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Displaying 17376 - 17400 of 74253

Structural Changes and Aggregation Mechanisms for Anti-Streptavidin IgG1 at Elevated Concentration

December 10, 2015
Author(s)
Gregory V. Barnett, Wei Qi, Samiul Amin, E. Neil Lewis, Vladimir I. Razinkov, Bruce A. Kerwin, Yun Liu, Christopher J. Roberts
Non-native protein aggregation may occur during manufacturing and storage of protein therapeutics, and this may decrease drug efficacy or jeopardize patient safety. From a regulatory perspective, changes in higher-order structure due to aggregation are of

Trusted Geolocation in the Cloud: Proof of Concept Implementation

December 10, 2015
Author(s)
Michael Bartock, Murugiah Souppaya, Raghuram Yeluri, Uttam Shetty, James Greene, Steve Orrin, Hemma Prafullchandra, John McLeese, Jason Mills, Daniel Carayiannis, Tarik Williams, Karen Scarfone
This publication explains selected security challenges involving Infrastructure as a Service (IaaS) cloud computing technologies and geolocation. It then describes a proof of concept implementation that was designed to address those challenges. The

High-Resolution Imaging and Spectroscopy at High Pressure: A Novel Liquid Cell for the Transmission Electron Microscope

December 9, 2015
Author(s)
Mihaela M. Tanase, Jonathan P. Winterstein, Renu Sharma, Vladimir A. Aksyuk, Glenn E. Holland, James A. Liddle
We demonstrate quantitative core-loss electron energy-loss spectroscopy of iron oxide nanoparticles and imaging resolution of Ag nanoparticles in liquid down to 0.24 nm, in both transmission and scanning-transmission modes, in a novel, monolithic liquid

Magnetic Fluctuations Driven Insulator-to-Metal Transition in Ca(Ir 1-x Ru x )O 3

December 9, 2015
Author(s)
J. Gunasekera, Leland Harriger, A. Dahal, T. Heitmann, G. Vignale, D. K. Singh
Magnetic fluctuations in transition metal oxides are a subject of intensive research because of the key role they are expected to play in the transition from the Mott insulator to the unconventional metallic phase of these materials, and also as drivers of

Phase Separation Enhanced Magneto-Electric Coupling in La 0.7 Ca 0.3 MnO 3 /BaTiO 3 Ultra-thin Films

December 9, 2015
Author(s)
A. Alberca, C. Munuera, Brian Kirby, N. M. Nemes, A. M. Perez-Munoz, J. Tornos, F. J. Mompean, C. Leon, J. Santamaria, M. Garcia-Hernandez
We study the origin of the magnetoelectric coupling in manganite films on ferroelectric substrates. We find large magnetoelectric coupling in La 0.7Ca 0.3MnO 3/BaTiO 3 ultra-thin films in experiments based on the converse magnetoelectric effect. The

Quantifying "Softness" of Organic Coatings on Gold Nanoparticles using Correlated Small-Angle X-Ray and Neutron Scattering

December 9, 2015
Author(s)
Benjamin T. Diroll, Kathleen Weigandt, Davit Jishkariani, Matteo Cargnello, Ryan J. Murphy, Lawrence A. Hough, Christopher B. Murray, Bertrand Donnio
Small angle X-ray and neutron scattering provide powerful tools to selectively characterize the inorganic and organic components of hybrid nanomaterials. Using hydrophobic gold nanoparticles coated with several commercial and dendritic thiols, the size of

Urinary iodine and stable isotope analysis to examine habitat influences on thyroid hormones among coastal dwelling American alligators

December 9, 2015
Author(s)
Ashley S. Boggs-Russell, Heather J. Hamlin, James C. Nifong, Brittany L. Kassim, Russell H. Lowers, Thomas M. Galligan, Stephen E. Long, Louis J. Guillette Jr.
The American alligator, a freshwater species, is known to forage in marine environments which could lead to increased dietary uptake of iodine, a nutrient necessary for the production of thyroid hormones. To explore the influence of dietary iodine on

Developments in time-division multiplexing of X-ray transition-edge sensors.

December 8, 2015
Author(s)
William B. Doriese, Kelsey M. Morgan, Douglas A. Bennett, Edward V. Denison, Colin P. Fitzgerald, Joseph W. Fowler, Johnathon D. Gard, James P. Hays-Wehle, Gene C. Hilton, Kent D. Irwin, Young Il Joe, John A. Mates, Galen C. O'Neil, Carl D. Reintsema, Nigel O. Robbins, Daniel R. Schmidt, Daniel S. Swetz, Hideyuki Tatsuno, Joel N. Ullom, Leila R. Vale
Time-division multiplexing (TDM) is a mature scheme for the readout of transition-edge sensors. Variants of TDM, which is based on superconducting-quantum-interference-device (SQUID) current amplifiers, have to date been field-deployed in several

Heat pump concepts for nZEB Technology developments, design tools and testing of heat pump systems for nZEB in the USA, Country report IEA HPT Annex 40 Task 2, Task 3 and Task 4 of the USA

December 8, 2015
Author(s)
William V. Payne, Arthur H. Fanney, William M. Healy, Joshua D. Kneifel, Tania Ullah, Farhad Omar, Steven T. Bushby, Brian P. Dougherty, Dustin G. Poppendieck, Lisa C. Ng
The IEA HPT Annex 40 "Heat pump concepts for Nearly Zero Energy Buildings" deals with the application of heat pumps as a core component of the HVAC system for Nearly or Net Zero energy buildings (NZEB). This report covers Task 2 on the system comparison

Integrity of Bolted Angle Connections Subjected to Simulated Column Removal

December 8, 2015
Author(s)
Jonathan M. Weigand, Jeffrey W. Berman
Large-scale tests of steel gravity framing systems (SGFSs), one of the most commonly used structural systems in the United States, have shown that enhancements may be required to achieve the desired levels of integrity to collapse when a column suffers

One Dimensional(1D)-to-2D Crossover of Spin Correlations in the 3D Magnet ZnMn 2 O 4

December 8, 2015
Author(s)
Steven M.T. Disseler, Ying Chen, S. Yeo, G. Gasparovic, P.M.B. Piccoli, A. J. Schultz, Yiming Qiu, Qingzhen Huang, S.-W. Cheong, William D. Ratcliff
We report on the intriguing evolution of the dynamical spin correlations of the frustrated spinel ZnMn 2O 4. Inelastic neutron scattering and magnetization studies reveal that the dynamical correlations at high temperatures are 1D. At lower temperature
Displaying 17376 - 17400 of 74253
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