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Rigorous validation of biomarkers at the National Institute of Standards and Technology (NIST) for early detection of cancer differs from similar processes common among research laboratories. As a newly discovered biomarker assay makes the transition from
Barbara C. Levin, L A. Tully, Diane K. Hancock, Frederick P. Schwarz, M S. Lee
Every human cell has from a few dozen to several thousand mitochondria each of which contain mitochondrial DNA (mtDNA). The sequence of the entire human mtDNA (16,569 base pairs) was determined and published by Anderson et al. in 1981. A mtDNA standard
The measurement of particle size distributions has become increasingly important for the testing and certification of equipment used in size analysis. Requirements for quality control compliance with the ISO 9000 series of quality standards have emphasized
Peter E. Barker, M S. Watson, J R. Ticehurst, Jennifer C. Colbert, C D. O'Connell
As DNA and RNA become major targets for clinical laboratory analysis, benchmark reagents will play an increasingly important role in standardization. Reliable national and international nucleic acid standards promote automation, third party reimbursement
To address a fundamental need in stable isotope metrology, the National Institute of Standards and Technology (NIST) has established a Web-based interactive data processing system accessible through a common gateway interface (CGI) program on the internet
To eliminate measurement-base trade barriers to international commerce, Key Comparisons (KCS) are now being planned in the newly formed Working Group for Fluid Flow (WGFF) in the CIPM to quantify the equivalency of the flow standards maintained in the
R. H. Christenson, S. H. Duh, F. S. Apple, G. S. Bodor, David M. Bunk, J. J. Dalluge, Mauro Panteghini, J. D. Potter, Michael J. Welch, A. H. Wu, S. E. Kahn