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Displaying 401 - 425 of 1412

A Novel Mechanism for Regulating the Activity of Proliferating Cell Nuclear Antigen by a Small Protein

March 10, 2014
Author(s)
Zvi Kelman, Richard Y. Huang, Zhuo Li, Jerard Hurwitz, Santangelo J. Thomas, Travis H. Hileman, Yopp C. Daniel, Jeffrey W. Hudgens
Chromosomal DNA replication requires the regulated activity of large number of proteins and complexes. Proliferating cell nuclear antigen (PCNA) protein forms a homotrimeric ring that associates with, and regulates the activity of, many proteins

Inhibition of DNA glycosylases via small molecule purine analogs

December 9, 2013
Author(s)
M Miral Dizdar, Aaron C. Jacobs, Ajit Jadhav, Dorjbal Dorjsuren, David Maloney, Anton Simeonov, Pawel Jaruga, Amanda K. McCullough, R. S. Lloyd
Following the formation of oxidatively-induced DNA damage, several DNA glycosylases are required to initiate repair of the base lesions that are formed. Recently, NEIL1 and other DNA glycosylases, including OGG1 and NTH1 were identified as potential

Active Transcriptomic and Proteomic Reprogramming in the C. elegans Nucleotide Excision Repair Mutant xpa-1

April 9, 2013
Author(s)
Katarzyna Arczewska, Gisele Tomazella, Jessica Lindvall, Henok Kassahun, Silvia Maglioni, Alessandro Torgovnick, Johan Henriksson, Olli Matilainen, Bryce J. Marquis, Bryant Nelson, Eshrat Babaie, Carina Holmberg, Thomas Burglin, Natascia Ventura, Bernd Thiede, Hilde Nilsen
Transcription-blocking oxidative DNA damage is believed to contribute to aging and to underlie activation of oxidative stress-responses and down-regulation of insulin-like signaling (ILS) in Nucleotide Excision Repair (NER) deficient mice. Here, we present

Semiconductor Nanocrystal Probes for Human Metaphase Chromosomes

February 1, 2004
Author(s)
Yan Xiao, Peter E. Barker
Novel inorganic fluorophores called semiconductor nanocrystals have recently been incorporated into protein, antibody and microbead oligonucleotide detection methods where previously, organic dyes were universally employed. To improve quantitation of

Genomic DNA of Nostoc Commune (Cyanobacteria) Becomes Covalently Modified During Long-Term (Decades) Desiccation But Is Protected From Oxidative Damage and Degradation

June 15, 2003
Author(s)
B Shirkey, N J. McMaster, Sue C. Smith, D J. Wright, H Rodriguez, Pawel Jaruga, M Birincioglu, R F. Helm, M Potts
Genomic DNA of Nostoc commume (Cyanobacteria) became covalently modified during decades of desiccation. Amplification of gene loci from desiccated cells required pretreatment of DNA with N-phenacylthiazolium bromide; a reagent that cleaves DNA- and protein

The Protein Data Bank: Unifying the Archive

January 1, 2002
Author(s)
J Westbrook, Z. Feng, Sanjay Jain, Talapady N. Bhat, N Thanki, Veerasamy Ravichandran, G L. Gilliland, W Bluhm, H Weissig, D S. Greer, P E. Bourne, H M. Berman
The Protein Data Bank (PDB; http://www.pdb.org/) is the single worldwide archive of structural data of biological macromolecules. This paper describes the progress that has been made in validating all data in the PDB archive and in releasing a uniform

The PDB Data Uniformity Project

January 1, 2001
Author(s)
Talapady N. Bhat, P E. Bourne, Z. Feng, G L. Gilliland, Sanjay Jain, Veerasamy Ravichandran, B. Schneider, K. Schneider, N Thanki, H Weissig, J Westbrook, H M. Berman
The Protein Data Bank (PDB; http://www.rcsb.org/pdb/) is the single worldwide archive of structural data of biological macromolecules. This paper describes the data uniformity project that is underway to address the inconsistency in PDB data.

The Protein Data Bank

January 1, 2000
Author(s)
H M. Berman, J Westbrook, Z. Feng, G L. Gilliland, Talapady N. Bhat, H Weissig, N Shindyalov, P E. Bourne
The Protein Data Bank (PDB) is the single worldwide repository of structural data of biological macromolecules. This paper describes the goals of the PDB, the systems in place for data deposition and access, how to obtain further information, and near-term

Towards fast screening of organic solar cell blends

August 5, 2020
Author(s)
Lee Richter, Artem Levistsky, Giovanni M. Matrone, Aditi Khirbat, Ilaria Bargigia, Xiaolei Chu, Oded Nahor, Tamar Segal-Perez, Adam Moule, Carlos Silva, Natalie Stingelin, Gitti L. Frey
… (PCE11) : phenyl-C61-butyric acid-methyl-ester acceptor (PCBM) blend systems, we demonstrate that by …

Molecular Order in High-Efficiency Polymer/Fullerene Bulk Heterojunction Solar Cells

September 22, 2011
Author(s)
Matthew R. Hammond, Regis J. Kline, Andrew A. Herzing, Lee J. Richter, David Germack, Hyun W. Ro, Christopher L. Soles, Daniel A. Fischer, Tao Xu, Luping Yu, Michael F. Toney, Dean M. DeLongchamp
… efficiency when blended with [6,6]-phenyl-C71-butyric acid methyl ester (PC71BM). A surprisingly low degree of order was found …

CCQMK62: Nutrients in Infant/Adult Formula Vitamins: Final Report

April 24, 2010
Author(s)
Katherine E. Sharpless, Catherine A. Rimmer, Karen W. Phinney, Bryant C. Nelson, David L. Duewer, Stephen A. Wise
… and the range of their chemical properties: folic acid (vitamin B9) is a single water-soluble molecular entity … ccqm, key comparison, k62, vitamin, infant, formula, folic acid, niacin, retinol, retinyl …
Displaying 401 - 425 of 1412
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