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Search Publications by: Dr. Vincent A. Hackley (Fed)

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Displaying 51 - 75 of 153

Potential artifacts and misinterpretations when evaluating the ecotoxicological effects of nanomaterials

June 16, 2014
Author(s)
Elijah J. Petersen, Theodore Henry, Jian Zhao, Robert MacCuspie, Teresa L. Kirschling, Vincent A. Hackley, Baoshan Xing, Jason White
Engineered nanomaterials (ENMs) have significant commercial potential in a broad range of industries for consumer products as a result of their novel properties. However, these same properties may cause unexpected risks once ENMs are released into the

Use of Single Particle Inductively Coupled Plasma Mass Spectrometry to Characterize a New Silver Nanoparticle Reference Material

June 11, 2014
Author(s)
Karen E. Murphy, Jingyu Liu, William F. Guthrie, Justin M. Gorham, John E. Bonevich, Andrew J. Allen, Michael R. Winchester, Vincent A. Hackley, Robert MacCuspie
In this study we use inductively coupled plasma mass spectrometry operated in single particle mode (spICP-MS) to simultaneously characterize the size distribution and dissolved silver fraction of a new silver nanoparticle (AgNP) candidate reference

Potential artifacts when evaluating the ecotoxicological effects of nanomaterials

March 28, 2014
Author(s)
Elijah J. Petersen, Marina Dobrovolskaia, Theodore B. Henry, Jian Zhao, Robert I. MacCuspie, Teresa L. Kirschling, Baoshan Xing, Vincent A. Hackley, Jason White
Engineered nanomaterials (ENMs) have a significant commercial potential for ENM-enable products as a result of novel or enhanced properties. However, the unique behaviors of ENMs may also cause artifacts, spurious results, effects, or findings, when

Highly Stable Positively Charged Dendron-Encapsulated Gold Nanoparticles

March 13, 2014
Author(s)
Tae Joon Cho, Robert I. MacCuspie, Julien C. Gigault, Justin M. Gorham, John T. Elliott, Vincent A. Hackley
We report the development of a novel cationic dendron (TAG1-PCD) and a positively charged gold nanoparticle-dendron conjugate (PCD-AuNP). TAG1-PCD was designed by considering the reactivity, hydrophilicity, and cationic nature that is required to yield a

Controlled Formation and Characterization of Dithiothreitol-Conjugated Gold Nanoparticle Clusters

March 5, 2014
Author(s)
De-Hao D. Tsai, Tae Joon Cho, Frank W. DelRio, Justin Gorham, Jiwen Zheng, Jiaojie Tan, Michael R. Zachariah, Vincent A. Hackley
We report a systematic study of the controlled formation of discrete-size gold nanoparticle clusters (GNCs) by interaction with the reducing agent dithiothreitol (DTT). Asymmetric-flow field flow fractionation and electrospray differential mobility

Saponins: A sustainable surfactant. From its microwave-assisted extraction to the synthesis of monodisperse latices

January 21, 2014
Author(s)
Charlene Schnitt, Bruno Grassl, Julien C. Gigault, Vincent A. Hackley, Gaetane Lespes, Jacques Desbrieres, Virginie Pellerin, Stephanie Reynaud
Synthetic surfactants are widely used in emulsion polymerization, but it is increasingly desirable to replace them with naturally derived molecules with a reduced environmental burden. This study demonstrates the use of saponins as sustainable and

Pulmonary and Cardiovascular Responses of Rats to Inhalation of Silver Nanoparticles

August 14, 2013
Author(s)
Jenny R. Roberts, Walt McKinney, Hong Kan, Kristine Krajnak, David G. Frazer, Treye Thomas, Stacey Waugh, Allison Kenyon, Robert I. MacCuspie, Vincent A. Hackley, Vincent Castranova
Rats were exposed by inhalation to filtered air or to a low (100 ug/m3 using a commercial antimicrobial product [20 mg/L silver]) or high (1000 ug/m3 using a suspension [200 mg/L silver] synthesized to have a similar size distribution) concentration of

Temperature-Programmed Electrospray-Differential Mobility Analysis for Characterization of Ligated Nanoparticles in Complex Media

August 12, 2013
Author(s)
De-Hao D. Tsai, Frank W. DelRio, John M. Pettibone, Pin A. Lin, Jiaojie Tan, Michael R. Zachariah, Vincent A. Hackley
In this study, an electrospray-differential mobility analyzer (ES-DMA) was operated with an aerosol flow-mode, temperature-programmed approach to enhance its ability to characterize the particle size distributions (PSDs) of nanoscale particles (NPs) in the

Just Add Water – reproducible singly dispersed silver nanoparticle suspensions

June 19, 2013
Author(s)
Robert I. MacCuspie, Andrew J. Allen, Matthew N. Martin, Vincent A. Hackley
Silver nanoparticles (AgNPs) are of interest due to their antimicrobial attributes, which are derived from their inherent instability and subsequent release of silver ions into solution. At the same time, this instability makes achieving stable long-term

Differentiation and characterization of isotopically modified silver nanoparticles in aqueous media using asymmetric-flow field flow fractionation coupled to optical detection and mass spectrometry

December 10, 2012
Author(s)
Julien C. Gigault, Vincent A. Hackley
The principal objective of this work was to develop and demonstrate a new methodology for silver nanoparticle (AgNP) detection and characterization based on asymmetric-flow field flow fractionation (A4F) coupled to multiple detectors and using stable

Nanoscale Reference Materials for Environmental, Health, and Safety Measurements: Needs, Gaps, and Opportunities

November 7, 2012
Author(s)
Aleksandr B. Stefaniak, Vincent A. Hackley, Gert Roebben, Kensei Ehara, Steve Hankin, Michael T. Postek, Iseult Lynch, Wei-En Fu, Thomas P. Linsinger, Andreas Th?nemann
There is a need to understand and manage potential risks posed to workers, the public, and the environment from exposure to engineered nanomaterials. In response, several organizations have developed lists of relevant nano-objects and of physico-chemical

Quantifying Dithiothreitol Displacement of Functional Ligands from Gold Nanoparticles

October 27, 2012
Author(s)
De-Hao D. Tsai, Frank W. DelRio, Sherrie R. Elzey, Suvajyoti S. Guha, Michael R. Zachariah, Vincent A. Hackley, Melanie P. Shelton
Dithiothreitol (DTT)-based displacement is widely utilized for separating ligands from their gold nanoparticle (AuNP) conjugates, a critical step for differentiating and quantifying surface-bound functional ligands and therefore the effective surface

Evaluation of viability and proliferation profiles on macrophages treated with silica nanoparticles in vitro via plate-based, flow cytometry, and Coulter counter assays

September 3, 2012
Author(s)
Simona Bancos, De-Hao D. Tsai, Vincent A. Hackley, J L. Weaver, Katherine M. Tyner
Nanoparticles (NPs) are known to interfere with many high throughput cell viability and cell proliferation assays, which complicates the assessment of their potential toxic effects. The aim of this study was to compare viability and proliferation results

Summary Report of Research on TiO2 Nanomaterial

August 3, 2012
Author(s)
Vincent A. Hackley
Report summarizes study whose purpose was to optimize and validate a standardized and reproducible approach for the preparation of TiO2 nanoparticle dispersions in relevant biological and environmental test media, using an industrially relevant powder form