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Displaying 1 - 25 of 53805

Inhibition by Tetrahydroquinoline Sulfonamide Derivatives of the Activity of Human 8-Oxoguanine DNA Glycosylase (OGG1) for Several Products of Oxidatively-induced DNA Base Lesions

December 17, 2021
Author(s)
Miral M. Dizdar, Melis Kant, Pawel Jaruga, Erdem Coskun, Yu-Ki Tahara, R. S. Lloyd, Eric T. Kool
DNA glycosylases involved in the first step of the base excision repair pathway of DNA repair are promising targets in cancer therapy. There is evidence that reduction of their activities may enhance cell killing in malignant tumors. Recently, two

Inert Gas Flow Speed Measurements in Laser Powder Bed Fusion Additive Manufacturing

October 19, 2021
Author(s)
Jordan Weaver, Alec Schlenoff, David Deisenroth, Shawn P. Moylan
Laser powder bed fusion (LPBF) is an additive manufacturing technology that uses a laser to selectively melt powder feedstock to build parts in a layer-by-layer process. For metals-based LBPF additive manufacturing, the interaction of the laser and powder

Modeling Public Safety Communication Scenarios: School Shooting Incident

October 15, 2021
Author(s)
Richard A. Rouil, Antonio Izquierdo Manzanares, Chunmei Liu, Wesley Garey
Public safety practitioners performing day-to-day activities and responding to incidents communicate in ways that are very different from the general public. In order to determine if a particular technology or network deployment can meet the performance

Low-GWP Alternative Refrigerant Blends for HFC-134a: Interim Report

October 13, 2021
Author(s)
Piotr A. Domanski, Mark O. McLinden, Valeri I. Babushok, Ian Bell, Tara Fortin, Michael Hegetschweiler, Mark A. Kedzierski, Dennis Kim, Lingnan Lin, Gregory T. Linteris, Stephanie L. Outcalt, Richard A. Perkins, Aaron Rowane, Harrison Skye
This project addresses the objectives of the Statement of Need number WPSON-17-20 "No/Low Global Warming Potential Alternatives to Ozone Depleting Refrigerants." Its goal is to identify and demonstrate performance of low global-warming-potential (GWP), non

STEP File Analyzer and Viewer User Guide (Update 7)

October 13, 2021
Author(s)
Robert R. Lipman
The STEP File Analyzer and Viewer opens a STEP (ISO 10303 - STandard for Exchange of Product model data) Part 21 file and (1) generates a spreadsheet or CSV files of all entity and attribute information, (2) creates a visualization (view) of part geometry

Thermal Analysis of Nanoparticles: Methods, Kinetics, and Recent Advances

October 13, 2021
Author(s)
Elisabeth Mansfield, Mark Banash
This chapter provides an overview of the thermal techniques available to study nanoparticles, with particular attention to thermogravimetric analysis, calorimetry and differential scanning calorimetry. The advantages of thermal analysis for nanoparticle

A Combinatorial Approach to TCO Synthesis and Characterization

October 12, 2021
Author(s)
J D. Perkins, Dennis W. Readey, J. L. Alleman, J A. del Cueto, King C. Li, T J. Coutts, R Stauber, C. H. Duncan, David P. Young, P A. Parilla, B Keyes, L M. Geduilas, Davor Balzar, Q Wang, D Ginley
We have developed the deposition, characterization and analysis tools necessary for a combinatorial approach to thin flim metal oxides, with a special focus on transparent conducting oxides (TCOs). We are presently depositing compositionally graded

A Comparative AFM Study of the Compressibility and Friction of Unmodified and Oligo(ethylene oxide)-Modified Alkane Thiol SAMs on Au(111) Using Nanografting

October 12, 2021
Author(s)
Ying Hu, David J. Vanderah, Guangyao Liu, William J. Price, Milan Mrksich, G Scoles
Self-assembled monolayers (SAMs) terminated with oligo(ethylene glycol) (OEG) segments are known to resist non-specific protein adsorption and are used in biomaterial and biosensor applications. In this report we use an atomic force microscopy (AFM)

A Continuum-Atomistic Simulation of Heat Transfer in Micro- and Nano-Flows

October 12, 2021
Author(s)
J Liu, S Chen, Xiaobo Nie, M O. Robbins
We develop a hybrid atomistic-continuum scheme for simulating micro- and nano- flows with heat transfer. The approach is based on spatial ''domain decomposition'' in which molecular dynamics (MD) is used in regions where atomistic details are important

A Field Unit for Spectral Irradiance Responsivity Calibrations

October 12, 2021
Author(s)
E A. Thompson, P Disterhoft, E A. Early
Withdrawn by author - 11/10/97Horizontal standard lamps calibrate the spectral irradiance responsivity of spectroradiometers which measures solar ultraviolet irradiance. Experience at field instrument intercomparisons suggested several important

A High-Field, Low-Current Superconducting Ioffe Magnetic Trap

October 12, 2021
Author(s)
S N. Dzhosyuk, C R. Brome, J S. Butterworth, P R. Huffman, C E. Mattoni, D N. McKinsey, R A. Michniak, L Yang, John M. Doyle
A superconducting Ioffe magnetic trap is designed, built and characterized. The trap consists of four racetrack-shaped quadrupole coils and two solenoid assemblies. Coils are wet wound with multifilament copper-clad NgTi superconducting wire embedded in an

A Loop in the N-terminal Region of MCM Mediates Communication With the Catalytic Domain

October 12, 2021
Author(s)
Nozomi Sakakibara, Rajesh Kasiviswanathan, E Melamud, Frederick P. Schwarz, Z Kelman
Minichromosome maintenance helicases are the presumptive replicative helicases, thought to separate the two strands of chromosomal DNA during replication. In archaea, the catalytic activity resides within the C-terminal region of the MCM protein. In

A Minimalist Sensor System for Mold Filling

October 12, 2021
Author(s)
S R. Kueh, S G. Advani, Richard~undefined~undefined~undefined~undefined~undefined Parnas
Reliable mold filling remains the most critical issue in the commercial application of liquid composite molding. Many techniques of observing the flow are either cumbersome or too invasive for routine service. Combining the sensor output from a single
Displaying 1 - 25 of 53805