Rockwood, A.
, Lowenthal, M.
and Bystrom, C.
(2018),
Harmonization of LC-MS/MS protein assays, Clinics in Laboratory Medicine, [online], https://doi.org/10.1016/j.cll.2018.05.004, https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=925783
(Accessed October 7, 2024)
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Harmonization of LC-MS/MS protein assays
Published
Author(s)
Alan L. Rockwood, , Cory Bystrom
Abstract
Harmonization of diagnostic test results is fundamental to the effective use of laboratory testing in the diagnosis, treatment and monitoring of disease. Formal approaches to harmonization and standardization provide a rigorous and high quality Roadmap to this end, though the formal harmonization process can be long and complex. In the meantime, more informal approaches to harmonization can provide a useful pathway to improved harmonization in the short term. Factors relevant to harmonization are discussed with particular attention to protein assays employing LC- MS/MS. Published formal and informal harmonization projects are provided as examples, including lessons drawn from these projects.Citation
Clinics in Laboratory Medicine
Pub Type
Journals
Download Paper
Keywords
LC-MS/MS, protein, harmonization, standardization
Citation
Issues
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Created September 24, 2018, Updated October 13, 2022