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Haden L. Scott, Allison Skinkle, Elizabeth Kelley, M. Neal Waxham, Ilya Levental, Frederick A. Heberle
Extrusion through porous filters is the most widely used method for preparing biomimetic model membranes. Of primary importance in this approach is the efficient production of single bilayer (unilamellar) vesicles that eliminate the influence of
Dusan Sarenac, Connor Kapahi, Wangchun Chen, Charles W. Clark, David G. Cory, Michael G. Huber, Ivar Taminiau, Kirill Zhernenkov, Dmitry A. Pushin
Spin-orbit coupling of light has come to the fore in nano-optics and plasmonics, and is a key ingredient of topological photonics and chiral quantum optics. We demonstrate a basic tool for incorporating analogous effects into neutron optics: the generation
Amy Yuanyuan Xu, Maria Monica Castellanos, Kevin Mattison, Joseph Curtis
Excipients are a class of pharmacologically inert chemicals that are frequently added into concentrated therapeutic protein formulations for improved protein stability and reduced solutions viscosity. In concentrated protein formulations ,undesirable
Mitchell M. Bordelon, Eric Kenney, Chunxiao Liu, Tom Hogan, Lorenzo Posthuma, Marzieh Kavand, Yuangqi Lyu, Mark Sherwin, Nicholas Butch, Craig Brown, M. J. Graf, Leon Balents, Stephen D. Wilson
One of the simplest routes to pursuing magnets with strong quantum fluctuations that quench conventional order is via decorating a triangular lattice with antiferromagnetically coupled S=1/2 moments. As disorder and anisotropies inherent in materials
Yuexi Chen, Cheol Jeong, Alexey Savelyev, Susan T. Krueger, Joseph E. Curtis, Emre H. Brookes, David Fushman
Proteins and nucleic acids participate in essentially every biochemical process in living organisms, and the elucidation of their structure and motions is essential for our understanding how these molecular machines perform their function. Nuclear Magnetic
Jia-Yu Wang, Wei Chen, Michihiro Nagao, Phullara Shelat, Brenton A. G. Hammer, Gregory T. Tietjen, Kathleen Cao, J. Michael Henderson, Lilin He, Binhua Lin, Bulent Akgun, Mati Meron, Shuo Qian, Sarah Ward, Jeremy D. Marks, Todd Emrick, Ka Yee C. Lee
Some synthetic polymers have been found capable of rescuing injured cells from death by targeting cell membranes. However, general principles for designing synthetic polymers to ensure strong, but non-disruptive cell membrane targeting unknown. Here, we
Jeffrey Jones, Vinh Ta Phuoc, Leire del Campo, Nestor E. Massa, Craig Brown, Silvina Pagola
Two polymorphs of tetrathiafulvalene chloranilic acid (ITF-CAH 2) have been synthesized by mechanochemistry. The previously known "ionic" polymorph (form I), was prepared by liquid assisted grinding (LAG) using various highly polar solvents; as well as
Kanokporn Chattrakun, David Hoogerheide, Chunfeng Mao, Linda L. Randall, Gavin M. King
Surface-supported lipid bilayers are used widely throughout the nanoscience community as robust mimics of cellular membrane. For example, they are frequently employed in single molecule atomic force microscopy (AFM) studies to shed light on membrane
Daria Noferini, Antonio Faraone, Marta Rossi, Eugene Mamontov, Emiliano Fratini, Piero Baglioni
Cross-linker nature and water content may impact the microscopic dynamics of hydrogels components, and thus their properties in applications such as drug-delivery. To investigate this aspect, we used quasi-elastic neutron scattering with contrast variation
Alexander V. Skripov, Mirjana NMN Dimitrievska, Olga A. Babanova, R. V. Skoryunov, Alexei V. Soloninin, Fabrice Morelle, Y. Filinchuk, Antonio Faraone, Hui Wu, Wei Zhou, Terrence J. Udovic
To investigate the dynamical properties of the novel hybrid compound, lithium benzimidazolate-borohydride Li 2(bIm)BH 4 (where bIm denotes a benzimidazolate anion, C 7N 2H 5u-^), we have used a set of complementary techniques: neutron powder diffraction
Samuel Bowerman, Joseph E. Curtis, Joseph Clayton, Emre H. Brookes, Jeff Wereszczynski
Many biomolecular complexes exhibit a flexible ensemble of conformations in solution in order to conduct their biological function. Small angle scattering (SAS) measurements are a popular method for characterizing these flexible molecules due to their