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Search Publications by: Carl G. Simon, Jr., Ph.D. (Fed)

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Displaying 226 - 250 of 265

Cell Seeding into Calcium Phosphate Cement

March 1, 2004
Author(s)
Carl Simon Jr., William F. Guthrie, Francis W. Wang
We have sought to improve calcium phosphate cement by developing a method for seeding bone cells into the cement. Calcium phosphate cement (CPC) is a dry white powder of calcium phosphate salts that when mixed with water will react to form microcrystalline

Dynamical Adhesion Force of Cells on Biomaterial Substrates

February 1, 2004
Author(s)
Y N. Deng, Carl Simon Jr., P M. McGuiggan, Sheldon M. Wiederhorn, Brian R. Lawn
The adhesion of cells to synthetic biomaterial implant surfaces is an essential step for tissue growth in bone repair. Such adhesion can mandate whether the tissue will accept or reject the implanted biomaterials. In this study, the adhesion forces between

Combinatorial Screening of Cell-Material Interactions

January 1, 2004
Author(s)
N. R. Washburn, Carl Simon Jr., Michael Weir, L A. Bailey, S B. Kennedy, Eric J. Amis
Tissue engineering applications involve developing materials to guide cellular response in the repair of missing or damaged tissue. We have been developing combinatorial methods for characterizing the functional dependence of cellular responses on material

Imaging Cells on Polymer Spherulites

January 1, 2004
Author(s)
Carl G. Simon Jr.
Polymers are one of the many materials used to fabricate tissue engineered medical products (Ratner et al., 1996). Polymer processing methods, such as how monomers are converted to polymers or how polymers are formed into products, can drastically affect

High-Throughput Investigation of Cell Proliferation on Crystalline Polymers

April 1, 2003
Author(s)
N. R. Washburn, S B. Kennedy, Carl Simon Jr., K Yamada, Eric J. Amis
The results of our investigation of cell proliferation on crystalline polymers will be presented. The goal of the research is to investigate how cells respond to nanometer scale roughness, and crystallizing poly(L-lactic acid) (PLLA) was a convenient

Preliminary Report on the Biocompatibility of a Moldable, Resorbable, Composite Bone Graft Consisting of Calcium Phosphate Cement and Poly (Lactide-Co-Glycolide) Microspheres

May 1, 2002
Author(s)
Carl Simon Jr., C A. Khatri, Scott Wight, Francis W. Wang
We have assessed the biocompatibility of a new composite bone graft consisting of calcium phosphate cement (CPC) and poly(lactide-co-glycolide) (PLGA) microspheres (175-350 ?m) using cell culture techniques. CPC powder is mixed with PLGA microspheres and