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Performing Skin Microbiome Research: A Method to the Madness



Heidi H. Kong, Bj?rn Andersson, Thomas Clavel, John E. Common, Scott Jackson, Nathanael David Olson, Julia Segre, Claudia Traidl-Hoffman


Growing interest in microbial contributions to human health and disease has increasingly led investigators to examine the microbiome in both healthy skin and cutaneous disorders, including acne, psoriasis, and atopic dermatitis. The need for common language, effective study design, and validated methods is critical for high-quality standardized research. Features, unique to skin, pose particular challenges when conducting microbiome research. This review discusses microbiome research standards and highlights important factors to consider, including clinical study design, skin sampling, sample processing, DNA sequencing, control inclusion, and data analysis.
Journal of Investigative Dermatology


Kong, H. , Andersson, B. , Clavel, T. , Common, J. , Jackson, S. , Olson, N. , Segre, J. and Traidl-Hoffman, C. (2027), Performing Skin Microbiome Research: A Method to the Madness, Journal of Investigative Dermatology, [online], (Accessed February 24, 2024)
Created March 1, 2027, Updated January 31, 2024