Image & signal processing

News and Updates

New Device Design Brings Unparalleled Confidence to Cell Measurements

July 20, 2022

Measuring the numbers and properties of cells moving in a stream — a process called flow cytometry — is critically important to diagnostic medicine

Human figure stands facing large wooden board. Behind that is a row of tubes sticking up from a base.

NIST Method Uses Radio Signals to Image Hidden and Speeding Objects

June 25, 2021

Researchers at the National Institute of Standards and Technology (NIST) and Wavsens LLC have developed a method for using radio signals to create real-time

Escape From Flatland: Calibration Method Enables Microscopes to Make Accurate Measurements in All 3 Dimensions

June 24, 2021

Conventional microscopes provide essential information about samples in two dimensions — the plane of the microscope slide. But flat is not all that. In many

Projects and Programs

GadInk filled neutron transmission grating

Interferometry: INFER - Neutron Interferometric Microscopy of Small Forces and Hierarchical Structures

Ongoing

Multi-scale Images and Hierarchical Structures One of the keys identified by the 2015 DOE report, “Challenges at the Frontiers of Matter and Energy: Transformative Opportunities for Discovery Science” are methods that can study hierarchical systems. Such systems include the propagation of

Optical and Optoelectronic Materials Characterization

Ongoing

Today's electronics have reached a point where sheer computation power has combined form and function as the key driver of large consumer markets. The demand for portable and pervasive electronics with greater functionality promises significant changes over the next decades in how society interacts

Quantitative, Traceable Determination of Cell Viability Using Absorbance Microscopy

Ongoing

The current gold standard for cell viability measurements is the trypan blue assay. Trypan blue dye enters dead cells that have a ruptured membrane. As a result, the dead cells are stained blue. Live cells with an intact membrane, on the other hand, do not absorb the dye molecules and remain

Quantum Bioimaging

Ongoing

Our efforts in BBD are focused on using the quantum nature of light to facilitate enhanced and novel measurement technologies for biological samples. For example, so-called bright squeezed laser sources enable imaging and sensing with less noise than is classically possible. Additionally, entangled

Publications

Modular Autonomous Virtualization System for Two-Dimensional Semiconductor Quantum Dot Arrays

April 30, 2025

Author(s)

Anantha Rao, Donovan Buterakos, Barnaby van Straaten, Valentin John, Cécile Yu, Stefan Oosterhout, Lucas Stehouwer, Giordano Scappucci, Menno Veldhorst, Francesco Borsoi, Justyna Zwolak

Arrays of gate-defined semiconductor quantum dots are among the leading candidates for building scalable quantum processors. High-fidelity initialization

IMPPY3D: Image Processing in Python for 3D Image Stacks

April 2, 2025

Author(s)

Newell Moser, Alexander Landauer, Orion Kafka

Image Processing in Python for 3D image stacks, or IMPPY3D, is a free and open-source software (FOSS) repository that simplifies post-processing and 3D shape

X-ray computed tomography flaw phantom development: stepper photolithography and deep reactive ion etching: Fabrication and reference measurements

February 18, 2025

Author(s)

Felix Kim, Sarah Robinson, Nikolai Klimov, John Henry J. Scott

Stepper photolithography combined with deep reactive ion etching was used to generate controlled flaws to assess X-ray computed tomography (XCT) flaw

Autonomous bootstrapping of quantum dot devices

January 28, 2025

Author(s)

Anton Zubchenko, Danielle Middlebrooks, Torbjoern Rasmussen, Lara Lausen, Ferdinand Kuemmeth, Anasua Chatterjee, Justyna Zwolak

Semiconductor quantum dots (QDs) are a promising platform for multiple different qubit implementations, all of which are voltage controlled by programmable gate

Tools and Instruments

Large Aperture Scanner

The Large Aperture Scanner (LAS) scans a radar transceiver over a 5 meter by 20 meter aperture. Image reconstruction techniques enable a three-dimensional