Journals

Input Space Coverage Matters

January 15, 2020

Author(s)

David R. Kuhn, Raghu N. Kacker, Yu Lei, Dimitris Simos

Testing is the most commonly used approach for software assurance, yet it remains as much judgement and art as science. Structural coverage adds some rigor to

Structure of the cell-binding component of the Clostridium difficile binary toxin reveals a di- heptamer macromolecular assembly

January 14, 2020

Author(s)

Xingjian Xu, Raquel Ruiz, Kaylin Adipietro, Christopher Peralta, Danya Ben-Hail, Kristen Varney, Mary Cook, Braden Roth, Paul Wilder, Thomas Cleveland, Alexander Grishaev, Heather Neu, Sarah Michel, Wenbo Yu, Dorothy Beckett, Richard Rustandi, Alex MacKerell, Amedee des Georges, Edwin Pozharski, David Weber

Targeting Clostridium difficile infection is challenging because treatment options are limited, and high recurrence rates are common. One reason for this is

Overshoot Mitigation Using the Reference Governor Framework

January 12, 2020

Author(s)

DJ Anand, Hamid Ossareh, Collin Freiheit

This paper presents a novel reference governor scheme for overshoot mitigation in a tracking control system. Our proposed scheme, referred to as the Reference

Observation of an isomerizing double-well quantum system in the condensed phase

January 10, 2020

Author(s)

Varun Verma, Jascha A. Lau, Arnab Choudhury, Li Chen, Dirk Schwarzer, Alec M. Wodtke

Molecules are quantum objects; therefore, isomerization fundamentally involves quantum states bound within a molecular potential energy function with multiple

Implications of DNA Damage and DNA Repair on Human Diseases

January 10, 2020

Author(s)

Bryant C. Nelson, M Miral Dizdar

Cellular DNA damage is implicated in the etiology and progression of many different types of human disorders and diseases. Much of the current research in the

Experimental Low-Latency Device-Independent Quantum Randomness

January 10, 2020

Author(s)

Yanbao Zhang, Lynden K. Shalm, Joshua C. Bienfang, Martin J. Stevens, Michael D. Mazurek, Sae Woo Nam, Carlos Abellan, Waldimar Amaya, Morgan Mitchell, Honghao Fu, Carl A. Miller, Alan Mink, Emanuel H. Knill

Applications of randomness such as private key generation and public randomness beacons require small blocks of certified random bits on demand. Device

Recent achievements and current interests in research on characterization and quality control of biopharmacueticals in Japan?

January 9, 2020

Author(s)

Akiko Ishii-Watabe, Hiroko Shibata, Hiroyuki Suetomo, Yosuke Ikeda, Srivalli Telikepalli, Masato Kiyoshi, Yu Hayashi, Takashi Muto, Yukako Tanaka, Satomi Ueda, Takafumi Iwura, Satoshi Saitoh, Michihiko Aoyama, Akira Harazono, Masashi Hyuga, Yukihiro Goda, Tetsuo Torisu, Susumu Uchiyama

Detector-Agnostic Phase-Space Distributions

January 9, 2020

Author(s)

Thomas Gerrits, Adriana Lita, Sae Woo Nam, Jan Sperling, David Phillips, Jacob Bulmer, G Thekkadath, A. Eckstein, T Wolterink, J Lugani, Wolfgang Vogel, G.S. Agarwal, Christine Silberhorn, Ian Walmsley

The representation of quantum states via phase-space functions constitutes an intuitive technique to characterize light. However, the reconstruction of such

The impact of the metal interface on the stability and quality of a therapeutic fusion protein

January 9, 2020

Author(s)

Adrian P. Defante, Steven D. Hudson, Cavan K. Kalonia, Emma Keegan, Steven Bishop, Paul Santacroce, Satish Hasige

Subvisible particle formation which occurs after the sterile filtration step of the fill/finish process is challenge that may occur during the development of

Structural stability of Co-V intermetallic phases and thermodynamic description of the Co-V system

January 9, 2020

Author(s)

Peisheng Wang, Thomas Hammerschmidt, Ursula R. Kattner, Olson B. Gregory

The Co-V system has been reviewed. Density functional theory (DFT) calculations using the generalized gradient approximation were used to obtain the energies

Modelling photovoltaic soiling losses through optical characterization

January 9, 2020

Author(s)

Greg P. Smestad, Thomas Germer, Hameed Alrashidi, Eduardo F. Fern?ndez, Sumon Dey, Paidisetty S. Kumar, Honey Brahma, Aritra Ghosh, Nazmi Sellami, Ibrahim A. Hassan, Amal Kasry, Bala Pesala, S. Senthilarasu, Florencia Almonacid, K. S. Reddy, Tapas K. Mallick, Leonardo Micheli

The accumulation of soiling on photovoltaic (PV) modules affects PV systems worldwide. Soiling consists of mineral dust, soot particles, aerosols, pollen, fungi

Materials Characterization With Multiple Offset Reflects at Frequencies to 110 GHz

January 8, 2020

Author(s)

Nina P. Basta, Aaron Hagerstrom, Jasper A. Drisko, James Booth, Edward Garboczi, Christian Long, Nathan Orloff

Understanding the electrical properties of materials is a necessary part of any microwave circuit design. In this article, we explore the possibility of

Organoarsenicals in Seafood: Occurrence, Dietary Exposure, Toxicity, and Risk Assessment Considerations − A Review

January 8, 2020

Author(s)

Caleb Luvonga, Catherine A. Rimmer, Lee L. Yu, Sang B. Lee

Diet, especially seafood, is the main source of arsenic exposure for humans. Total arsenic content provides limited information for evaluation of the

Selective Ethane/Ethylene Separation in a Robust Microporous Hydrogen-Bonded Organic Framework

January 8, 2020

Author(s)

Xu Zhang, Libo Li, Jia-Xin Wang, Hui-Min Wen, Rajamani Krishna, Hui Wu, Wei Zhou, Zhong-Ning Chen, Bin Li, Guodong Qian, Banglin Chen

The separation of ethane (C 2H 6) from ethylene (C 2H 4) is of prime importance in the production of polymergrade C 2H 4 for industrial manufacturing. It is

Ultranarrow linewidth photonic-atomic laser

January 8, 2020

Author(s)

Wei Zhang, Liron Stern, David R. Carlson, Douglas G. Bopp, Zachary L. Newman, Songbai Kang, John Kitching, Scott Papp

Lasers with high spectral purity can enable a diverse application space, including precision spectroscopy, coherent high-speed communications, physical sensing

Database-Assisted Design of Purlins and Girts for Wind Accounting for Directionality

January 8, 2020

Author(s)

Dat Duthinh, Emil Simiu

For the database-assisted design (DAD) of low-rise building purlins and girts, a method is proposed that explicitly accounts for wind directionality by using

Detection Orthogonality in Macromolecular Separations. 2. Exploring Wavelength Orthogonality and Spectroscopic Invisibility Using SEC/DRI/UV/FL

January 7, 2020

Author(s)

Andre M. Striegel, Walter B. Wilson, Lane C. Sander

We continue herein the exploration of detector orthogonality in size-based macromolecular separations. Previously [5], the sensitivity of viscometric detection

Efficient Randomness Certification by Quantum Probability Estimation

January 7, 2020

Author(s)

Emanuel H. Knill, Yanbao Zhang, Honghao Fu

For practical applications of quantum randomness generation, it is important to produce a fixed block of fresh random bits with as few trials as possible

A Precision Measurement of the Neutron Scattering Length of4He Using Neutron Interferometry

January 7, 2020

Author(s)

Robert W. Haun, Fred Wietfeldt, Muhammad D. Arif, Michael G. Huber, T C. Black, Ben Heacock, Dmitry Pushin, Chandra B. Shahi

We report a 0.08% measurement of the bound neutron scattering length of 4He using neutron interferometry. The result is b=(3.0982 ± 0.0021[stat] ± 0.0014[syst])

Microsecond-timescale simulations suggest 5-HT-mediated preactivation of the 5-HT3A serotonin receptor

January 7, 2020

Author(s)

Nicholas B. Guros, Arvind Balijepalli, Jeffery B. Klauda

Aided by efforts to improve their speed and efficiency, molecular dynamics (MD) simulations provide an increasingly powerful tool to study the structure

Structural and Reorientational Dynamics of Tetrahydroborate (BH₄-) and Tetrahydrofuran (THF) in a Mg(BH₄)₂𔅗THF Adduct: Neutron-Scattering Characterization

January 7, 2020

Author(s)

Mirjana NMN Dimitrievska, Marina Chong, Mark E. Bowden, Hui Wu, Wei Zhou, Iffat Nayyar, Bojana Ginovska, Thomas Gennett, Tom Autrey, Craig M. Jensen, Terrence J. Udovic

Metal borohydrides are considered as promising materials for hydrogen storage applications due to their high volumetric and gravimetric hydrogen densities

Perspectives of electrically generated spin currents in ferromagnetic materials

January 7, 2020

Author(s)

Angie Davidson, Vivek P. Amin, Wafa Aljuaid, Paul M. Haney, Xin Fan

Bottom-up Cu Filling of Annular Through Silicon Vias: Microstructure and Texture

January 6, 2020

Author(s)

Thomas P. Moffat, Daniel Josell

Microstructural and morphological evolution during bottom-up Cu filling of TSV in a CuSO4-H2SO4-Cl- poloxamine electrolyte is examined. Deposition proceeds in

Absolute measurement of laser ionization yield in atmospheric pressure range gases over 14 decades

January 6, 2020

Author(s)

Daniel Woodbury, Robert Schwartz, Ela Rockafellow, Jared Wahlstrand, H M. Milchberg

Multiphoton and tunneling ionization are fundamental processes in strong field laser-matter interactions, and are integral to applications such as high harmonic

Unwinding twenty years of the archaeal minichromosome maintenance helicase

January 6, 2020

Author(s)

Lori M. Kelman, William Brad O'Dell, Zvi Kelman

Collisions of room temperature helium with ultra-cold lithium and the van-der-Waals bound state of HeLi

January 6, 2020

Author(s)

Constantinos Makrides, Daniel Barker, James A. Fedchak, Julia Scherschligt, Stephen Eckel, Eite Tiesinga

We have computed the thermally-averaged total, elastic rate coefficient for the collision of a room-temperature helium atom with an ultra-cold lithium atom

Covariance-based uncertainty analysis of reference equations of state

January 6, 2020

Author(s)

Howard Cheung, Jerome Frutiger, Ian Bell, Jens Abildskov, Gurkan Sin, Shengwei Wang

This work presents a detailed methodology for uncertainty analysis applied to a reference equation of state (EOS) based on Helmholtz energy. With increasing

Quantifying protein aggregation kinetics using electrospray differential mobility analysis

January 5, 2020

Author(s)

Kaleb J. Duelge, Jeremie Parot, Vincent A. Hackley, Michael R. Zachariah

Protein aggregation is a significant concern in bioprocessing and end use applications. Here the thermal aggregation kinetics of bovine serum albumin (BSA) and

Focused Ion Beam-Induced Displacive Phase Transformation From Austenite to Martensite during Fabrication of Quenched and Partitioned Steel Micro-Pillar

January 5, 2020

Author(s)

Eun Jung Seo, Lawrence Cho, Jin Kyung Kim, Javad Mola, Lijia Zhao, Sukjin Lee, Bruno C. De Cooman

We report evidence of displacive phase transformation from retained austenite to martensite during preparation of quenched and partitioned steel micro-pillars

Development of an LC-APCI-MS Method for Determining Off-Flavor Compounds and its Application Towards Marine Recirculating Aquaculture System Monitoring and Evaluation of Aeration as a Depuration Approach

January 4, 2020

Author(s)

Mary Bedner, Keiko Saito

The off-flavor compounds geosmin and 2-methylisoborneol (2-MIB) are well-known to impact the quality of farmed freshwater fish species, but little is known