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Standards

Reference materials

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Displaying 476 - 500 of 1013

Establishing Traceability to NIST SRM 2391c: PCR-Based DNA Profiling Standard

September 16, 2015
Author(s)
Carolyn R. Steffen, Margaret C. Kline, David L. Duewer, Peter Vallone
The NIST Standard Reference Material (SRM) 2391c: PCR-Based DNA Profiling Standard was updated in April 2015 to contain new information relevant to the forensic community. Previously, there were certified genotypes for 24 autosomal STR markers plus

Development of an Ultra-Pure, Carrier-Free 209Po Solution Standard

July 23, 2015
Author(s)
Ronald Colle, Ryan P. Fitzgerald, Lizbeth Laureano-Perez
Ultra-pure, carrier-free 209Po solution standards have been prepared and standardized for their massic alpha-particle emission rate. The standards, which will be disseminated by the National Institute of Standards and Technology (NIST) as Standard

Quantifying and Improving Clinical-grade Coverage and Accuracy using Augmented Exome Sequencing

July 16, 2015
Author(s)
Justin M. Zook, Anil Patwardhan, Marc L. Salit, Carlos Bustamante, Euan Ashley, Michael Snyder, John West, Richard Chen
Exome sequencing is increasingly used for the clinical evaluation of genetic disease, yet accuracy and coverage in medically interpretable parts of the genome remains under-characterized. We evaluate recently developed exome sequencing platforms in the

MEMS optomechanical accelerometry standards

July 8, 2015
Author(s)
Felipe Guzman, Yiliang Bao, Jason J. Gorman, John R. Lawall, Jacob M. Taylor, Thomas W. LeBrun
Current acceleration primary standards reach relative uncertainties of the order of 0.001 and consist of complex test facilities, typically operated at National Metrology Institutes. Our research focuses on the development of silicon mechanical oscillator

Optomechanical Motion Sensors

July 8, 2015
Author(s)
Felipe Guzman, Oliver Gerberding, John T. Melcher, Julian Stirling, Jon R. Pratt, Gordon A. Shaw, Jacob M. Taylor
Compact optical cavities can be combined with motion sensors to yield unprecedented resolution and SI-traceability in areas such as acceleration sensing and atomic force microscopy AFM, among others. We have incorporated Fabry-Perot fiber-optic micro

Best Practices for Evaluating Single Nucleotide Variant Calling Methods for Microbial Genomics

July 7, 2015
Author(s)
Nathanael D. Olson, Steven P. Lund, Rebecca Colman, Jeffery T. Foster, Jason W. Sahl, James M. Schupp, Paul Keim, Jayne B. Morrow, Marc L. Salit, Justin M. Zook
Innovations in sequencing technologies have allowed biologists to make incredible advances in understanding biological systems. As experience grows, researchers increasingly recognize that analyzing the wealth of data provided by these new sequencing

Design and Capabilities of NISTs Scale-Model Smokestack Simulator (SMSS)

April 17, 2015
Author(s)
Aaron N. Johnson, Joey T. Boyd, Eric Harman, Mohammad M. Khalil, Jacob E. Ricker, Christopher J. Crowley, Rodney A. Bryant, Iosif I. Shinder
The amount of CO 2 emitted from a coal-fired power plant (CFPP) is measured by continuous emissions monitoring systems (CEMS) permanently installed in the exhaust smokestack. Both the CO 2 concentration and the bulk flow are continuously measured by CEMS