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Search Publications by: Young Jong Lee (Fed)

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Displaying 26 - 43 of 43

Quantitative, label-free characterization of stem cell differentiation at the single-cell level by broadband coherent anti-Stokes Raman scattering microscopy

December 31, 2014
Author(s)
Marcus T. Cicerone, Young J. Lee, Khaled A. Aamer, Prabhas V. Moghe, Sebastian L. Vega, Parth J. Patel
We use broadband coherent anti-Stokes Raman scattering (BCARS) microscopy to characterize lineage commitment of individual human mesenchymal stem cells (hMSCs) cultured in adipogenic, osteogenic, and basal culture media. We treat hyperspectral images

High-Speed Coherent Raman Fingerprint Imaging of Biological Tissues

July 20, 2014
Author(s)
Charles H. Camp, Young J. Lee, John M. Heddleston, Christopher M. Hartshorn, Angela R. Hight Walker, Jeremy N. Rich, Justin D. Lathia, Marcus T. Cicerone
We have developed a coherent Raman imaging platform using broadband coherent anti-Stokes Raman scattering (BCARS) that provides an unprecedented combination of speed, sensitivity, and spectral breadth. The system utilizes a unique configuration of laser

Multicomponent Chemical Imaging of Pharmaceutical Solid Dosage Forms with Broadband CARS Microscopy

July 15, 2013
Author(s)
Christopher M. Hartshorn, Marcus T. Cicerone, Young J. Lee, Charles H. Camp, John M. Heddleston, Patrick Marsac, Tim Rhodes, Zhen Liu, Nicole Canfield
We compare broadband coherent anti-Stokes Raman scattering (BCARS) microscopy with spontaneous Raman microscopy for quantitative and qualitative assessment of multicomponent pharmaceuticals. Indomethacin was used as a model active pharmaceutical ingredient

LTB4 IS A SIGNAL RELAY MOLECULE DURING NEUTROPHIL CHEMOTAXIS

May 15, 2012
Author(s)
Philippe V. Afonso, Mirkka Janka-Junttila, Young Jong Lee, Colin P. McCann, Charlotte M. Oliver, Khaled A. Aamer, Wolfgang Losert, Marcus T. Cicerone, Carol A. Parent
Neutrophil recruitment to inflammation sites purportedly depends on sequential waves of chemoattractants. Current models propose that LTB4, a secondary chemoattractant secreted by neutrophils in response to primary chemoattractants such as formyl-peptides

Pulse shaping for background free broadband CARS

March 16, 2009
Author(s)
Young Jong Lee, Marcus T. Cicerone
We demonstrate that pulse shaping of a probe pulse can suppress the nonresonant background (NRB) contribution and retrieve resonant Raman signal efficiently in broadband coherent anti-Stokes Raman scattering (CARS) spectrum. A pulse shaper prepares a probe

Measuring the Modulus of Hydrated Contact Lenses via Surface Wrinkling

April 6, 2008
Author(s)
Jun Y. Chung, Young Jong Lee, Peyton Hopson, Michael J. Fasolka, Christopher Stafford
One of the most important considerations in the evaluation of hydrogels for biomedical and contact lens applications is the elastic modulus. The elastic modulus relates to several important factors including flexibility, comfort, adhesion, swelling

Characterization of 3-Color CARS in a 2-Pulse Broadband CARS Spectrum

November 15, 2007
Author(s)
Young Jong Lee, Marcus T. Cicerone, Yuexin Liu
We present a new and simple approach to broadband coherent anti-Stokes Raman scattering (CARS) microscopy that yields background-free vibrational spectra. We present evidence for a mechanism where two different frequency components in a continuum pulse

Real-Time Monitoring of Polymer Nanocomposites Composition during Extrusion Compounding

September 1, 2004
Author(s)
Rick D. Davis, Jeffrey W. Gilman, Anthony J. Bur, M M. McBrearty, P R. Start, Young J. Lee
Dielectirc spectroscopy was conducted during extrusion processing of polyamide-6 (PA6) and layered silicate/polyamide-6 manocomposites. Dielectric dispersion parameteers were identified that appear sensitive to layered silicate concentration and degree of
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