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Search Publications by: Edward Sisco (Fed)

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Displaying 51 - 75 of 81

A Multi-Laboratory Investigation of Drug Background Levels

September 9, 2019
Author(s)
Edward R. Sisco, Marcela N. Najarro
Identifying, quantifying, and analyzing the drug background in operational environments such as forensic laboratories is an emerging body of research. Understanding these levels can provide critical information to address issues like occupational exposure

Understanding the Impact of Drug Background Levels in Forensic Laboratories

August 13, 2019
Author(s)
Edward Sisco, Marcela N. Najarro, Amber Burns, Robert Kirkby
As drugs become increasingly potent and analytical instrumentation becomes more sensitive, the need to understand and monitor drug background levels is becoming imperative. Background monitoring is commonplace in many other industries but has been largely

Evaluation of a lateral flow immunoassay for the detection of the synthetic opioid fentanyl

April 26, 2019
Author(s)
Edward Sisco, Daniel J. Angelini, Tracey D. Briggs, Michele N. Maughan, Michael G. Feasel, Jennifer W. Sekowski
In the United States in 2016, 64,000 overdose deaths were reported to be associated with the abuse of opioids, including prescription painkillers (e.g. oxycodone), opiates (e.g. heroin), or synthetic opioids (e.g. fentanyl). The recent spike in the

A Standards and Measurement Infrastructure for Calibration, Verification and Optimization of Trace Explosives Detection Systems

April 15, 2019
Author(s)
John G. Gillen, Jennifer R. Verkouteren, R M. Verkouteren, Marcela N. Najarro, Edward R. Sisco, Matthew E. Staymates, Jessica L. Staymates, Robert A. Fletcher, Jeffrey A. Lawrence, Elizabeth L. Robinson, Alexander T. Bulk, Joseph A. Bennett, Shinichiro Muramoto, Thomas P. Forbes
Current national priorities in homeland security have led to an unprecedented level of utilization of explosives trace detection (ETD) systems for counterterrorism and law enforcement. Despite the widespread deployment of ETD instruments at airports

ASTM E2677: Web-based International Standard on Limit of Detection for Explosive Trace Detectors (and More) - Opioids and Ozone

February 12, 2019
Author(s)
R M. Verkouteren, Nathanael A. Heckert, Stefan D. Leigh, Edward R. Sisco, James E. Norris, Jeffrey A. Lawrence, Amber Burns
The performance characteristics of explosive and narcotic trace detectors are mission-critical to agencies worldwide that are charged with protection of the public, defense for mass transit and infrastructure, and the safety of first responders. Commercial

A Method for Measuring the Quantity of Drugs on Surfaces in a Forensic Laboratory

September 19, 2018
Author(s)
Edward R. Sisco, Marcela N. Najarro, Amber Burns
While background studies have been commonplace in many occupational fields for a long time, attempts to understand the chemical background in forensics labs has been largely understudied. However, given the increasing sensitivity of instrumentation and

Recent Advances in Ambient Mass Spectrometry of Trace Explosives

May 6, 2018
Author(s)
Thomas Forbes, Edward Sisco
Ambient mass spectrometry has evolved rapidly over the past decade, yielding a plethora of platforms and demonstrating scientific advancements across a range of fields from biological imaging to rapid quality control. These techniques have enabled real

Strategies and Considerations for the Trace Detection of Fentalogs

October 26, 2017
Author(s)
Edward Sisco
Fentanyl and fentanyl analogs pose a significant and ever changing threat in the United States as both pure compounds and in complex mixtures. While commonly considered detection techniques require visible amounts of powder (i.e. color tests or GC/MS

DART-MS analysis of inorganic explosives using high temperature thermal desorption

May 4, 2017
Author(s)
Thomas P. Forbes, Edward R. Sisco, Matthew E. Staymates, John G. Gillen
An ambient mass spectrometry (AMS) platform coupling Joule heating thermal desorption (JHTD) and direct analysis in real time (DART) was developed, generating discretely pulsed rapid heating ramps and elevated temperatures for the detection of inorganic

Rapid Detection of Fentanyl, Fentanyl Analogues, and Opioids for on-Site or Laboratory Based Drug Seizure Screening using Thermal Desorption DART-MS and Ion Mobility Spectrometry

April 27, 2017
Author(s)
Edward Sisco, Jennifer R. Verkouteren, Jessica L. Staymates, Jeffrey Lawrence
Fentanyl and fentanyl analogues represent a current and emerging threat in the United States as pure illicit narcotics and as cutting agents with heroin. Because of their extreme potency, methods to safely and rapidly detect these compounds are of high

Standardized Measurements of Collection Efficiency from Wipe-Sampling of Trace Explosives

April 10, 2017
Author(s)
Jennifer R. Verkouteren, Jeffrey A. Lawrence, Matthew E. Staymates, Edward R. Sisco
One of the limiting steps to detecting traces of explosives at screening venues is effective collection of the sample. Wipe-sampling is the most common procedure for collecting traces of explosives, and standardized measurements of collection efficiency

Quantifying Stability of Trace Explosives under Different Environmental Conditions

April 1, 2017
Author(s)
Edward R. Sisco, Marcela N. Najarro, Daniel V. Samarov, Jeffrey A. Lawrence
This work investigates the stability of trace deposits of six explosives (ETN, PETN, RDX, HMX, TNT, and Tetryl) to determine environmental stabilities and lifetimes. Explosives were inkjet printed directly onto PTFE coated fiberglass substrates and exposed

Development of a Chemically Relevant Artificial Fingerprint Material

September 16, 2015
Author(s)
Edward Sisco, Jessica L. Staymates, Katherine Schilling, John Gillen
The development of a chemically relevant artificial fingerprint material as well as a preliminary method for fingerprint deposition is discussed herein. More specifically the improvement of an artificial sweat material, an artificial sebaceous material