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Marija Dubackic, Yun Liu, Elizabeth Kelley, Crispin Hetherington, Michael Haertlein, Juliette Devos, Sara Linse, Emma Sparr, Ulf Olsson
α-Synuclein (aSyn) is a 140 residue long protein that is present in presynaptic termini of nerve cells. The protein is also pathologically associated with Parkinson's disease, where it has been found to self-assemble into long amyloid fibrils forming
Christopher Soles, Amanda L. Forster, Katherine Evans, Madhusudan (Madhu) Tyagi, Robert M. Elder, Timothy Sirk, Joseph Dennis, Kanae Ito, Osama Yamamuro, Hiroshi Akiba
Modern design of common adhesives, composites and polymeric parts makes use of polymer glasses that are stiff enough to maintain their shape under a high stress while still maintaining a ductile behavior after the yield point. Typically, material
Van Ngo, Maria Queralt-Martin, Farha Khan, Lucie Bergdoll, Jeff Abramson, Sergey M. Bezrukov, Tatiana Rostovtseva, David Hoogerheide, Sergei Noskov
The voltage-dependent anion channel (VDAC) is a β-barrel channel of the mitochondrial outer membrane (MOM) that passively transports ions, metabolites, polypeptides, and single-stranded DNA. VDAC responds to a transmembrane potential by transitioning to a
Charles Majkrzak, Norman F. Berk, Brian B. Maranville, Joseph Dura, Terrence J. Jach
In the analysis of neutron scattering measurements of condensed matter structure, it normally suffices to treat the incident and scattered neutron beams as if composed of incoherent distributions of plane waves with wavevectors of different magnitudes and
Laura E. Dalton, Jacob LaManna, Scott Jones, Mohammad Pour-Ghaz
The contributions of the interfacial transition zone (ITZ) to mass transport in cement-based materials remain ambiguous and disputed. In this study, the neutron and X-ray tomography (NeXT) system is used to capture unsaturated moisture flow in a concrete
Ali Slim, Winnie Shi, Farshad S. Samghabadi, Antonio Faraone, Amanda Marciel, Ryan Poling-Skutvik, Jacinta Conrad
We investigate the structure and dynamics of unentangled semidilute solutions of sodium polystyrene sulfonate (NaPSS) using small-angle neutron scattering (SANS) and neutron spin-echo (NSE) spectroscopy. The effects of electrostatic interactions and chain
Jamie Weaver, Fabian Linsenmann, Philip Rapp, Markus Trunk, Roman Gernh?user, Bastian M?rkisch, Hubert Gasteiger
Spinel-type LiNi0.5Mn1.5O4 (LNMO) is one of the most promising 5 V-class cathode materials for Li-ion batteries that can achieve high energy density and low production costs. However, in liquid electrolyte cells, the high voltage causes continuous cell
Spinel-type LiNi0.5Mn1.5O4 (LNMO) is one of the most promising 5 V-class cathode materials for Li-ion batteries that can achieve high energy density and low production costs. However, in liquid electrolyte cells, the high voltage causes continuous cell
Kishan Bellur, Ezequiel Medici, Daniel Hussey, David Jacobson, Jacob LaManna, Juscelino Leao, Julia Scherschligt, James Hermanson, Chang Kyoung Choi, Jeffrey Allen
Predicting evaporation and cryo-storage behavior of liquid hydrogen poses a challenge for both terrestrial energy infrastructure and long term space missions. The current understanding of cryogenic phase change and subsequent boil-off is limited, in part
Changwoo Do, Rana Ashkar, Cristina Boone, Wei-Ren Chen, Georg Ehlers, Peter Falus, Antonio Faraone, Jason Gardner, Van Graves, Thomas Huegle, Reika Katsumata, Darian Kent, Jiao Lin, Bill Mchargue, Bradley D. Olsen, Yangyang Wang, Danielle Wilson, Y. Z.
EXPANSE, an EXPanded Angle Neutron Spin Echo instrument, has been proposed and selected as one of the first suite of instruments to be built at the Second Target Station of the Spallation Neutron Source at the Oak Ridge National Laboratory. This instrument
The success and continued expansion of research in polyoxometalates (POMs) owe largely to their structural richness and wide range of functions. However, while most POM clusters known to date are negatively charged, there is only a handful of cationic POMs
Alexander Romanyukha, Jacob LaManna, Alan Keith Thompson, Keith Consani, Jessica Mintz
To accurately determine dose, albedo TLD dosimeters require application of a neutron energy correction factor (NECF). In this paper, the results from three different methods were used to determine NECFs. In the first method, NECF values were calculated as
Martin Wissink, Kirk Goldenberger, Luke Ferguson, Yuxuan Zhang, Hassina Bilheux, Jacob LaManna, David Jacobson, Michael Kass, Charles Finney, Jonathan Willocks
Neutron imaging offers deep penetration through many high-Z materials while also having high sensitivity to certain low-Z isotopes such as 1H, 6Li, and 10B. This unique combination of properties has made neutron imaging an attractive tool for a wide range
Stuart R. Castillo, Brett W. Rickeard, Mitchell DiPasquale, Michael H. Nguyen, Aislyn Lewis-Laurent, Milka Doktorova, Batuhan Kav, Markus S. Miettinen, Michihiro Nagao, Elizabeth Kelley, Drew Marquardt
Pancratistatin (PST) is a natural antiviral alkaloid that has demonstrated specificity towards cancerous cells and explicitly targets the mitochondria. PST initiates apoptosis while leaving healthy, noncancerous cells unscathed. However, the manner by
Small-angle neutron scattering (SANS) has been a beneficial tool for studying the structure of biological macromolecules in solution for several decades. Continued improvements in sample preparation techniques, including deuterium labeling, neutron
Lipid bilayers are a key component of cell membranes and play a crucial role for life and in bio-nanotechnology. As a result, controlling their physicochemical properties holds the promise of effective therapeutic strategies. Ionic liquids (ILs) – a vast
Ohsung Oh, Youngju Kim, Daeseung Kim, Daniel Hussey, Seung Wook Lee
Grating interferometry is a promising technique to obtain differential phase contrast images with illumination source of low intrinsic transverse coherence. However, retrieving the phase contrast image from the differential phase contrast image is
D. Sweeney, Susan T. Krueger, Kakali Sen, John Hackett
Nanolipoprotein particles known as nanodiscs (NDs) have emerged as versatile and powerful tools for the stabilization of mem-brane proteins permitting a plethora of structural and biophysical studies. Part of their allure is their flexibility to
Peng Luo, Yanqin Zhai, Peter Falus, Victoria Garcia Sakai, Monika Hartl, Maiko Kofu, Kenji Nakajima, Antonio Faraone, Y. Z
Employing high-intensity wide-angle neutron spin-echo spectroscopy, we measured the coherent intermediate scattering function of the prototypical ionic glass former Ca 0.4K 0.6(NO 3) 1.4 in the equilibrium and supercooled liquid state from 383 to 519 K
Erkan Senses, Christopher Kitchens, Antonio Faraone
The addition of nanoparticles to a polymer matrix can in certain cases induce a reduction in viscosity, with respect to the pure matrix, in the resulting composites. This counterintuitive phenomenon cannot be explained using the most common rheological
Amy Y. Xu, Nicholas J. Clark, Joseph Pollastrini, Maribel Espinoza, Hyo-Jin Kim, Sekhar Kanapuram, Bruce Kerwin, Michael J. Treuheit, Susan T. Krueger, Arnold McAuley, Joseph E. Curtis
Igor K. Mkam Tsengam, Marzhana Omarova, Elizabeth Kelley, Alon V. McCormick, Geoffrey D. Bothun, Srinivasa R. Raghavan, Vijay T. John
The phospholipid lecithin (L) and the nonionic surfactant Tween 80 (T) are used together in various contexts, including in drug delivery and oil spill remediation. There is hence a need to elucidate the nanostructures in L/T mixtures, which is the focus of