Image & signal processing

News and Updates

New Device Design Brings Unparalleled Confidence to Cell Measurements

July 20, 2022

Measuring the numbers and properties of cells moving in a stream — a process called flow cytometry — is critically important to diagnostic medicine

Human figure stands facing large wooden board. Behind that is a row of tubes sticking up from a base.

NIST Method Uses Radio Signals to Image Hidden and Speeding Objects

June 25, 2021

Researchers at the National Institute of Standards and Technology (NIST) and Wavsens LLC have developed a method for using radio signals to create real-time

Escape From Flatland: Calibration Method Enables Microscopes to Make Accurate Measurements in All 3 Dimensions

June 24, 2021

Conventional microscopes provide essential information about samples in two dimensions — the plane of the microscope slide. But flat is not all that. In many

Projects and Programs

Quantitative, traceable determination of cell viability using absorbance microscopy

Ongoing

Most cell-based protocols require knowledge of the number of live and dead cell populations. The current methods, however, lack traceability, which is

Optical and Optoelectronic Materials Characterization

Ongoing

This project aims to develop rigorous measurements and methodology needed for determining optical and electrical properties of advanced materials that might be

Indoor Localization and Tracking

Ongoing

This web page is simply a pointer to another page that covers the extensive research program in indoor localization and tracking at NIST.

Sensing and Imaging of concealed objects

Ongoing

Emergency response, law enforcement and military personnel must face threats and dangerous situations as part of their jobs. These threats can vary from knives

Publications

High-speed, 3D volumetric displacement and strain mapping in soft materials using Light Field Microscopy

September 2, 2022

Author(s)

Selda Buyukozturk, Alexander Landauer, Jing Zhang, Luke Summey, Angel Chukwu, Christian Franck

Background: High strain-rate deformations of soft materials have several applications which presents an experimental need to measure at-rate 3D volumetric

Scalable additive construction of arrayed microstructures with encoded properties for bioimaging

August 25, 2022

Author(s)

Matthew DiSalvo, Belén Cortés Llanos, Cody LaBelle, David Murdoch, Nancy Allbritton

Microarrays are essential components of analytical instruments. The elements of microarrays may be imbued with additional functionalities and encodings using

Unmasking the Resolution–Throughput Tradespace of Focused-Ion-Beam Machining

August 21, 2022

Author(s)

Andrew Madison, John S. Villarrubia, Kuo-Tang Liao, Craig R. Copeland, Joshua Schumacher, Kerry Siebein, Robert Ilic, James Alexander Liddle, Samuel M. Stavis

Serial flow cytometry in an inertial focusing optofluidic microchip for direct assessment of measurement variations

July 20, 2022

Author(s)

Matthew DiSalvo, Paul Patrone, Anthony J. Kearsley, Gregory A. Cooksey

Flow cytometry is an invaluable technology in biomedical research, yet it has limited ability to separate inherent sample variability from measurement

Software

Custom Lifetime Imaging Platform (CLIP)

CLIP is an analysis program for fluorescence lifetime images. It provides the user with the ability to fit or calculate the phasor plots for lifetime decays

Tools and Instruments

Large Aperture Scanner

The Large Aperture Scanner (LAS) scans a radar transceiver over a 5 meter by 20 meter aperture. Image reconstruction techniques enable a three-dimensional