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Protein drugs are the top selling pharmaceuticals worldwide, a hundred billion dollar industry, but also the fastest growing category of health care costs. The
The use of metabolite, lipid, and protein profiles for systems biology, biomedical research, and clinical applications has risen dramatically over recent years
NIST is developing methods for the quantification of clinically-relevant protein biomarkers by mass spectrometry. Some methods are intended to establish
C-reactive protein (CRP) levels in serum or plasma have been used as an indicator of inflammation and infection. Recent evidence also suggests that CRP levels
Cardiac troponin I (cTnI) is considered the 'gold standard' for the diagnosis of myocardial infarction and the assessment of cardiac damage. Yet this clinical
Proteins are established markers of health or disease status in clinical samples, and commercial assays have been developed to measure these proteins in a
Serum proteomics, the detection and measurement of as many proteins in a serum sample as possible, could be an important element of personalized medicine
Proteins are of significant interest as potential indicators (biomarkers) of health or disease. Clinical methods employed to measure these analytes are often
The NIST Food Protein Allergen Program is focused on providing reference materials and methods to improve the connection between the measured protein food
NOW AVAILABLE The NIST monoclonal antibody (NISTmAb) reference material, RM 8671, is intended for use in evaluating the performance of methods for determining
The NIST Urine Albumin Standardization Program is focused on the development of a measurement procedure and reference materials to support an international
Membrane proteins constitute approximately 30% of all cellular proteins. Nevertheless, this group of proteins is traditionally understudied due to limitations