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Structural analysis of ligand binding and catalysis in chorismate lyase

January 1, 2006

Author(s)

N. Smith, A. Roitberg, E. Rivera, A. Howard, Marcia J. Holden, M. Mayhew, S. Kaistha, David T. Gallagher

Standards for Autoantibody Testing: Addressing Future Needs for Autoimmune Disease and Cancer Diagnosis

December 17, 2005

Author(s)

Michael D. Amos, A.J. Bridges

It is widely held that determination of increased levels of serum autoantibodies can play an important role in the diagnosis and, in some cases, management of many autoimmune diseases. It is also widely held that such testing is fraught with problems

Repair of Formamidopyrimidines in DNA Involves Different Glycosylases - Role of the OGG1, NTH1, and NEIL1 Enzymes

December 9, 2005

Author(s)

J Hu, N de Souza-Pinto, K Haraguchi, Barbara A. Hogue, Pawel Jaruga, M M. Greenberg, Miral M. Dizdar, V. Bohr

2,6-diamino-4-hydroxy-5-formamidopyrimidine (FapyG) and 4,6-diamino-5-formamidopyrimidine (FapyA), are formed abundantly in DNA of cultured cells or tissues exposed to ionizing radiation or to other free radical-generating systems. We show here that FapyG

Generating Cell Arrays in Microfluidic Networks

October 1, 2005

Author(s)

Samuel P. Forry, D. R. Reyes, Brian J. Polk, Michael Gaitan, Laurie E. Locascio

Vascular smooth muscle cell response on thin films of collagen

October 1, 2005

Author(s)

John T. Elliott, John T. Woodward IV, K J. Langenbach, Alessandro Tona, P. Jones, Anne L. Plant

Testing Candidate DNA Quantitation Standards with Several Real-Time Quantitative PCR Methods

September 29, 2005

Author(s)

Margaret C. Kline, Peter M. Vallone, Amy E. Decker, Janette W. Redman, David L. Duewer, John M. Butler

Reduction in Dentin Permeability Using a Slurry Containing Dicalcium Phosphate and Calcium Hydroxide

September 9, 2005

Author(s)

Ai-Shuan(Maria) Cherng, Shozo Takagi, Laurence C. Chow

Treatments that obdurate dentin tubules have been used for reducing dentin hypersensitivity. This study was to determine the effect of a treatment with a slurry of micron sized calcium phosphate on the hydraulic conductance (Lp) of etched dentin discs in

Heterotrimeric G-protein alpha-Subunit Adopts a "Preactivated" Conformation When Associated with beta-Subunits

August 29, 2005

Author(s)

N G. Abdulaev, T Ngo, C Zhang, A Dinh, D M. Brabazon, K D. Ridge, John P. Marino

Standards and Standardization of Molecular Diagnostics

August 15, 2005

Author(s)

J P. Jakupciak, C D. O'Connell

DNA has become a major target for clinical laboratory testing over the past 5 years, and RNA testing is emerging for infectious disease and gene expression (1). To normalize laboratory results across different technology platforms as well as between

HIV Structural and Biothermodynamics Databases: A Resource for the Pharmaceutical and Biotechnology Industry

August 12, 2005

Author(s)

Talapady N. Bhat, Yadu D. Tewari, H Rodriguez, Robert N. Goldberg

Federal agencies, academia and industries have invested heavily in the development of structural and biothermodynamics data. However, the data are still largely distributed over several public and private archives leading to issues of inadequate

Forensic DNA typing by capillary electrophoresis: using the ABI Prism 310 and 3100 Genetic Analyzers for STR analysis

July 1, 2005

Author(s)

John M. Butler, E Buel, F Crivellente, B R. McCord

Standard Guide for Detection of Nucleic Acid Sequences by the Polymerase Chain Reaction Technique.

July 1, 2005

Author(s)

Prasad T. Reddy, J Toy, Xiao Tang, L E. Bockstahler

Symposium on Metrology and Standards for Cell Signaling: Impact on Tissue Engineering, National Institute for Standards and Technology, October 14-15, 2003

July 1, 2005

Author(s)

Anne L. Plant, E. Horowitz

The Symposium on Metrology and Standards for Cell Signaling: Impact on Tissue Engineering, was held at the National Institute for Standards and Technology (NIST) on October 14-15, 2003. The purpose of the symposium, which was co-sponsored by NIST and ASTM

Functional Reconstitution of Protein Ion Channels Into Planar Polymerizable Phospholipid Membranes

June 1, 2005

Author(s)

D K. Shenoy, W R. Barger, A Singh, R G. Panchal, Martin Misakian, Vincent M. Stanford, John J. Kasianowicz

An Inter-Platform Repeatability Study Investigating Real-Time Amplification of Plasmid DNA

May 25, 2005

Author(s)

C Donald, F Qureshi, M J. Burns, Marcia J. Holden, J L. Blasic, A J. Woolford

Background: Currently, there are many different real-time amplification platforms. However, the results of DNA measurements from experiments performed on different platforms are not necessarily comparable and results may not be repeatable within

Mitochondrial DNA as a cancer biomarker

May 1, 2005

Author(s)

J P. Jakupciak, W. Wang, Maura E. Markowitz, D Ally, Michael D. Coble, Sudhir Srivastava, A Maitra, Peter E. Barker, David Sidransky, Catherine D. O'Connell

Standards for Validation of Cancer Biomarkers

April 2, 2005

Author(s)

Catherine D. O'Connell, Donald H. Atha, J P. Jakupciak

Over the past 10 years, DNA testing to identify disease associated mutations and specific organisms, which represent public health and safety concerns, have become major targets for laboratory testing. RNA testing is also emerging for gene expression, both

Infrared and Raman Spectroscopy Characterization of Biological Products

January 1, 2005

Author(s)

Vytautas Reipa

Both infrared and Raman are increasingly applied in biomolecular structure characterization, thus getting acceptance alongside traditional bioanalytical techniques. Physical principles and biological sampling requirements are reviewed. Advanced

Mouse NEIL1 protein is specific for excision of 2,6-diamino-4-hydroxy-5-formamidopyrimidine and 4,6-diamino-5-formamidopyrimidine from oxidatively damaged DNA

December 21, 2004

Author(s)

Pawel Jaruga, M Birincioglu, T A. Rosenquist, Miral M. Dizdar

Extrinsic factors potassium chloride and glycerol induce thermostability in recombinant anthranilate synthase from Archaeoglobus fulgidus

December 1, 2004

Author(s)

W M. Byrnes, V L. Vilker

Molecular Spectrometry Data Interchange Applications for NIST's SpectroML

December 1, 2004

Author(s)

Anh D. Nguyen, A Arslan, John C. Travis, Melody V. Smith, R Schaefer, Gary W. Kramer

Semiconductor nanocrystal probes for human chromosomes and DNA

December 1, 2004

Author(s)

Yan Xiao, Peter E. Barker

Elastic Flow Instability, Curved Streamlines, and Mixing in Microfluidic Flows

November 5, 2004

Author(s)

Jai A. Pathak, David J. Ross, Kalman D. Migler

Spectroscopic Characterization of Fluorescein- and Tetramethylrhodamine-Labeled Oligonucleotides and Their Complexes With a DNA Template

October 1, 2004

Author(s)

Lili Wang, Adolfas K. Gaigalas, J L. Blasic, Marcia J. Holden

We measured absorption and emission spectra, fluorescence quantum yield, anisotropy, fluorescence resonance energy transfer (FRET), and melting temperature to characterize fluorescein- and tetramethyIrhodamine (TMR)-labeled oligonucleotides in solution and

Substrate binding and the presence of ferredoxin affect the redox properties of the soluble plant D(9)-18:0-acyl carrier protein desaturase

September 23, 2004

Author(s)

Vytautas Reipa, J Shanklin, V L. Vilker