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Material Measurement Laboratory

Projects/Programs

Displaying 401 - 425 of 569
]: Photograph of two vials containing human milk Standard Reference Materials.

Organic Compounds in Human Serum, Milk, and Urine

Ongoing
Standard Reference Materials (SRMs) have been specifically designed to assist in the quality assurance measurements for compounds found in human fluids. Clinical and biomonitoring laboratories rely on these SRMs for method validation and as control materials during specific analyses. Various human

Orthogonal Measurements

Ongoing
Definitions: Orthogonal measurements: Measurements that use different physical principles to measure the same property of the same sample with the goal of minimizing method-specific biases and interferences. Complementary measurements: Measurements that corroborate each other to support the same
Photo montage with images of a sea turtle, sea lion, whale, and dolphins.

Pacific Marine Mammal Health Assessments (PMMHA)

Completed
Pacific Marine Mammal Health Assessments (PMMHA), which began in Fall 2010, are an expansion of NIST marine mammal health assessment collaborations that began in 2002 with bottlenose dolphin wild populations. NIST has a history of involvement in marine mammal health assessment related work

Particles, Tubes, and Colloids

Ongoing
Description A highlight of the PTC project is our success in purification of well-defined SWCNT populations using liquid phase separation methods. Although we use multiple techniques and methods, ion exchange chromatography, rate-zonal and isopycnic ultracentrifugation, size exclusion chromatography

Pathogen Detection and Identification: The Next Generation of Analyses

Ongoing
Human disease resulting from pathogens represents a tremendous burden on the health care system. Many hospitals have adopted new, rapid polymerase chain reaction (PCR)-based detection systems because the time to diagnose and begin effective treatment has a direct impact on patient survival and

Peptide Mass Spectral Libraries

Ongoing
Intended Impact Modern mass spectrometers used in the field of proteomics are capable of profiling thousands of peptides in a single experiment. Each of these peptides is fragmented to form a mass spectrum. Therefore, interpretation of these mass spectra is a critical step in the experimental
Photo montage showing fill the airplane with fire-fighting foam, a spilled glass of wine on the tablecloth. Cleaning clothes and furniture from stains, Discarded Fast Food Wrappers Littered on Ground, wateproof jacket with water droplets on it. Jacket using the gore-tex technology.

Per- and Polyfluoroalkyl Substances (PFAS)

Ongoing
Perfluorinated and polyfluorinated alkyl substances (PFAS) constitute a family of compounds that are distinguished by partial or complete fluorination of alkyl hydrocarbons. Dubbed “forever chemicals”, the unique chemistry of PFAS imparts a high level of stability, making the compounds resistant to
Illustrated cube has crystal framework in gray with red balls interspersed in the open spaces.

Performance Metrics for Industrial Gas Separation and Purification

Ongoing
Sorbents in Direct Air Capture (DAC) are exposed to the atmosphere, where they adsorb CO2 then are isolated from atmosphere, the CO2 is driven off by heating or pulling vacuum, refreshing the sorbents. This adsorption-refresh cycle depends not only on the competitive adsorption of CO2 with the other

Performance Metrics for Proteomics

Ongoing
Intended Impact Proteomics experiments designed to identify protein markers specific to a particular disease or disease state rely on repeatable identification of proteins within a control set. Repeatability provides statistical assurance that clear differences between two sets (e.g. sick vs

Personal Body Armor

Completed
To quantify the impact of mechanical degradation on ballistic fibers, NIST developed a novel device for controlled folding of yarns and woven fabrics. In addition, we developed test protocols that employ single fibers to assess the effect of folding using a recently developed modified single fiber
An image showing the hybrid AFM + SLA system from the SPM4AMP project

Photopolymer Additive Manufacturing

Ongoing
NEWS September 2021: NIST and Radtech have launched a Photopolymer Additive Manufacturing Alliance (PAMA) to advance strategic goals for research, sustainability, and regulation in PAM. PAMA is on a mission to make photopolymer additive manufacturing (PAM) more accessible and to increase the safe
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Photopolymerization for Biomaterials

Completed
This project responds to priorities of National Institute of Dental and Craniofacial Research (NIDCR/NIH) for oral health by establishing clinical guidance/standards for adequate photocuring of restorative dental composites. Also, this project is intended to advance the knowledge relevant to thermal

Physical Infrastructure: Connections

Completed
The NIST Physical Infrastructure Program will provide the critical measurement science needed to assess the condition of aging physical infrastructure and guide cost-effective strategies for its maintenance, repair, and replacement. Infrastructure management challenges in the U.S. have received
Running crack in a buried pipeline.

Pipeline Safety

Ongoing
The U.S. operates more than 2.5M miles of natural gas, petroleum and hazardous liquid pipelines, crossing all 50 states and operated by more than 3,000 companies. Fluid hydrocarbon fossil fuels remain the world leading source of energy. The safest and most reliable means of transporting these fuels

Plasma Process Metrology

Ongoing
Intended Impact The model for rf bias effects that we have developed should make it easier for industry to select optimal operating frequencies and may stimulate the adoption of new methods for RF biasing, such as multiple-frequency bias and non-sinusoidal bias. NIST studies of electrical endpoint
Point-of-Care Pharmaceutical Manufacturing

Point-of-Care Pharmaceutical Manufacturing & Precision Medicine

Ongoing
We are employing quality by design (QbD) and risk assessment (cause-and-effect) approaches to investigate production technologies ( e.g., drop on demand or inkjet printing platforms) and appropriate analytical control strategies for point-of-care manufacture of narrow therapeutic index drugs
Materials Extrusion Additive Manufacturing

Polymer Advanced Manufacturing and Rheology

Ongoing
We are measuring the fundamental processes and material parameters that are critical to understanding and furthering polymers-based AM. These efforts will aid the AM ecosystem through better online monitoring capabilities and developing strategies for materials optimization. In situ measurements of

Polymer Analytics

Ongoing
This project focuses on a variety of activities to achieve the aforementioned goal of accelerating the discovery of new polymer physics. Polymer databases In collaboration with partners, we build FAIR (findable, accessible, interoperable, reproducible) data resources that enable machine learning
Composite Interphase

Polymer Composites

Ongoing
Measurements of interphase properties are extremely challenging, and their effects on macroscopic properties and performance of composites are poorly quantified. The objectives of this project fall into the following four research thrusts: Fluorescence Based Probes to Sense Damage and Water in

Polymer Formulations

Completed
Bringing new and optimized formulated products to market requires measurements that will allow rapid assessment of the structure and properties of multicomponent mixtures over large parameter spaces. To this end, we are developing microfluidic "lab on a chip" technologies that enable researchers to
High Impact Ballistic Testing of Polymer Films

Polymer Mechanics

Ongoing
The mechanical behavior for polymers is very sensitive to the deformation rate of the impact test. Thus we are developing and applying several novel measurements that can study the mechanical response of the polymer at different deformation rates and at different material length scales. High-rate
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