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Material Measurement Laboratory / Chemical Sciences Division

Biochemical and Exposure Science Group

Projects/Programs

Displaying 1 - 16 of 16
Hexagon containing words “environmental metabolomics” with arrows pointing from the hexagon to each of the following images: coral, shrimp, mussel, microbe, horseshoe crab, plant. The circle figure has waves and a tree faded in the background.

Applications in Metabolomics

Ongoing
The application of metabolomics techniques to systems biology reveals insights into model and non-model organism biology. The natural world contains undiscovered chemicals and mechanisms that can be harnessed by industry to create new biomanufacturing processes and products. Each biological system...
Photograph of the exterior of the Hollings Marine Laboratory (HML), with signs designation the facility.

HML Organic Chemical Metrology Program Areas

Ongoing
The organic analytical facility, located on the second floor of the Hollings Marine Laboratory, consists of two laboratories with a combined area of approximately 215 m2. These two laboratories provide the space and instrumentation to achieve two main functions for NIST: (1) the determination of...
Map of the world, with six colors used to identify the six regional metrology organizations.

International Comparisons for Chemical Measurements

Ongoing
International agreements and decisions concerning trade and our social well-being increasingly require mutual recognition of measurements and tests among nations. The Mutual Recognition Arrangement (MRA) on national measurement standards and calibration and measurement certificates issued by NMIs...
Main image is a partial periodic table with a blue background, with a graphic overlay of an atom in the bottom left corner.

Isotope Metallomics Quality Assurance Program (IMQAP) Consortium

Ongoing
The use of stable metal isotopes in the health and medical sciences, known as Isotope Metallomics, shows promise for developing clinical biomarkers and improving diagnostics and prognostics. This field is grounded in the idea that certain pathologies trigger physiological responses which lead to...
]: Photograph of two vials containing human milk Standard Reference Materials.

Organic Compounds in Human Serum, Milk, and Urine

Ongoing
Standard Reference Materials (SRMs) have been specifically designed to assist in the quality assurance measurements for compounds found in human fluids. Clinical and biomonitoring laboratories rely on these SRMs for method validation and as control materials during specific analyses. Various human...
Photo montage showing fill the airplane with fire-fighting foam, a spilled glass of wine on the tablecloth. Cleaning clothes and furniture from stains, Discarded Fast Food Wrappers Littered on Ground, wateproof jacket with water droplets on it. Jacket using the gore-tex technology.

Per- and Polyfluoroalkyl Substances (PFAS)

Ongoing
Perfluorinated and polyfluorinated alkyl substances (PFAS) constitute a family of compounds that are distinguished by partial or complete fluorination of alkyl hydrocarbons. Dubbed “forever chemicals”, the unique chemistry of PFAS imparts a high level of stability, making the compounds resistant to...
Steroid Hormone Pathway Mapping

Steroid Hormone Suite Analysis

Ongoing
Steroid hormones are signaling molecules that are major regulators of development, reproduction, stress, and growth. Steroids are synthesized from cholesterol through a series of enzymes, resulting in hormones with distinct biological activities. Although hormones are similar in structure, and...
Fish on a ruler to measure length, about 47 cm from head to tail.

Technological Advances in Aquaculture

Ongoing
According to the NOAA Fisheries of the U.S. report, in 2020 U.S. seafood consumption was estimated at ~6B pounds (~2.7 x 109 kg). Of that, 85% is imported and U.S. exports have seen a significant decline. Globally, the U.S. ranked only 18th in aquaculture production (2020). NIST aims to enhance the...
Dart biopsy collection from a free-ranging bottlenose dolphin

Vertebrate Endocrine Metrology in Non-Traditional Matrices

Paused
NIST collaborates with stakeholders to develop techniques for measuring hormone levels as part of animal health assessment. The process of capturing and transporting animals before sampling can induce stress, which may alter the hormone levels in the bloodstream. Therefore, the collection of blood...
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