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The Fluid Metrology Group leads the world in designing and using gas-filled acoustic resonators for measuring the thermodynamic temperature T, the Boltzmann
The use of tissue/organ-on-a-chip systems is limited to endpoint and destructive measurements. Integration of electronic elements in these systems have proven
It is well known that the physical properties of a fluid can change profoundly, and often non-trivially, when placed in a confined environment. Only for the
NIST has taken advantage of recent technological advances to develop polymer microfluidic cell culture systems that provide a level of control over the cellular
In conjunction with NCI/NIH, NIST is developing methods to improve mRNA amplification from small biological samples. Typical sample processing requires
Digital PCR (dPCR) is a method used to quantify nucleic acids (DNA, RNA, cDNA). At NIST we are using microfluidic and emulsion-based dPCR platforms for
In classical molecular simulations, electrostatic contributions to the potential energy are typically accounted for by assigning partial charges to some or all
Applications such as single cell measurements of protein content (e.g., antibodies, surface markers), low analyte concentration (e.g., biomarkers), and
The purpose of this project is to create rheological measurement methods and tools, focused on using minimal fluid volumes, to measure local flow dynamics and
Despite their promise to enable high-throughput science and discovery, microfluidic devices have not yet been broadly adopted. An important missing element in
The Cryogenic Technologies Project has been funded by ONR since FY2005 to measure and model the losses in 4 K regenerators and pulse tubes. These thermal
Microelectromechanical systems (MEMS) are integrated devices with critical applications in sensing, timing, signal processing, and biomedical diagnostics, and
NIST and the University of Colorado have been funded since April, 2006, by DARPA to develop a microcryocooler with a volume less than about 4 cm 3 to cool a
This project develops and applies metrologies and standards for characterizing microstructure and dynamics in advanced functional materials of technological
Overview Capture of carbon dioxide from the air (direct air capture; DAC) combined with energy efficiency and carbon capture, utilization and storage (CCUS)
NIST provides data resources related to adsorption of both gases and liquids on solid adsorbents through the NIST Data Resources for Adsorption Science and
NIST Standard Reference Database 173 Last Update to Data Content: August 2023 DOI: https://doi.org/10.18434/T4M88Q The Standard Reference Simulation Website is
The manufacture of polymeric materials from their raw form into their final useful product occurs under highly non-equilibrium conditions where temperature and
Our goal is to develop combinatorial and high-throughput measurement approaches for rapid characterization of the structure and phase behavior of multicomponent
Energy is one of the most critical problems facing the United States, with technical, economic, and public policy aspects. Our group develops state-of-the-art
Mass spectrometry is an important technique in analytical chemistry, essential in areas including drug development, criminal and agricultural forensics
Our goal is to develop reliable tools and standards for measuring the properties of cells, biomaterials, scaffolds and tissue-engineered constructs. As