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Publications

Search Publications by

William A MacCrehan (Assoc)

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Displaying 1 - 25 of 36

A Comparison of Measurement Methods for Alcohol-Based Hand Sanitizers

February 26, 2021
Author(s)
Mary Bedner, Jacolin Murray, Aaron A. Urbas, William A. MacCrehan, Walter Brent Wilson
The production and demand for hand sanitizers have increased dramatically during the coronavirus disease 2019 (COVID-19) health emergency. To be deemed effective and safe, hand sanitizers should contain at least 60 % alcohol (typically ethanol) as well as

Two-temperature preparation method for PDMS-based canine training aids for explosives

October 8, 2020
Author(s)
William A. MacCrehan, Mimy Young, Michele M. Schantz, T C. Angle, Paul Waggoner, Terrance Fisher
Training aids based on vapor capture-and-release into a flexible polymer, polydimethylsiloxane (PDMS), have proven successful in canine detection of explosives that have volatile or semi- volatile odorants. To enhance the rate of odor capture for less

NIST Micronutrients Measurement Quality Assurance Program: 1984-1985 Comparability Studies Results for Round Robins I, II, III and V Fat Soluble Vitamins and Carotenoids in Human Serum

February 8, 2019
Author(s)
Jeanice M. Brown Thomas, David L. Duewer, Margaret C. Kline, William A. MacCrehan, Robert Paule, Reenie Parris, Willie May, Robert Schaffer
From 1984 to 2017, the National Institute of Standards and Technology (NIST) and its precursor the National Burearu of Standards (NBS) coordinated what became the Micronutrients Measurement Quality Assurance Program (MMQAP) for laboratories that measure

PEGylation of zinc nanoparticles amplifies their ability to enhance olfactory responses to odorant

December 20, 2017
Author(s)
Melissa Singletary, Samantha Hagerty, Shinichiro Muramoto, Yasmine Daniels, William A. MacCrehan, Gheorghe Stan, June W. Lau, Oleg Pustovyy, Ludmila Globa, Edward E. Morrison, Iryna Sorokulova, Vitaly Vodyanoy
Responses of olfactory sensory neurons to odorants are intensely enhanced with the addition of small endogenous and engineered zinc nanoparticles, as shown by physiological experiments. The highest enhancement was recorded with 1.2 nm non-oxidized zinc

Biomimetic Sniffing with an Artificial Dog’s Nose Leads to Improvements in Vapor Sampling and Detection

December 1, 2016
Author(s)
Matthew E. Staymates, William A. MacCrehan, Jessica L. Staymates, John G. Gillen, Brent Craven, Rod Kunz, Ted Mendum, Ta-Hsuan Ong
This work presents fluid flow visualization studies and chemical detection experiments using an 3D printed anatomically-correct biomimetic canine nose from a female Labrador retriever. Schlieren imaging, high-speed videography, along with flow

After oxidation, zinc nanoparticles lose their ability to enhance responses to odorants

September 20, 2016
Author(s)
Samantha Hagerty, Yasmine C. Daniels, Melissa Singletary, Oleg Pustovyy, Ludmila Globa, William A. MacCrehan, Shinichiro Muramoto, June W. Lau, Edward Morrison, Iryna Sorokulova, Vitaly Vodyanoy, Gheorghe Stan
Electrical responses of olfactory sensory neurons to odorants were examined in the presence of zinc nanoparticles of various sizes and degrees of oxidation. The zinc nanoparticles were prepared by the underwater electrical discharge method and analyzed by

Engineered metal nanoparticles in the sub-nanomolar levels kill cancer cells

April 18, 2016
Author(s)
Yasmine C. Daniels, William A. MacCrehan, Shinichiro Muramoto, Gheorghe NMN Stan, Vitaly Vodyanoy, Oleg Pustovyy
Zinc and copper metal nanoparticles were produced from bulk metal rods by an underwater high-voltage discharge method. The metal nanoparticles, with estimated diameters of 1 nm to 2 nm, were determined to be more than 85 % non-oxidized. Exposure of rat RG2

Ag/AgCl Microelectrodes with Improved Stability for Microfluidics

March 30, 2006
Author(s)
Brian J. Polk, Anna Stelzenmuller, Geraldine I. Mijares, William A. MacCrehan, Michael Gaitan
A method for fabricating Ag/AgCl planar microelectrodes for microfluidic applications is presented. Microreference electrodes enable accurate measurements with miniaturized chemical sensors but such electrodes often exhibit very limited useable lifetimes

Derivatization of Plastic Microfluidic Devices With Polyelectrolyte Multilayers

May 1, 2000
Author(s)
S L. Barker, Michael J. Tarlov, M L. Branham, J Xu, William A. MacCrehan, Michael Gaitan, Laurie E. Locascio
Microchannels fabricated in plastic materials by room temperature imprinting demonstrate large variability in surface charge as a result of the fabrication procedure. Surface charged groups are primarily localized on the channel walls and not on the