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Search Publications by: Samuel M. Stavis (Fed)

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Displaying 51 - 60 of 60

Microfluidic Directed Self-Assembly of Liposome-Hydrogel Hybrid Nanoparticles

April 29, 2010
Author(s)
Jennifer S. Hong, Samuel M. Stavis, Silvia H. De Paoli Lacerda, Laurie E. Locascio, Srinivasa R. Raghavan, Michael Gaitan
We present a microfluidic method to direct the self-assembly of liposome-hydrogel hybrid nanoparticles. Our approach yields nanoparticle size distributions that are highly monodisperse and precisely controlled across a broad range relevant to the targeted

Microfluidic Mixing and the Formation of Nanoscale Lipid Vesicles

April 27, 2010
Author(s)
Andreas Jahn, Samuel M. Stavis, Jennifer S. Hong, Wyatt N. Vreeland, Don L. DeVoe, Michael Gaitan
We investigate the formation of unilamellar lipid vesicles (liposomes) with diameters of tens of nanometers by microfluidic hydrodynamic focusing (MHF). Our study includes liposome synthesis experiments and numerical modeling of our microfluidic

Accurate optical analysis of single molecule entrapment in nanoscale vesicles

January 1, 2010
Author(s)
Joseph E. Reiner, Andreas Jahn, Samuel M. Stavis, Michael J. Culbertson, Wyatt N. Vreeland, Daniel L. Burden, Jon C. Geist, Michael Gaitan
We present a non-destructive method to characterize low analyte concentrations in nanometer scale lipid vesicle formulations. Our method is based on the application of fluorescence fluctuation analysis (FFA) and multi-angle laser light scattering (MALLS)

Nanofluidic Structures with Complex Three Dimensional Surfaces

March 31, 2009
Author(s)
Samuel M. Stavis, Elizabeth Strychalski, Michael Gaitan
A fabrication process was developed to construct nanofluidic devices with complex three dimensional (3D) topographies. A single layer of grayscale photolithography enabled arbitrary and simultaneous control of numerous nanoscale etch depths in a fused

Single Molecule Analysis of Electrodynamically Stretched DNA in Nanochannels

October 13, 2008
Author(s)
Samuel M. Stavis, Christian H. Reccius, John T. Mannion, Larry P. Walker, Harold G. Craighead
A rapid (~20 ms) and precise (~110 nm) analytical method is presented for stretching and interrogating single DNA molecules. Conformation, length, speed and fluorescence intensity measurements are obtained simultaneously. This confluence is a step forward