventors
David Gundlach , Emily Bittle and Sebastian Engmann
A novel magnetic field sensor (MFS) may be created with an organic light emitting diode (OLED) made from an organic semiconductor material and an organic photodetector (OPD) built directly on top (or below) of the OLED, wherein one layer is made from a magnetically isotropic material, and which

Optomechanical Ultrasound Detector And Performing Ultrasound Imaging

NIST Inventors
David Long , Thomas W. LeBrun and Jason J. Gorman
An optomechanical ultrasound detector includes: a micromirror substrate; a mechanical resonator that receives ultrasound waves, oscillates at resonator frequency f.sub.r, changes cavity length L.sub.c, and produces intra-cavity light; and an optical microcavity between the micromirror substrate and

Optoelectromechanical Switch And Programming An Optical Network

NIST Inventors
Vladimir Aksyuk and Henri Lezec
Disclosed is an optoelectromechanical switch that includes: an optical feedline disposed on an isolation substrate that receives resonator light that is subject to optical communication to a resonator when a cavity length of the resonator supports an electromagnetic mode at the wavelength of the

Body Cube And Process For Culturing Tissue

NIST Inventors
Mandy Esch
A body cube for culturing tissue that includes: an organ chip holder; and a body barrier chip and a first body organ chip disposed in the organ chip holder, the first body organ chip including a first cell culture chamber that receives cell culture medium and produces a first tissue in the first

Low-loss Metasurface Optics For Deep UV

NIST Inventors
Henri Lezec and Wenqi Zhu
High-performance optical-metasurface-based components configured to at frequencies of UV light and, in particular, in deep UV range and performing multiple optical-wavefront-shaping functions (among which there are high-numerical-aperture lensing, accelerating beam generation, and hologram

Closed-loop Controlled Chemical Apparatus

NIST Inventors
Arvind Balijepalli , Curt A. Richter and Son T. Le
A closed-loop controlled chemical apparatus includes: a compound sensor including: an analyte sensor and that: produces, by the analyte sensor, a voltage signal; a reference sensor in electrical communication with the analyte sensor; a transistor including a gate terminal such that a drain current

Single Quantum Emitter Single Photon Source And Producing A Single Photon Stream

NIST Inventors
Marcelo Davanco
A single quantum emitter single photon source produces a single photon stream and includes: a single-mode excitation waveguide that receives a pump light, propagates pump light as resonant excitation light, and produces evanescent excitation light; a separation gap between single-mode excitation

Non-Vacuum, Non-Contact Spinner Wafer Chuck

NIST Inventors
Glenn Holland
A non-vacuum, non-contact spinner wafer chuck including: a basal member including; a fastener receiver that receives a fastener; a chuck collar including: an inner collar wall; and an outer collar wall; and an engagement surface that: receives and engages a wafer; a wafer engagement cam including
Patent description for Critical-Dimension Localization Microscopy

Apparatus for Critical-Dimension Localization Microscopy

NIST Inventors
Samuel M. Stavis and Craig Copeland
Performing critical-dimension localization microscopy includes: subjecting a first dimensional member and a second dimensional member of a reference artifact to critical-dimension metrology, the first and second dimensional members, in combination, including a critical dimension and each

Body Cube And Process For Culturing Tissue

NIST Inventors
Mandy Esch
This invention describes a microphysiologic body cube that holds multiple organ chips and that can be operated with near physiologic amounts of blood surrogate. The invention can be used to culture multiple tissues with near-physiologic amounts of blood surrogate within one systems. Microphysiologic

DNA Nanotechnology-Based Biomarker Measurement Platform

NIST Inventors
Arvind Balijepalli and Jacob Majikes
We developed a new approach that utilizes the precise addressability of DNA nanotechnology constructs to allow quantitative biomolecule sensing with high sensitivity, specificity and reproducibility. Novel approaches to engineering DNA nanostructures allow the realization of tunable gain elements

High-Performance Ultaviolet Optical Elements Based On Metasurface Technology

NIST Inventors
Henri Lezec , Wenqi Zhu and Jessie Zhang
Shrinking conventional optical systems to chip-scale dimensions will benefit custom applications in imaging, displaying, sensing, spectroscopy, and metrology. Towards this goal, metasurfaces — planar arrays of subwavelength electromagnetic structures that collectively mimic the functionality of

Multiplexed Amplitude Modulation Fluorometry

NIST Inventors
Anthony J. Kearsley , Gregory A Cooksey and Paul Patrone
Improving accuracy of cytometers is challenging because optical configuration, flow control methods, and calibration issues make it difficult to characterize geometric factors associated with signal collection. State-of-the-art tools only collect a small solid angle of emitted light, so that minor

Serial Cytometry

NIST Inventors
Gregory A Cooksey , Paul Patrone and Anthony J. Kearsley
Flow cytometers can make thousands of single-cell measurements per second, but the limited ability to quantify uncertainty in individual measurements reduces their effectiveness for characterizing biomarker distributions, discriminating cell populations, and detecting rare events. To facilitate