Davis, W.
, Kilpatrick, L.
, Ellisor, D.
and Neely, B.
(2019),
Characterization of a Human Liver NIST Reference Material fit for Proteomics Applications, Scientific Data, [online], https://doi.org/10.1038/s41597-019-0336-7, https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=928171
(Accessed July 9, 2025)
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Characterization of a Human Liver NIST Reference Material fit for Proteomics Applications
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Abstract
The National Institute of Standards and Technology (NIST) is creating new, inexpensive, qualitative reference materials and data for proteomics comparisons, benchmarking and harmonization. Here we describe a large dataset from shotgun proteomic analysis of RM 8461 Human Liver for Proteomics. Consensus identifications using multiple search engines and sample preparations demonstrate a homogeneous and fit-for-purpose material that can be incorporated into automated or manual sample preparation workflows, with the resulting data used to directly assess complete sample-to-data workflows and provide harmonization and benchmarking between laboratories and techniques. Data are available via PRIDE with identifier PXD013608Citation
Scientific Data
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Keywords
Reference Materials, Proteomics, LC/MS/MS
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Created December 17, 2019, Updated October 13, 2022