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Certification of Standard Reference Material® 3383: Yohimbe-Containing Solid Oral Dosage Form



Walter Brent Wilson, Sanem Hosbas Coskun, Jerome Mulloor, Michael Nelson, James H. Yen


Standard Reference Material® (SRM®) 3383 Yohimbe-Containing Solid Oral Dosage Form was developed as part of a collaborative effort between the National Institute for Standards and Technology (NIST) and the National Institutes of Health Office of Dietary Supplements (NIH-ODS). SRM 3383 was produced from multiple commercial dietary supplements containing yohimbe to replicate typical analytical challenges associated with the measurement of yohimbine in a finished product sample matrix. The material was prepared at NIST and packaged by High Purity Standards, an experienced contract manufacturer. A certified value for yohimbine has been assigned based upon data obtained from NIST. A description of the material, sample preparations, results, and data analysis are discussed in the following report.
Special Publication (NIST SP) - 260-240
Report Number


Dietary Supplement, Rauhimbine, Solid Oral Dosage Form, Yohimbe, Yohimbine.


Wilson, W. , Hosbas Coskun, S. , Mulloor, J. , Nelson, M. and Yen, J. (2024), Certification of Standard Reference Material® 3383: Yohimbe-Containing Solid Oral Dosage Form, Special Publication (NIST SP), National Institute of Standards and Technology, Gaithersburg, MD, [online],, (Accessed May 19, 2024)


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Created April 22, 2024