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Organic Chemical Metrology Group

The Organic Chemical Metrology Group is responsible for developing, critically evaluating, and applying liquid chromatographic, gas chromatographic, spectroscopic and mass spectrometric techniques for the confident identification and measurement of organic species in a variety of matrices.


The Organic Chemical Metrology Group (OCMG) develops, critically evaluates, and applies analytical methods based on liquid chromatography, gas chromatography, high-resolution mass spectrometry, multidimensional chromatographic separation procedures, vibrational and nuclear magnetic resonance spectroscopy, as related to analyses at trace and ultratrace concentration levels.  The OCMG designs, produces and maintains an extensive portfolio of Standard Reference Materials and data products, primary standards, and Quality Assurance programs for organic species in clinical, nutritional assessment and metabolomics, food safety and nutrition, dietary supplement and natural products, chemical manufacturing, and forensics program areas. The group provides advice and measurement services to other government agencies, scientific organizations, and US industry; and engages with international standards organizations and other National Metrology Institutes (NMIs) to establish comparability of measurement capabilities.


News and Updates

Standards for Tracking PFAS Contaminants

Aqueous film forming foams (AFFFs) containing PFAS have been used since the 1960s for fire control and training for aviation crash and jet fuel spills at

Latest Publications

Certification of Standard Reference Material® 1595a Tripalmitin

Michael Nelson, Jerome Mulloor, Brian Lang, Blaza Toman, Antonio Possolo, William Perry, Alicia Lyle
Standard Reference Material (SRM) 1595a Tripalmitin is a high purity chemical substance having a certified value for purity, expressed as a mass fraction. It is



Providing automated, virtual assistance in statistics for chemical analysis The NIST ABACUS ( App for Bayesian Analysis of Chemical quantities Using Shiny) is

Simulated Chromatographic Data

The following information is provided as an aid in the validation of mathematical models used in quantitation with chromatographic data. This data may also be


Group Strat Award

Christina Jones, Benjamin Place and Aaron Urbas, together with CSD colleagues Regina Easley, Jason Waters, Laura Wood, Lee Yu, David Sheen and Werickson Rocha, received the 2019 MML Strategic Partnership Award for the establishment of a multidisciplinary team to conduct metrology research at NIST as part of the European Erasmus Mundus Joint Master in Quality in Analytical Laboratories (EMQAL) program.
PS1 group

Michael Nelson and Katrice Lippa, together with NIST colleagues Brian Lang, Jason Waters and Blaza Toman, received the Cooperation on International Traceability in Analytical Chemistry (CITAC) Best Paper Award for 2018 for their work on “A New Realization of SI for Organic Chemical Measurement: NIST PS1 Primary Standard for Quantitative NMR (Benzoic Acid)”.

Press Coverage

Featured Videos

NIST Chemist Melissa Phillips on Carbon
NIST Chemist Melissa Phillips on Carbon
NIST Analytical Chemistry Supports Industry and Health
NIST Analytical Chemistry Supports Industry and Health


Group Leader

Office Manager