Proteomics

News and Updates

Petri dish holds brown material with several different types of circular microbes.

Spotlight: Going With the Gut for the Future of Health

June 27, 2022

NIST researchers are developing a human gut microbiome reference material.

Woman uses gas analysis mass spectrometer at NBS for chemical analysis of gas or vapor mixtures

NIST Adds New 'Fingerprints' to Chemical Identification Database

June 17, 2020

The National Institute of Standards and Technology (NIST) has updated its database of chemical fingerprints, called mass spectra, that are used to identify

A Solution to a Hairy Problem in Forensic Science

November 5, 2019

In an effort to make hair comparison a more useful technique for investigating crimes, scientists at the National Institute of Standards and Technology (NIST)

Projects and Programs

Trusted AI framework for a new class of Standard Reference Materials and Data with exquisitely characterized uncertainty for billions of properties

Ongoing

A new collaboration between NIST's Human Genomics Team , Mass Spectrometry Data Center , and Information Technology Laboratory to use and develop artificial

Monoclonal Antibody Mass Spectral Libraries

Ongoing

The National Institute of Standards and Technology is developing a mass spectral library of all identifiable components derived from the digestion of monoclonal

Comparative Mammalian Proteome Aggregator Resource (CoMPARe) Program

Ongoing

NIST is developing a portal to enable researchers to mine high-quality proteomic data from phylogenetically diverse species, to identify advantageous biological

Development of NIST Reference Materials for Untargeted Metabolomics, Lipidomics and Proteomics

Ongoing

The use of metabolite, lipid, and protein profiles for systems biology, biomedical research, and clinical applications has risen dramatically over recent years

Publications

Proteomics as a metrological tool to evaluate genome annotation accuracy following de novo genome assembly: a case study using the Atlantic bottlenose dolphin (Tursiops truncatus)

August 25, 2023

Author(s)

Ben Neely, Debra Ellisor, Clay Davis

The last decade has witnessed dramatic improvements in whole-genome sequencing capabilities coupled to drastically decreased costs, leading to an inundation of

The Association of Biomolecular Resource Facilities Proteome Informatics Research Group Study on Metaproteomics (iPRG-2020)

August 7, 2023

Author(s)

Pratik Jagtap, Michael Hoopmann, Ben Neely, Anthony Harvey, Lukas Käll, Yasset Perez-Riverol, Milky Abajorga, Julie Thomas, Susan Weintraub, Magnus Palmblad

Metaproteomics research using mass spectrometry data has emerged as a powerful strategy to understand the mechanisms underlying microbiome dynamics and the

Certification of Standard Reference Material® 3666 Albumin and Creatinine in Frozen Human Urine

June 26, 2023

Author(s)

Ashley Beasley Green, Johanna Camara, N. Alan Heckert

The National Institute of Standards and Technology (NIST) Standard Reference Material® (SRM®) 3666 Albumin and Creatinine in Frozen Human Urine (Level 1 to

2019 Association of Biomolecular Resource Facilities Multi-laboratory Data-Independent Acquisition Study

June 2, 2023

Author(s)

Ben Neely, Paul Stemmer, Brian Searle, Laura Herring, LeRoy Martin, Mukul Midha, Brett Phinney, Baozhen Shan, Magnus Palmblad, Yan Wang, Pratik Jagtap, Joanna Kirkpatrick

Despite the advantages of fewer missing values by collecting fragment ion data on all analytes in the sample as well as the potential for deeper coverage, the

Awards

John Marino Honored with Hillebrand Prize

John Marino is recognized for his groundbreaking contributions to the field of biophysical characterization by high-resolution NMR and