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MfgTech Roadmap - Supply Chain Resilience
U.S. manufacturers have faced significant disruptions in recent years, and the impact is clear to producers and purchasers. By embracing innovative solutions for supply chain resilience, manufacturers are poised to enhance their operational efficiency and effectiveness. These improvements will enable the rapid identification of supply chain disruptions and quality concerns and bolster national security.
| Title | Lead Organization |
| Freeze-Thaw and Aseptic Drying Technology Roadmap for Pharma/Biotech Manufacturing | Purdue University |
| Developing a Roadmap to Strengthen the U.S. Manufacturing Supply Chain via the Digital Thread | Commonwealth Center for Advanced Manufacturing |
Freeze-Thaw and Aseptic Drying Technology Roadmap for Pharma/Biotech Manufacturing
| Leading Organization | Partners: |
| Purdue University (IN) |
|
Period of Performance:
April 1, 2022 – September 30, 2023
Accomplishments:
- Identified two broad areas of effort needed to move toward the goal of high-quality, lower-cost, and more readily available lyophilized products: (1) advancing lyophilization technologies and techniques and (2) strengthening the industry foundation.
- To advance lyophilization technologies and techniques, it was determined that technical innovations will be required in lyophilized products, the lyophilization process, and lyophilization equipment.
- To strengthen the industry foundation, it was determined that the interface between the industry and regulatory agencies must be strengthened for interagency communication and information dissemination and that a well-trained workforce be developed and maintained
Developing a Roadmap to Strengthen the U.S. Manufacturing Supply Chain via the Digital Thread
| Leading Organization: | Partners: |
Commonwealth Center for Advanced Manufacturing (VA) |
|
Publication Date: October 2024
Accomplishments:
- Identified critical weaknesses and gaps in digital thread technology, resulting in the development of a comprehensive, actionable document that can guide research efforts and facilitate the effective adoption of digital thread technology throughout the extended supply chain.
- Proposed focused investment in specific “solutions” rooted in Digital Thread technology to address supply chain resilience and capacity issues
- Proposed a standards-based Digital Thread technology framework to enable composable, interoperable, and secure solutions that can cost-effectively address many use cases across multiple industry sectors.
For more information, visit: https://doi.org/10.6028/NIST.GCR.24-057