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Displaying 1251 - 1275 of 1510

Copper-binding anticancer peptides from the piscidin family: an expanded mechanism that encompasses physical and chemical bilayer disruption

June 16, 2021

Author(s)

Fatih Comert, Frank N. Heinrich, Ananda Chowdhury, Mason Schoeneck, Caitlin Darling, Kyle Anderson, M. Daben J. Libardo, Alfredo Angeles-Boza, Vitalii I. Silin, Myriam Cotten, Mihaela Mihailescu

In the search for novel broad‑spectrum therapeutics to fight chronic infections, inflammation, and cancer, host defense peptides (HDPs) have garnered increasing interest. Characterizing their biologically‑active conformations and minimum motifs for

ASSESSMENT OF A NOVEL POSITION VERIFICATION SENSOR TO IDENTIFY AND ISOLATE ROBOT WORKCELL HEALTH DEGRADATION

April 1, 2021

Author(s)

Brian A. Weiss, Jared Kaplan

… robot workcell operations to enhance their maintenance strategies. Effective health assessment relies upon capturing …

Evaluating Potential Benefits of Air Barriers in Commercial Buildings using NIST Infiltration Correlations in EnergyPlus

March 15, 2021

Author(s)

Lisa Ng, William Stuart Dols, Steven Emmerich

According to the U. S. Department of Energy (DOE), infiltration accounts for 6 % of the energy use and $11 billion in energy cost for U. S. commercial buildings. One strategy to reduce infiltration in commercial buildings is to provide more supply airflow

Strong Ferromagnetism Achieved via Breathing Lattices in Atomically Thin Cobaltites

January 27, 2021

Author(s)

Sisi Li, Qinghua Zhang, Shan Lin, Xiahan Sang, Ryan F. Need, Manuel A. Roldan, Wenjun Cui, Zhiyi Hu, Qiao Jin, Shuang Chen, Jiali Zhao, Jia-Ou Wang, Jiesu Wang, Meng He, Chen Ge, Can Wang, Hui-Bin Lu, Zhenping Wu, Haizhong Guo, Xin Tong, Tao Zhu, Brian Kirby, Lin Gu, Kui-juan Jin, Er-Jia Guo

Low-dimensional quantum materials that retain strong ferromagnetism down to monolayer thickness hold great potential for spintronic applications. However, ferromagnetism in the transition metal oxides decays severely when the thickness is scaled to the

Ruddlesden-Popper-Phase Hybrid Halide Perovskite/Small-Molecule Organic Blend Memory Transistors

December 31, 2020

Author(s)

Murali Gedda, Emre Yengel, Hendrik Faber, Fabian Paulus, Joshua Kreb, Ming Chun Tang, Siyuan Zhang, Christina A. Hacker, Prashant Kumar, Dipti R. Naphade, Yana Vaynzof, George Volonakis, Feliciano Giustino, Thomas D. Anthopoulos

Controlling the morphology of metal halide perovskite layers during processing is critical for the reliable manufacturing of optoelectronic devices. Here we report on a strategy to control the microstructure of solution-processed layered Ruddlesden-Popper

Realizing Environmentally-Conscious Manufacturing in the Post-COVID-19 Era

December 16, 2020

Author(s)

Nancy Diaz-Elsayed, Julius Schoop, KC Morris

… considered and weighed. In this article, we present strategies for addressing three sustainability challenges …

Error Quantification in Dynamic Applications of Weakly Nonlinear Transducers

November 3, 2020

Author(s)

Lautaro D. Cilenti, Akobuije Chijioke, Balakumar Balachandran

Characterization and quantification of dynamic measurements is an ongoing area of research in the metrological community as new calibration methods are being developed to address dynamic measurement applications. The development undertaken to date largely

Towards model-based integration specifications to secure the extended enterprise

September 30, 2020

Author(s)

Sylvere Krima, Marion Toussaint, Allison Barnard Feeney

With the growing digitalization of manufacturing and the associated reliance on digital data, manufacturers, their supply chains, and their customers are exposed to many and varied digital threats. One such digital threat is compromised integrity of the

Effect of thermal ballast loading on temperature stability of domestic refrigerators used for vaccine storage

July 8, 2020

Author(s)

Michal J. Chojnacky, Alexandra L. Rodriguez

Vaccine temperature control failures represent a significant public and private healthcare cost. Vaccines damaged by excessive heat or freezing lose their effectiveness, putting public health at risk. Some vaccine administration programs recommend placing

Engineering Microporous Ethane-Trapping Metal-Organic Frameworks for Boosting Ethane/Ethylene Separation

February 21, 2020

Author(s)

Jiyan Pei, Jia-Xin Wang, Kai Shao, Yu Yang, Yuanjing Cui, Hui Wu, Wei Zhou, Bin Li, Guodong Qian

Realization of ethane-trapping materials for separating ethane (C 2H 6) from ethylene (C 2H 4) by adsorption, to potentially replace the energy-intensive cryogenic distillation technology, is of prime importance in the petrochemical industry. It is still

Structure of the cell-binding component of the Clostridium difficile binary toxin reveals a di- heptamer macromolecular assembly

January 14, 2020

Author(s)

Xingjian Xu, Raquel Ruiz, Kaylin Adipietro, Christopher Peralta, Danya Ben-Hail, Kristen Varney, Mary Cook, Braden Roth, Paul Wilder, Thomas Cleveland, Alexander Grishaev, Heather Neu, Sarah Michel, Wenbo Yu, Dorothy Beckett, Richard Rustandi, Alex MacKerell, Amedee des Georges, Edwin Pozharski, David Weber

… starting point for developing structure-based drug-design strategies to target the most severe strains of C. difficile. …

Categorization Errors for Data Entry in Maintenance Work-Orders

September 24, 2019

Author(s)

Thurston B. Sexton, Melinda Hodkiewicz, Michael P. Brundage

… (DB) schema. We subsequently suggest potential mitigation strategies for each to improve the quality of recorded data …

Temperature and light intensity effects on the photodegradation of high-density polyethylene

May 11, 2019

Author(s)

Andrew W. Fairbrother, Hsiang C. Hsueh, Jae Hyun Kim, Deborah S. Jacobs, Lakesha N. Perry, David G. Goodwin, Christopher C. White, Stephanie S. Watson, Li Piin Sung

… and can be utilized to develop degradation mitigation strategies for these and related thermoplastic materials. …

A practical field guide to thermoelectrics: fundamentals, synthesis, and characterization

June 27, 2018

Author(s)

Alex Zevalkink, David M. Smiadak, Joshua Martin, Michael Chabinyc, Olivier Delaire, Jeffrey Blackburn, Andrew Ferguson, Jian Wang, Kirill Kovnir, Laura Schelhas, Stephen D. Kang, Maxwell T. Dylla, G. J. Snyder, Brenden Ortiz, Eric Toberer

… inorganic materials, and include a discussion of eﬀective strategies for powder and single crystal synthesis, the use …

PROGRESS AND CHALLENGES IN MODELING COMMUNITY RESILIENCE: AN UPDATE ON THE CENTER FOR RISK-BASED COMMUNITY RESILIENCE PLANNING

June 2, 2018

Author(s)

John W. van de Lindt, Bruce Ellingwood, Therese P. McAllister, Paolo Gardoni, Daniel Cox

… will enable resilience enhancement/planning and recovery strategies to be optimized. The approaches within the CoE …

Nanofiber Scaffold Based Tissue Engineered Retinal Pigment Epithelium to Treat Degenerative Eye Diseases

March 1, 2017

Author(s)

Carl G. Simon Jr., Nathan A. Hotaling

… of one, or a combination, of the tissue engineering strategies discussed herein in a clinical trial. Translation …

Effects of powder recycling on stainless steel powder and built material properties in metal powder bed fusion processes

February 27, 2017

Author(s)

Gregor Jacob, Christopher U. Brown, M A. Donmez, Stephanie S. Watson

A series of 11 identical laser based powder bed fusion (PBF) builds were completed with varying amounts of virgin and recycled nitrogen gas atomized S17-4 PH stainless steel powder following a specific powder recycling strategy that simulates industrial

Tethered Bilayer Membranes as a Complementary Tool for Functional and Structural Studies: the Pyolysin Case

September 1, 2016

Author(s)

Giulio Preta, Marija Jankunec, Frank Heinrich, Sholeem Griffin, Iain Martin Sheldon, Gintaras Valincius

… the activity of CDCs in eukaryotic cells and to develop strategies to limit the toxic effects of CDCs. …

Mixed Ionic/Electronic Conducting Surface Layers Adsorbed on Colloidal Silica for Flow Battery Applications

August 18, 2016

Author(s)

Jeffrey J Richards, Austin D. Scherbarth, Norman J. Wagner, Paul Butler

… is maintained under flow. These results show that strategies which seek to decouple mechanical and electrical …

Real-Time, Single Molecule Electronic DNA Sequencing by Synthesis Using Polymer Tagged Nucleotides on a Nanopore Array

May 10, 2016

Author(s)

Carl Fuller, Shiv Kumar, Mintu Porel, Michen Chien, Arek Bibillo, P. B. Stranges, Michael Dorwart, Chuanjua Tao, Zengmin Li, Wenjing Guo, Shundi Shi, Daniel Korenblum, Andrew Trans, Anne Aguirre, Edward Liu, Takeshi Harada, James Pollard, Ashwini Bhat, Cynthia Cech, Alexander Yang, Cleoma Spilman, Mirko Palla, Jennifer Hovis, Roger Chen, Irina Morozova, Sergey Kalachikov, James Russo, John J. Kasianowicz, Stefan Roever, George Church, Jingyue Ju

DNA sequencing by synthesis (SBS) offers a robust platform to decipher nucleic acid sequences. Recently, we developed a single molecule nanopore-based SBS strategy (NanoSBS) that accurately distinguishes four bases by electronically detecting and

The Importance of Relative Reaction Rates in the Optimization of Detailed Kinetic Models

April 26, 2016

Author(s)

Jeffrey A. Manion, William S. McGivern

Numerous mathematical tools intended to optimize rate constants employed in detailed kinetic models and make them consistent with experimental data have been reported in the literature. A typical methodology begins with the assignment of uncertainties in

Community Resilience Economic Decision Guide for Buildings and Infrastructure Systems An Overview

December 16, 2015

Author(s)

Robert E. Chapman

The Economic Guide provides a standard economic methodology for evaluating investment decisions aimed at improving the ability of communities to adapt to, withstand, and quickly recover from disasters. The Economic Guide is designed for use in conjunction

A Self Learning Algorithm for Temperature Prediction in a Single Family Residence

September 29, 2015

Author(s)

Farhad Omar, Steven T. Bushby

… In order to develop effective control optimization strategies to manage residential electricity consumption in a …

Investigation of lead and cadmium in counterfeit cigarettes seized in the United States

April 8, 2015

Author(s)

Yi He, Klaus von Lampe, Laura J. Wood, Marin Kurti

The information on the content of toxic elements of lead (Pb) and cadmium (Cd) in counterfeit cigarettes offers insight of the potential impact of consuming counterfeit cigarettes on public health and the criminology strategy for investigation of the

Elucidating the Effects of Adsorbent Flexibility on Fluid Adsorption Using Simple Models and Flat-Histogram Sampling Methods

June 24, 2014

Author(s)

Vincent K. Shen, Daniel W. Siderius

Using flat-histogram Monte Carlo methods, we investigate the adsorptive behavior of the square-well fluid in two simple slit-pore- like models intended to capture fundamental characteristics of flexible adsorbent materials. The models require thermodynamic

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