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Performing Skin Microbiome Research: A Method to the Madness
Published
Author(s)
Heidi H. Kong, Bjorn Andersson, Thomas Clavel, John E. Common, Scott Jackson, Nathanael Olson, Julia Segre, Claudia Traidl-Hoffman
Abstract
Growing interest in microbial contributions to human health and disease has increasingly led investigators to examine the microbiome in both healthy skin and cutaneous disorders, including acne, psoriasis, and atopic dermatitis. The need for common language, effective study design, and validated methods is critical for high-quality standardized research. Features, unique to skin, pose particular challenges when conducting microbiome research. This review discusses microbiome research standards and highlights important factors to consider, including clinical study design, skin sampling, sample processing, DNA sequencing, control inclusion, and data analysis.
Kong, H.
, Andersson, B.
, Clavel, T.
, Common, J.
, Jackson, S.
, Olson, N.
, Segre, J.
and Traidl-Hoffman, C.
(2017),
Performing Skin Microbiome Research: A Method to the Madness, Journal of Investigative Dermatology, [online], https://doi.org/10.1016/j.jid.2016.10.033
(Accessed October 11, 2025)