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Search Publications by: Robert N Goldberg (Assoc)

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Displaying 1 - 25 of 91

Enzyme-catalyzed Reactions

May 23, 2016
Author(s)
Robert N. Goldberg
The thermodynamic principles that pertain to both chemical and overall biochemical reactions are discussed with particular emphasis on enzyme-catalyzed reactions. Chemical reactions involve specific species (which may also be biochemical importance) and

A thermodynamic investigation of the cellulose allomorphs: cellulose(am), cellulose I?(cr), cellulose II(cr), and cellulose III(cr)

November 11, 2014
Author(s)
Robert N. Goldberg, Jacob Schliesser, Ashutosh Mittal, Stephen R. Decker, Ana Filipa L. Santos, Vera L. Freitas, Aaron A. Urbas, Brian E. Lang, Christian Heisse, Maria D. Ribeiro da Silva, Brian F. Woodfield, Rui Katahira, Wei Wang, David K. Johnson
The thermochemistry of samples of amorphous cellulose, cellulose I, cellulose II, and cellulose III was studied by using oxygen bomb calorimetry, solution calorimetry in which the solvent was cadoxen, and with a Physical Property Measurement System (PPMS)

Standards in Biothermodynamics

May 15, 2014
Author(s)
Robert N. Goldberg
The field of biothermodynamics encompasses physical property measurements on biochemical and biological systems. This chapter reviews the status of standards documents that are pertinent to biothermodynamics as well as recommendations that have been made

Thermochemistry of alpha-D-xylose(cr)

December 4, 2012
Author(s)
Robert N. Goldberg, Manuel A. Ribeiro da Silva, Maria D. Ribeiro da Silva, Ana I. Lobo Ferreira, Quan Shi, Brian F. Woodfield
The thermochemistry of alpha-D-xylose(cr) was studied by means of oxygen bomb calorimetry and a Physical Property Measurement System (PPMS) in zero magnetic field. The sample of -D-xylose(cr) used in this study was one well-characterized by HPLC, Karl

Introduction to the Special Issue on Biothermodynamics

May 14, 2012
Author(s)
Robert N. Goldberg
In its broadest sense, biothermodynamics encompasses all thermochemical and thermophysical property measurements and calculations on biochemical and biological systems. This makes for an extremely broad field given the large number of properties and the

Saturation molalities and standard molar enthalpies of solution of alpha-D-xylose(cr) in H2O(l); Standard molar enthalpies of solution of 1,4-beta-D-xylobiose(am), and 1,4-beta-D-xylotriose(am) in H2O(l)

May 14, 2012
Author(s)
Robert N. Goldberg, Brian E. Lang, Bruce Coxon, Stephen R. Decker
The saturation molality of alpha-D-xylose(cr) in water was measured by using HPLC and is m(sat) = (8.43 ± 0.42) mol∙kg-1 at the temperature T = 298.15 K. It was also established that the anhydrous form of alpha-D-xylose(cr) is the crystalline form that is

Extension of ThermoML: The IUPAC Standard for Thermodynamic Data Communications (IUPAC Recommendations 2011)

September 7, 2011
Author(s)
Michael D. Frenkel, Robert D. Chirico, Vladimir Diky, Paul L. Brown, John H. Dymond, Robert N. Goldberg, Anthony R. Goodwin, Heiko Heerklotz, Erich Koenigsberger, John E. Ladbury, Kenneth N. Marsh, David P. Remeta, Stephen E. Stein, William A. Wakeham, Peter A. Williams
ThermoML is an XML-based approach for storage and exchange of experimental, predicted, and critically evaluated thermophysical and thermochemical property data. Extensions to the ThermoML schema for the representation of speciation, complex equilibria, and

Recommendations for Terminology and Databases for Biochemical Thermodynamics

April 22, 2011
Author(s)
R Alberty, A. Bowden-Cornish, Robert N. Goldberg, G.G Hammes, K. Tipton, H.V. Westerhoff
Although chemical equations are normally written in terms of specific ionic and elemental species and balance atoms of elements and electric charge, it is usually better in a biochemical context to write them with ionic reactants expressed as totals of

ThermoML an XML-based Approach for Storage and Exchange of Experimental and Critically Evaluated Thermophysical and Thermochemical Property Data. 5. Speciation and Complex Equilibria

January 7, 2011
Author(s)
Michael D. Frenkel, Vladimir Diky, Robert D. Chirico, Robert N. Goldberg, Heiko Heerklotz, John E. Ladbury, David P. Remeta, John H. Dymond, Anthony R. Goodwin, Kenneth N. Marsh, William A. Wakeham, Stephen E. Stein, Paul L. Brown, Erich Koenigsberger, Peter A. Williams
ThermoML is an XML-based approach for storage and exchange of experimental and critically evaluated thermophysical and thermochemical property data. Extensions to the ThermoML schema for the representation of speciation and complex equilibria are described

BioPAX A Community Standard for Pathway Data Sharing

September 9, 2010
Author(s)
Robert N. Goldberg, Michael Cary, Erek Demir
BioPAX (Biological Pathway Exchange) is a standard language to represent biological pathways and processes at the molecular and cellular level. Its major use is to facilitate the exchange of pathway data (http://www.biopax.org). Pathway data captures our

ThermoML an XML-based Approach for Storage and Exchange of Experimental and Critically Evaluated Thermophysical and Thermochemical Property Data. 4. Biomaterials

December 12, 2009
Author(s)
Robert D. Chirico, Michael D. Frenkel, Vladimir Diky, Robert N. Goldberg, Heiko Heerklotz, John E. Ladbury, David P. Remeta, John H. Dymond, Anthony R. Goodwin, Kenneth N. Marsh, William A. Wakeham
ThermoML is an XML-based approach for storage and exchange of experimental and critically evaluated thermophysical and thermochemical property data. Extensions to the ThermoML schema for the representation of properties of biomaterials are described. The

Apparent Equilibrium Constants for Enzyme-catalyzed Reactions

October 1, 2009
Author(s)
Robert N. Goldberg
This table contains values of apparent equilibrium constants K for selected enzyme-catalyzed reactions at specified temperatures T and pHs. In those cases where the ionic strength I and/or the pMg (pMg = log10[Mg2+]) have been reported, the values of

Thermodynamics of the Hydrolysis Reactions of +--D-galactose 1-phosphate, sn-glycerol 3-phosphate, 4 nitrophenyl phosphate, phosphocreatine, and 3-phospho-D-glycerate

May 1, 2009
Author(s)
Robert N. Goldberg, Brian E. Lang, Catherine T. Lo, David J. Ross, Yadu D. Tewari
Microcalorimetry, high-performance liquid chromatography, and an enzymatic assay have been used to conduct a thermodynamic investigation of five phosphate hydrolysis reactions: α-D-galactose 1 phosphate(aq) + H2O(l) = D-galactose(aq) + orthophosphate(aq)

Book Review of Introduction to Modern Thermodynamics

April 6, 2009
Author(s)
Robert N. Goldberg
The book Introduction to Modern Thermodynamics by Dilip Kondepudi (John Wiley & Sons, Hoboken, NJ, 2008, ISBN 978-0-9470-01598-8) is reviewed for Angewandte Chemie.

Thermodynamic Property Values for Enzyme-catalyzed Reactions

August 20, 2008
Author(s)
Robert N. Goldberg
This chapter deals with how one can obtain values of thermodynamic properties specifically the apparent equilibrium constant K, the standard molar transformed Gibbs energy change rG, and the standard molar transformed enthalpy change rH for

A Thermodynamic Study of Ketoreductase-Catalyzed Reactions, Part 5. Reduction of Substituted Ketones in n-Hexane

April 1, 2008
Author(s)
Yadu D. Tewari, David J. Vanderah, Michele M. Schantz, Robert N. Goldberg, J D. Rozzell, J F. Liebman, Raymond W. Hui, Yitzy Nissenbaum, Ahmad R. Parniani
The equilibrium constants K for the ketoreductase-catalyzed reduction reactions of 1-benzyl-3-pyrrolidinone, ethyl 2-oxo-4-phenylbutyrate, ethyl 4-chloroacetoacetate, 1-benzyl-4-piperidone, and 1-benzyl-3-piperidone were measured in n-hexane at T = 298.15

Thermodynamics of Enzyme Catalyzed Reactions: Part 7 - 2007 Update

October 25, 2007
Author(s)
Robert N. Goldberg, Yadu D. Tewari, Talapady N. Bhat
This review serves to update previously published evaluations of equilibrium constants and enthalpy changes for enzyme catalyzed reactions. For each reaction the following information is given: the reference for the data; the reaction studied; the name of

Thermochemistry of Inosine

November 1, 2005
Author(s)
J A. Boerio-Goates, Sarah D. Hopkins, Ricardo A. Monteiro, M D. Ribeiro da Silva, M A. Ribeiro da Silva, Robert N. Goldberg
The formation thermodynamic properties of crystalline and aqueous inosine have been determined by using a combination of calorimetric techniques. Oxygen bomb calorimetric measurements on crystalline inosine yielded a standard molar enthalpy of combustion