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Material Measurement Laboratory /Biomolecular Measurement Division

Biomolecular Structure and Function Group

The Biomolecular Structure and Function Group advances new measurement methods and modeling tools for structural analysis of biomolecules and biomolecular complexes.

In collaboration with U.S. industry, government agencies, and scientific institutions, the Biomolecular Structure and Function Group develops precision measurement and modeling tools and standards to support determination of biomolecular structure, dynamics, energetics and function.  The group also advances innovative approaches for engineering biological systems to support applications in biotechnology and bioscience research.  

Our group is located at the Institute for Bioscience and Biotechnology Research (IBBR), a joint institute of the University of Maryland and NIST.  For information on group activities please visit IBBR. 

News and Updates

Projects and Programs

Bioman lifecycle

Biomanufacturing Program

Ongoing
The NIST Biomanufacturing Initiative is designed to bolster the U.S. biopharmaceutical industry by providing the measurement science, standards, and analytical tools necessary to produce high-quality, low-cost protein drugs. The program focuses on the entire bioprocess lifecycle, aiming to foster...
component 1

Consistency Analysis and Uncertainty in ‘omic Data

Ongoing
‘Omics is increasingly moving out of the laboratory and towards use in industrial and commercial applications. For instance, in biomanufacturing, there is a need for quality control when developing biotherapeutics, which will almost certainly require a machine-learning classifier to separate...
Cryogenic electron microscopy (cryo-EM) image of an LNP/RNA formulation

LNP-RNA Research Grade Test Material

Ongoing
The currently planned LNP/RNA material (designated RGTM 10240) will include a fragment of the SARS-CoV-2 genome that is approximately 4 kb in length. This fragment was previously included (in unencapsulated form) as “Fragment 1” of NIST RGTM 10169. The RNA fragment is not designed for cell-based...

Publications

Awards

Press Coverage

Contacts

Group Leader

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