U.S. flag

An official website of the United States government

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

Forensic science

Forensic genetics

Search Publications

Search Title, Abstract, Conference, Citation, Keyword or Author
Published Date
Displaying 1 - 25 of 257

INTERPOL Review of Forensic Biology and DNA, 2023-2025

June 14, 2026
Author(s)
John Butler
As a part of the 21st INTERPOL International Forensic Science Managers Symposium, this work explores the latest scientific developments, methodologies, and trends in forensic biology and forensic DNA analysis of biological evidence during the years 2023 to

Developmental Validation of the PowerPlex(R) 18E System: An 8-Dye STR Multiplex for Human Identification Applications

April 28, 2026
Author(s)
Jonelle Thompson, Michael Lauck, Elizabeth Hamilton, Heather Hodges, Maximilian Neis, Cornelius Courts, Aimee Hack, Alan Pierce, David Moore, Katja Anslinger, Birgit Bayer, Peter Vallone, Carolyn Steffen, Rachel Knoener, Karthika Karthika Divakaran, Stephen McDaniel, Robert McLaren
The PowerPlex® 18E System is an 18-locus, eight-dye, STR multiplex optimized for use with the Spectrum CE System and Spectrum Compact CE System. It simultaneously amplifies all 16 ENFSI-recommended loci and two gender-determining loci. In addition, there

Development of Publicly Available Forensic DNA Sequence Mixture Data

March 12, 2025
Author(s)
Erica Romsos, Kevin Kiesler, Carolyn Steffen, Lisa Borsuk, Sarah Riman, Lauren Mullen, Jodi Irwin, Peter Vallone, Katherine Gettings
Background: In 2018, the Next-Generation Sequencing Committee of SWGDAM queried bioinformatic and statistical interpretation method developers regarding data needs for the development of sequence-based probabilistic genotyping software. Methods: Based on

DNA Mixture Interpretation: A NIST Scientific Foundation Review

December 18, 2024
Author(s)
John Butler, Hariharan Iyer, Richard Press, Melissa Taylor, Peter Vallone, Sheila Willis
Improvements in DNA testing methods have allowed forensic scientists to reduce the quantity of DNA required for profiling an individual. Today, DNA profiles can be generated from a few skin cells. This increased sensitivity has extended the usefulness of

Results of the 2023 Rapid DNA Multi-Laboratory Study - I-Chip

December 4, 2024
Author(s)
Erica Romsos, Lilliana Moreno, Douglas Hares
Identical sensitivity and mixture sample sets were provided to six external laboratories to evaluate the recent enhancements to the Rapid DNA technology for crime scene-type samples. Data were returned to the Federal Bureau of Investigation and the

Development of a Forensic DNA Research Grade Test Material

October 16, 2024
Author(s)
Erica Romsos, Lisa Borsuk, Carolyn Steffen, Sarah Riman, Kevin Kiesler, Peter Vallone
Advancements in forensic DNA typing technology and methods have resulted in increased sensitivity and, while beneficial, carry the weight of more challenging profile interpretation. In response, the forensic DNA community has often requested more complex

Review of SNP assays for DVI: cost, time, and performance information for decision-makers

July 17, 2024
Author(s)
Katherine Gettings, Andreas Tillmar, Kimberly Sturk-Andreaggi, Charla Marshall
In mass disaster events, forensic DNA laboratories may be called upon to quickly pivot their operations toward identifying bodies and reuniting remains with family members. Ideally, laboratories have considered this possibility in advance and have a plan

Harmonizing the forensic nomenclature for STR Loci D6S474 and DYS612

January 21, 2024
Author(s)
Martin Bodner, David Ballard, Lisa Borsuk, Jonathan King, Walther Parson, Christopher Phillips, Katherine Gettings
The autosomal short tandem repeat (STR) locus D6S474 and the Y-chromosomal STR locus DYS612 have been reported multiple ways in the forensic literature, with differences in both the bracketed repeat structures and counting of numerical length-based

STRSeq: FAQ for submitting

December 1, 2022
Author(s)
Lisa Borsuk, Peter Vallone, Katherine Gettings
The STR sequencing project was developed due to the necessity of publicly sharing sequencing information about Short Tandem Repeats (STR) associated with human identification. Next Generation Sequencing (NGS) or Massively Parallel Sequencing (MPS) is

Sequence-based U.S. population data for 7 X STR loci

April 26, 2021
Author(s)
Lisa Borsuk, Carolyn R. Steffen, Kevin M. Kiesler, Peter Vallone, Katherine Gettings
The National Institute of Standards and Technology (NIST) U.S. population sample set of unrelated individuals was used to determine allele and haplotype frequencies for seven X-chromosome short tandem repeat (STR) loci in four linkage groups. DXS7132
Was this page helpful?