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Search Publications by: Matthew DiSalvo (Fed)

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Displaying 1 - 7 of 7

Advancing evanescent light scattering microscopy for single-particle characterization of gene delivery nanoparticles

March 4, 2026
Author(s)
Jagat Budhathoki, Gregory Cooksey, Matthew DiSalvo, Thomas Germer, Peter Bajcsy, Edward Kwee, Aaron Goldfain, Alexander Peterson
Precise and reproducible single-nanoparticle characterization is essential for advancing gene therapy, where viral vectors encapsulating therapeutic genes must be evaluated under formulation-relevant conditions. We present a label-free optical platform

Matching and comparing objects in a serial cytometer

October 4, 2020
Author(s)
Nikita Podobedov, Matthew DiSalvo, Jason A. Hsu, Paul Patrone, Gregory A. Cooksey
Flow cytometers are indispensable for clinical studies, yet are hindered by inherent uncertainties. We have developed an optofluidic device capable of multiple measurements along a microfluidic channel, whereby many of the uncertainty components can be

Serial microfluidic cytometry with inertial and hydrodynamic flow focusing

October 4, 2020
Author(s)
Matthew DiSalvo, Paul Patrone, Gregory A. Cooksey
Microfluidics are increasingly used to develop flow cytometers with novel functionalities. Although various approaches exist to control particle positioning within microfluidics, the magnitude and mechanisms of measurement uncertainties that arise from
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