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MfgTech Roadmap - Supply Chain Resilience
In the last two years, manufacturers in the United States have experienced forced disruptions and many people have seen the impact. Innovations in supply chain resilience will enable U.S. manufacturers to improve operational efficiency and effectiveness, produce quality goods and vaccines, rapidly identify supply-chain disruptions and quality issues, and strengthen national security.
|
Title |
Recipient |
Federal Funds |
|
Freeze-Thaw and Aseptic Drying Technology Roadmap for Pharma/Biotech Manufacturing |
Purdue University |
$296,155 |
|
Developing a Roadmap to Strengthen the U.S. Manufacturing Supply Chain via the Digital Thread |
Commonwealth Center for Advanced Manufacturing |
$300,000 |
Freeze-Thaw and Aseptic Drying Technology Roadmap for Pharma/Biotech Manufacturing
 |
Leading Organization |
Partners: |
|
Purdue University (IN) |
|
Deliverables:
Support the AMTech-funded LyoHUB consortium in expanding their existing technology roadmap that aims to strengthen pharmaceutical cold chain and aseptic drying technologies.
- Address new product modalities such as mRNA vaccines, cell and gene therapies
- Include freeze-thaw and alternative aseptic drying technologies
- Create infrastructure for roadmap implementation projects and workforce training on current and emerging technologies.
Activities:
- Convene a series of workshops that will bring together industry members representing the broader freeze-thaw and aseptic drying value chain along with representatives from government, academia, and professional societies.
- Publish the LyoHUB 2.0 roadmap on the consortium website and in a series of technical articles in open access journals for free public access.
Potential Impacts:
Development of new methods to stabilize drug products to more rapidly deploy therapeutics to meet public health needs. The advancement of freezing and aseptic drying technologies will strengthen the country’s pandemic readiness and will secure access of the U.S. public to life-saving medicines.
Period of Performance:
April 1, 2022 – September 30, 2023
Developing a Roadmap to Strengthen the U.S. Manufacturing Supply Chain via the Digital Thread
 |
Leading Organization: |
Partners: |
|
Commonwealth Center for Advanced Manufacturing (VA) |
|
Deliverables:
- Develop a technology roadmap to improve the resilience and capacity of the U.S. manufacturing supply chain through the digital thread.
- Identify critical weaknesses and gaps in digital thread technology to develop a tangible, actionable, industry-driven document that will guide research and enable effective adoption of digital thread technology throughout the extended supply chain.
Activities:
- Conduct stakeholder interviews, site visits, surveys and substantive literature reviews.
- Host and facilitate collaborative work sessions to develop roadmap priorities through collaborative ideation, critical design thinking, and consensus building activities throughout the project.
Potential Impacts:
Enable U.S. manufacturers to improve operational efficiency and effectiveness, produce higher quality goods, rapidly identify supply-chain disruptions and quality issues, and expand revenue opportunities.
Period of Performance:
April 1, 2022 – March 31, 2023