Microbial measurements

News and Updates

Identifying Individual Molecules: NIST Study Suggests How to Build a Better ‘Nanopore’ Biosensor

April 27, 2021

Researchers have spent more than three decades developing and studying miniature biosensors that can identify single molecules. In five to 10 years, when such

Spotlight on N-STEP Graduates

February 18, 2020

NIST’s Science and Technology Entrepreneurship Program (N-STEP) was created by the company, TEDCO, whose mission is to “Enhance economic development growth

Unusual Suspects

March 16, 2018

NIST contributes to public safety with materials that increase the confidence of first responders to detect biothreats in the field. NIST’s Material Measurement

Projects and Programs

DARPA Friend or Foe (FoF) -- Independent Verification and Validation (IV&V)

The development of new platforms for characterization of complex microbial samples are hampered by lack of reproducibility and comparability across different

Pathogen Detection and Identification in the Clinical Setting: The Next Generation of Analyses

NIST and FDA are co-developing DNA-based materials for mixed microbial detection. Our annual workshop brings together private and public interests to discuss

NIST Living Measurement Systems Foundry

The goal of the NIST Living Measurement Systems Foundry is to enable the engineering of cells for reliable and safe use in dynamic and unpredictable

RM 8376 Microbial Pathogen DNA Standards for Detection and Identification

Metagenomic Next Generation Sequencing (mNGS) promises to revolutionize infectious disease diagnostics. However, the analytical performance of this technology

Publications

The mutation spectrum shapes the spectrum of adaptive substitutions

May 20, 2021

Author(s)

Alejandro Cano, Hana Rozhonova, Arlin Stoltzfus, David McCandlish, Joshua Payne

Evolutionary adaptation can be conceived as a series of substitutions representing mutation-fixation events. The changes that are more likely will appear more

Organizing genome engineering for the gigabase scale

February 9, 2021

Author(s)

Bryan A. Bartley, Jacob Beal, Jonathan R. Karr, Elizabeth A. Strychalski

Engineering an organism's entire genome enables large-scale changes in organization, function, and environmental interactions, with significant implications for

Niche partitioning of microbial communities at an ancient vitrified hillfort: implications for vitrified radioactive waste disposal

August 31, 2020

Author(s)

Jamie L. Weaver, Andrew Plymale, Jacqueline Wells, Carolyn I. Pearce, Colin Brislawn, Emily Graham, Tanya Cheeke, Jessica Allen, Vincent Danna, Kimberly Tyrrell, Rolf Sjoblom, Edward Vicenzi, John McCloy, Eva Hj?rthner-Holdar, Erik Ogenhall, Mia Englund, David Peeler, Albert Kruger, Rick L. Paul

A pre-Viking era vitrified hillfort, Broborg, provides a habitat analogue for disposed radioactive waste glass and shows strong niche partitioning among the

From Patient to Laboratory: Challenges in Developing Standardized Measurements for the Microbiome

January 27, 2020

Author(s)

Heidi Leonard, Scott A. Jackson, Leigh A. Frame

The communities of microorganisms living within and on us collectively constitute our microbiome. The microbiome has been linked to numerous health problems