As the fields of tissue engineering and regenerative medicine (TERM) transition from a research endeavor to a successful, profitable industry, there is a need for reliable methods to assess product attributes. Regulatory filings contain many different types of measurement data that are used to assess produce quality, safety and efficacy. Mammalian cell measurements, including count, viability and function, are a major part of these. We develop tools and resources for improving the quality of measurements of mammalian cell attributes, including documentary standards at ISO and ASTM, reference materials, test methods, new measurement capabilities and measurement assurance strategies.