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Projects/Programs

Topic Area
Displaying 476 - 500 of 1655

Engineered Materials for Resilient Infrastructure Program

Ongoing
Objective - To develop and deploy measurement science to reliably assess the current and future performance of engineered materials in support of resilient infrastructure given exposure to chronic (e.g., materials degradation) and episodic (e.g., earthquakes) hazards. What is the technical idea? To
Map of the world with the engineering biology topics covered in Americas, Europe, and Asia meetings

Engineering Biology Metrics and Technical Standards for the Global Bioeconomy

Ongoing
Stakeholders from the Americas, Asia and Australia, and Europe and Africa, came together through a series of regional workshops in Washington D.C., Singapore, and Brussels, respectively, to identify specific areas for development, both technical and non-technical towards continued scale-up and economic growth across the bioeconomy.

Engineering Living Measurement Systems to Sense PFAS

Ongoing
Per- and polyfluoroalkyl substances, PFAS, are thermodynamically stable organic fluorinated chemicals that are resistant to traditional degradation pathways leading to concern for bioaccumulation. These compounds originate from several industrial manufacturing processes and are found in soil systems
Electron micrographs of representative as-synthesized MNPs for thermometry.

Engineering and Optical Characterization of Magnetic Nanoparticles (MNPs)

Completed
Nanomagnets by Design Nanoparticles are an important subclass of low-dimensional magnetic materials displaying size-dependent magnetic behavior. The controllable magnetocrystalline anisotropy introduced at nanoscale size regimes (as low as 3 nms in diameter) allows for MNPs of ferro/ferrimagnetic
GPCR

Engineering of G Protein-Coupled Receptors

Ongoing
A trait of all life is the ability to sense and respond to changing environments, and the largest family of eukaryotic proteins that sense and respond to extracellular signals are called G Protein-Coupled Receptors (GPCRs). In humans, over 800 GPCRs detect a wide range of biological and chemical
STM image of a 28-Si film deposited onto a Si/100 substrate

Enriched Silicon and Devices for Quantum Information

Ongoing
Enriching silicon from 5% to <1 ppm 29Si Groundbreaking work around the world has realized qubits in silicon using metal-oxide-semiconductor (MOS) devices, single atomic dopants/defects and SiGe heterostructures, and, in all cases, the qubit coherence and fidelity properties are improved when using

Environmental Leaching of Nanoparticles from Consumer Products

Ongoing
New nanotechnology-based consumer products are currently entering the market at a rate of 3 or 4 per week, and it is estimated that $2.6 trillion in manufactured goods will contain nanotechnology by 2014. Unfortunately, the overall safety of short- and long-term exposure to nanoparticles and the
Photo with a person making notes on the notepad and superimposed graphics of check boxes and charts

Environmental Metrology Measurement Assistant (EMMA)

Ongoing
Quantification of environmental metrology data can be complex at the level on which NIST operates. Projects often include dozens of samples from multiple matrices and can target well over 300 analytes of vastly different chemical properties, each of which must be individually assessed. Quality

Environmental: NIST Radiochemistry Intercomparison Program (NRIP)

Ongoing
The NRIP includes five matrices (acidified water, air filters, soil, synthetic urine and synthetic feces) of test samples spiked with a well-characterized solution that contains alpha-, beta-, and gamma-emitting radionuclides (see Table 1). The NRIP participants decide which radionuclides they will

ERCC 2.0: Developing a New Suite of RNA Controls

Completed
Requested RNA Control products include: Transcript isoforms; New and improved messenger RNA mimics and mixture formulations; microRNA and other small RNA molecules; and Cancer fusion transcripts. ERCC technical working groups are developing design specifications, RNA control products, and analysis

e-Statistics

Ongoing
DESCRIPTION: e-FITS is a web-based tool, currently available to NIST staff, used to perform the following tasks for over 100 probability distributions. Generate graphs of probability functions (probability density, cumulative distribution, inverse cumulative distribution, hazard, cumulative hazard
Harnessing EUV capabilities for non-destructive metrology

EUV Scatterometry

Ongoing
To measure and inspect the smallest printed features on an IC chip, researchers and manufacturers use a combination of electron scanning modalities (i.e., transmission electron and scanning electron microscopies) and an optical method, scatterometry. Industrially, the most common modality for
Zone Plate Schematic

EUV Zone Plates for Compact Solar Radiometer

Ongoing
A zone plate is an optical element used to separate and focus individual wavelengths of light. The zone plate consists of small circular rings that are opaque to the light separated by gaps, which are transparent. The incident light diffracts from the zone plate at an angle that depends on the
microfluidic chip

Evaluating Measurement Quality of Microfluidic Cell-based Assays

Completed
Impact and Customers Our work establishes metrics for measurement quality and reproducibility for cell-based assays within microfluidic devices. Many novel microfluidic devices are being created that permit new measurements or enable new biological functions to be tested; however, characterizations
A time series of a MoS2 flake exposed to increasing time under electrical stress shows the growth of defects denoted with red and yellow areas over time. S= source and D = drain electrode.

Evaluation of 2D and WBG Material Quality Toward Device Reliability

Ongoing
Two-dimensional (2D) and wide band gap (WBG) materials are some of the latest materials classes having the potential to be transformative because of their high carrier mobilities, tunable bandgap, and atomic-scale film thicknesses. Unexpected degradation and failure in device performance is often
Organic light emitting diode, light output is modulated through magnetic control of exciton states

Exciton and Charge Transport Dynamics in Organic Semiconductors

Ongoing
Our approach toward establishing connections between the application space and physical phenomena includes developing electrical/optical devices and measurements that can be used for physical measurement, physical measurements that can be applied to real devices, and device design that can be tuned

Experimental Evaluation of Large-Scale Parallel Measurement Systems

Ongoing
DESCRIPTION: An archetype among biological experiments is gene-by-gene determination of the expression difference between two groups of biological units. For each gene, the experiment yields a data set consisting of one or more expression values for each unit. Gene to gene, these data sets can be
Graphic of a head shadowed by another head in blue and the inner head has where the brain would be has gold points with gold lines connecting them and there is a blue and gold double helix representing DNA on the left bottom of a circle going around both heads.

Expert Working Group on Human Factors in Forensic DNA Interpretation

Completed
Forensic DNA interpretation is widely regarded as a critical tool in modern criminal investigations, often seen as the gold standard of forensic evidence due to its potential to help link individuals to crime scenes. The process begins with the collection and preservation of DNA samples—from blood

Explainable Artificial Intelligence Based Modeling Applied to OMICS Problems

Ongoing
The goal of the project is to produce billions of certified values from multiple measurement methods with well-characterized uncertainty in the “’omics” field (genomics, proteomics, transcriptomics). These values are prepared by a joint effort between human experts and trained AI based models for
Ammunition metal box with explosives sticker.

Explosives Decomposition Chemistry

Completed
Intended Impact Computational modeling and simulation will help in the invention of new explosives, the design of compounded mixtures of existing materials, and the engineering of delivered systems such as military ordnance. Objective Detailed chemistry is a necessary part of computational
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