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Search Publications by: Joseph Robertson (Fed)

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Displaying 26 - 50 of 50

PEG-Labeled Nucleotides and Nanopore Detection for Single Molecule DNA Sequencing by Synthesis

September 21, 2012
Author(s)
Shiv Kumar, Tao Chuanjuan, Chien Minchen, Hellner Brittney, Joseph W. Robertson, Arvind Balijepalli, Li Zengmin, James J. Russo, Joseph E. Reiner, John J. Kasianowicz, Jingyue Ju
There is a significant need to accurately sequence single DNA and RNA molecules for personalized medicine. We describe a novel nanopore-based sequencing by synthesis (SBS) strategy that will accurately differentiate at single molecule level four different

SEM Induced Shrinking of Solid State Nanopores for Single Molecule Detection

September 22, 2011
Author(s)
Anmiv Prahbu, Kevin J. Freedman, Joseph W. Robertson, Zhorro Nikolov, John J. Kasianowicz, MinJun Kim
We have investigated the shrinkage of solid state nanopores by a scanning electron microscope and find the process to be reproducible and dependant beam parameters such as the accelerating voltage and electron flux. The shrinking phenomenon does not

Electron-exchange assisted photon energy up-conversion in thin films of ?-conjugated polymeric composites

August 4, 2011
Author(s)
Panagiotis Keivanidis, Frederic Laquai, Joseph W. Robertson, Baluschev Stanislav, Josemon Jacob, Klaus Mullen, Gerhard Wegner
The mechanism of triplet-triplet annihilation (TTA) induced up-converted delayed luminescence is studied in two different binary organic systems consisting of platinum(II) octaethyl porphyrin mixed with either poly(fluorene) (PF26) or ladder-type

Theory for Polymer Analysis Using Nanopore-based Single-molecule Mass Spectrometry

June 1, 2010
Author(s)
Joseph E. Reiner, John J. Kasianowicz, Brian J. Nablo, Joseph W. Robertson
Nanometer-scale pores have demonstrated potential as a tool for the electrical detection and characterization of molecules. To provide a physical basis for nanopore-based analytical metrology, we show that a simple model quantitatively describes how one

Sizing the Bacillus anthracis PA63 Channel with Nonelectrolyte Poly(ethylene glycols)

August 1, 2008
Author(s)
Brian J. Nablo, Kelly Halverson, Joseph W. Robertson, Tam Nguyen, Rekha Panchal, Rick Gussio, Sina Bavari, Oleg V. Krasilnikov, John J. Kasianowicz
Non-electrolyte polymers of poly(ethylene glycol), PEG, were used to estimate the diameter of the ion channel formed by Bacillus anthracis protective antigen 63, PA63. Based on the ability of different molecular weight PEGs to partition into the pore and

Nanoscopic Porous Sensors

July 1, 2008
Author(s)
John J. Kasianowicz, Joseph W. Robertson, Elaine Chan, Joseph E. Reiner, Vincent M. Stanford
There are thousands of different nanometer-scale pores in biology,many of which act as sensors for specific chemical agents. Recent work suggests that protein and solid-state nanopores have many potential uses in a wide variety of analytical applications

Stable Insulating Tethered Bilayer Lipid Membranes

June 2, 2008
Author(s)
Inga K. Vockenroth, Christian Ohm, Joseph W. Robertson, Duncan J. McGillivray, Mahias Losche, Ingo Koper
Tethered bilayer lipid membranes have been shown to be an excellent model system for biological membranes. Coupling of a membrane to a solid supports creates a stable system that is accessible for various surface analytical tools. Good electrical sealing

Single Molecule Mass Spectrometry in Solution Using a Solitary Nanopore

May 15, 2007
Author(s)
Joseph W. Robertson, Claudio G. Rodrigues, Oleg V. Krasilnikov, Vincent M. Stanford, Kenneth A. Rubinson, John J. Kasianowicz
A solitary protein nanometer-scale pore provides the basis for single molecule mass spectrometry in solution. Individual poly(ethylene glycol) molecules of different mass that enter a nanopore cause distinct and statistically resolved conductance states