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Bioscience

Proteomics

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Displaying 76 - 100 of 131

Mass spectrometry enumeration of filamentous M13 bacteriophage

July 2, 2019
Author(s)
Tingting Wang, Ai Nguyen, Linwen Zhang, Illarion Turko
In the last decade, filamentous M13 bacteriophage has emerged into numerous biotechnological applications as a promising nontoxic and self-assembling biomaterial with specific binding properties. This raises a question about its upscale production that

Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS) Centroid Data Measured between 3.6 degC and 25.4 degC for the Fab Fragment of NISTmAb

May 2, 2019
Author(s)
Jeffrey W. Hudgens, Elyssia S. Gallagher, Ioannis L. Karageorgos, Kyle W. Anderson, Richard Y. Huang, Guodong Chen, George M. Bou-Assaf, Alfonso Espada, Michael J. Chalmers, Edu Harguindey, Hui-Min Zhang, Benjamin T. Walters, Jennifer Zhang, John Venable, Caitlin Steckler, In Hee Park, Ansgar Brock, Xiaojun Lu, Ratnesh Pandey, Arun Chandramohan, Ganesh Srinivasan Anand, Sasidhar N. Nirudodhi, Justin Sperry, Jason C. Rouse, James A. Carroll, Kasper D. Rand, Ulrike Leurs, David D. Weis, Mohammed A. Al-Naqshabandi, Daniel Deredge, Patrick Wintrode, Malvina Papanastasiou, John D. Lambris, Sheng Li, Sarah Urata
The spreadsheet file reported herein provides centroid data, descriptive of deuterium uptake, for the Fab Fragment of NISTmAb (PDB: 5K8A) reference material, as measured by the bottom-up hydrogen-deuterium exchange mass spectrometry (HDX-MS) method. The

Targeting hMSC Response via Surface Carbonyl Groups, Contact Angle, and Protein Interactions

March 1, 2019
Author(s)
Max J. Lerman, Shinichiro Muramoto, Navein Arumugasaamy, Michael Van Order, Josephine Lembong, Anushka Gerald, John G. Gillen, John P. Fisher
Traditional 2D culture systems made of polystyrene (PS) require the addition of surface chemistry beyond the nominal phenyl groups present to facilitate and encourage cell adhesion. Determining the surface properties which enhance protein adhesion from

Progress and Challenges in Ocean Metaproteomics and Proposed Best Practices for Data Sharing

January 31, 2019
Author(s)
Mak Saito, Erin Bertrand, Megan Duffy, David Gaylord, Noelle Held, Judson Harvey, Robert Hettich, Pratik Jagtap, Michael G. Janech, Danie Kinkade, Dasha Leary, Matt McIlvin, Eli Moore, Robert Morris, Ben Neely, Brook Nunn, Jaclyn Sanders, Adam Shepherd, Nick Symmonds, David Walsh
Ocean metaproteomics is an emerging field that provides an exciting new datatype with potential to enable discoveries regarding marine microbial communities and their underlying impact on global biogeochemical processes. For example, recent ocean

The integration of emerging omics approaches to advance precision medicine: How can regulatory science help?

December 6, 2018
Author(s)
Mark S. Lowenthal, Christina M. Jones, Joan Adamo, Robert Bienvenu, Owen Fields, Soma Ghosh, Michael Liebman, Robert Schuck, Scott Steele
Building on the recent advances in next-generation sequencing, the integration of genomics, proteomics, metabolomics, and other approaches hold tremendous promise for precision medicine. The approval and adoption of these rapidly advancing technologies and

Harmonization of LC-MS/MS protein assays

September 24, 2018
Author(s)
Alan L. Rockwood, Mark Lowenthal, Cory Bystrom
Harmonization of diagnostic test results is fundamental to the effective use of laboratory testing in the diagnosis, treatment and monitoring of disease. Formal approaches to harmonization and standardization provide a rigorous and high quality Roadmap to
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