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Displaying 126 - 150 of 2345

compareMS2 2.0: An Improved Software for Comparing Tandem Mass Spectrometry Datasets

September 29, 2022
Author(s)
Rob Marissen, Jeroen Laros, Josef Rasinger, Madhushri Varunjikar, Ben Neely, Magnus Palmblad
It has long been known that biological species can be identified from mass spectrometry data alone. Ten years ago, we described a method and software tool, compareMS2, for calculating a distance between sets of tandem mass spectra, as routinely collected

Report from the NIST Workshop: Launch of the Rapid Microbial Testing Methods Consortium

September 27, 2022
Author(s)
Nancy Lin, Scott Jackson, Stephanie Servetas, Kirsten Parratt, Joy Dunkers, Tara Eskandari, Sheng Lin-Gibson
On September 17, 2020, NIST hosted a virtual workshop to launch the Rapid Microbial Testing Methods (RMTM) Consortium. The RMTM Consortium aims to address the need for measurements and standards to increase confidence in the use of rapid testing for

Population data for 94 identity SNPs in four U.S. population groups

September 23, 2022
Author(s)
Kevin Kiesler, Lisa Borsuk, Becky Steffen, Katherine Gettings, Peter Vallone
The U.S. National Institute of Standards and Technology (NIST) sequenced 1036 human DNA samples from four United States population groups (African American, Asian, Hispanic, and Caucasian) using the ForenSeq DNA Signature Prep Kit with Primer Mix B (DPMB)

Mass Spectral Library Methods for Analysis of Site-Specific N-Glycosylation: Application to Human Milk Proteins

September 16, 2022
Author(s)
Concepcion Remoroza, Meghan Burke Harris, Xiaoyu (Sara) Yang, Sergey Sheetlin, Yuri Mirokhin, Sanford Markey, Dmitrii V. Tchekhovskoi, Stephen E. Stein
We present a mass-spectral library-based method for analyzing site-specific N-linked protein glycosylation. Its operation and utility are illustrated by applying it to both newly measured and available proteomics data of human milk glycoproteins. It

Report on the DHS/NIST Workshop on Standards for an Enduring Capability in Wastewater Surveillance for Public Health (SWWS Workshop)

August 16, 2022
Author(s)
Nancy Lin, Stephanie Servetas, Scott Jackson, Katrice Lippa, Kirsten Parratt, Philip Mattson, Clare Beahn, Mia Mattioli, Sally Gutierrez, Michael Focazio, Ted Smith, Paul Storella, Sarah Wright
Wastewater surveillance is a promising approach to monitor biological and chemical contaminants on a community level in support of public health and safety decisions. Wastewater surveillance has recently been shown highly effective for the early detection

Structural Fingerprinting of siRNA Therapeutics by Solution NMR Spectroscopy

August 4, 2022
Author(s)
Owen Becette, Anh Tran, Jace Jones, John Marino, Robert Brinson
Nucleic acids are an increasingly popular platform for the development of biotherapeutics to treat a wide variety of illnesses, including diseases where traditional drug development efforts have failed. To date, there are 14 short oligonucleotide

Effect of Tribologically-Induced Changes in Surface Termination of Silicon-Containing Diamond-Like Carbon Coatings on the Resistance to Biomolecule Adsorption

August 1, 2022
Author(s)
Cherno Jaye, Daniel A. Fischer, Zixuan Li, Jennings Z. Ye, Jieming Yan, Nicolas Molina, Hsu-Ming Lien, Robert Chrostowksi, Jianliang Lin, Mangolini Mangolini
Silicon-containing diamond-like carbon (DLC) is a class of thin-film materials with excellent mechanical properties, high thermal stability, and good tribological performance over a wide range of environmental conditions. While non-alloyed/non-doped DLCs

NMR and Metabolomics -A Roadmap for the Future

July 23, 2022
Author(s)
Tracey Schock, David Wishart, Leo Cheng, Valerie Copie, Arthur Edison, Hamid Eghbalnia, Jeffrey Hoch, Goncalo Gouveia, Wimal Pathmasiri, Robert Powers, Llyod Sumner, Mario Uchimiya
Metabolomics investigates global metabolic alterations associated with chemical, biological, physiological, or pathological processes. These metabolic changes are measured with various analytical platforms. While liquid chromatography-mass spectrometry (LC
Displaying 126 - 150 of 2345