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Enzyme-catalyzed Reactions

Published

Author(s)

Robert N. Goldberg

Abstract

The thermodynamic principles that pertain to both chemical and overall biochemical reactions are discussed with particular emphasis on enzyme-catalyzed reactions. Chemical reactions involve specific species (which may also be biochemical importance) and overall biochemical reactions involve substances where one or more of the reactants is a mixture of species. The general principles involved in both equilibrium and calorimetric measurements are discussed with particular emphasis on isothermal microcalorimetry where two solutions are mixed in a reaction vessel. The status of the scientific literature on the thermodynamics of enzyme-catalyzed reactions is summarized along with a discussion of the importance of thermodynamic network calculations on biochemical substances and reactions. The combined use of equilibrium and calorimetric measurements serves as an important tool for elucidating the thermodynamics of the most complex biochemical reactions.
Citation
Biocalorimetry: Foundations and Contemporary Approaches
Publisher Info
Taylor & Francis, Boca Raton, FL

Keywords

calorimetry, enzyme-catalyzed reactions, equilibrium, enthalpy, entropy, Gibbs energy, thermodynamics

Citation

Goldberg, R. (2016), Enzyme-catalyzed Reactions, Taylor & Francis, Boca Raton, FL (Accessed May 22, 2024)

Issues

If you have any questions about this publication or are having problems accessing it, please contact reflib@nist.gov.

Created May 23, 2016, Updated February 19, 2017