We provide the measurement science, standards, technology, and data required to support the nation's needs in determining the composition, structure, quantity, and function of proteins, peptides, post-translational modifications such as glycosylation and phosphorylation, and related biomolecules such as metabolites. In partnership with U.S. industry, government agencies, and scientific institutions, the group performs fundamental and applied research on the characterization and quantitation of proteins, peptides, and their mixtures using techniques such as mass spectrometry, liquid chromatography, electrophoresis, and immunoassays. The Group provides measurement science, reference materials, reference data, and technologies to support accuracy and comparability of measurements needed to advance biotechnology, biomedical and bioscience research, biomanufacturing, and health care. Specific areas of interest include measurements and standards for clinical diagnostics and biotherapeutics.
The National Institute of Standards and Technology (NIST) has issued one of the world’s most intricate measurement standards: an exhaustively analyzed antibody protein that the biopharmaceutical industry will use to help ensure the quality of treatments across a widening range of health conditions, including cancers, autoimmune disorders and infectious diseases. Read More